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Mangalore, India

Selva Murugan A.,Tirunelveli Medical College | Manivasagam,Government O E Multi Specialty Hospital And Medical College
Journal of South India Medicolegal Association | Year: 2015

Accidental causes contribute a major share in causing sudden death of toddler age group. Among these, choking by foreign bodies is quite common. Choking by definition, to reduce the lumen of a tube, finds its importance in mechanical asphyxia and fire arms in relation to Forensic field. This is a case report of one such death, possible scenic reconstruction and medico legal issues out of that death. © 2015 South India Medico-Legal Association. All rights reserved.

Balasubramanian R.,National University of Singapore | Nainar P.,Tirunelveli Medical College | Rajasekar A.,National University of Singapore
Aerobiologia | Year: 2012

Limited data are currently available on the concentrations of airborne bacteria, fungi, and endotoxins in indoor environments. The levels of aerial bacteria and fungi were measured at several microenvironments within a well-ventilated residential apartment in Singapore including the living room, kitchen, bedroom, toilet, and at a workplace environment by sampling indoor air onto culture medium plates using the 6-stage Andersen sampler. Total microbial counts were determined by collecting the air samples in water with the Andersen sampler, staining the resultant extracts with a fluorescent dye, acridine orange, and counting the microbes using a fluorescent microscope. The levels of airborne endotoxins were also determined by sampling the airborne microorganisms onto 0.4 μm polycarbonate membrane filter using the MiniVol sampler at 5 l/min for 20 h with a PM2.5 cut-off device. The aerial bacterial and fungal concentrations were found to be in the ranges of 117-2,873 CFU/m 3 and 160-1,897 CFU/m3, respectively. The total microbial levels ranged from 49,000 to 218,000 microbes/m3. The predominant fungi occurring in the apartment were Aspergillus and Penicillium while the predominant bacterial strains appeared to be Staphylococcus and Micrococcus. The average indoor endotoxin level was detectable in the range of 6-39 EU/m 3. The amount of ventilation and the types of human activities carried out in the indoor environment appeared to be important factors affecting the level of these airborne biological contaminants. © 2011 Springer Science+Business Media B.V.

Raju S.,Krishna Hospitals | Kalyanaraman S.,Tirunelveli Medical College | Swaminathan K.,Tirunelveli Medical College | Nisha A.,Krishna Hospitals | Praisid S.,Krishna Hospitals
Indian Journal of Pediatrics | Year: 2014

Hemophagocytic lymphohistiocytosis (HLH) is a life threatening florid activation of macrophages of the lymphoreticular system. It is reported to be associated with dengue in children in India and carries a high mortality. Patients present with high fever, worsening blood cell counts, splenomegaly, abnormal liver enzymes with features of liver failure, coagulopathy and neurological complications. The diagnosis is according to “Diagnostic Guidelines for HLH 2004”, based on a triad of clinical, blood parameters and bone marrow cytology. In the present study, data of 212 children admitted with dengue were analyzed. Of 212 children, 31 children were classified as suspect HLH and advised bone marrow evaluation; of whom 23 children had marrow evidence of HLH. Worsening of blood cell counts were recorded in all children with a mean platelet count of 58,303.03 cells/cumm, low hematocrit in 95.65 %, low mean hemoglobin level of 8.37 g/dL, high erythrocyte sedimentation rate (ESR) and prolonged pro-thrombin time/international normalization ratio (PT/INR). Serum triglycerides, ferritin and transaminases were high. Of the 23 children, 19 patients received intravenous immunoglobulin (IVIG) and all of these children recovered. Dengue with multi-organ dysfunction is commonly concurrent to HLH in the marrow and hence, an early diagnosis based on clinical, laboratory and bone marrow evaluation is significant. A bone marrow evaluation confirms the diagnosis of HLH. © 2014, Dr. K C Chaudhuri Foundation.

Sucilathangam G.,Tirunelveli Medical College | Palaniappan N.,Tirunelveli Medical College | Sreekumar C.,Tamil Nadu Veterinary and Animal Sciences University | Anna T.,Tamil Nadu Veterinary and Animal Sciences University
Indian Journal of Medical Microbiology | Year: 2010

Purpose: The purpose of the study was to determine the prevalence of Toxoplasma antibodies in selected immunocompetent and immunodeficient patients in and around Tirunelveli District of Tamil Nadu. Materials and Methods: This study was carried out from May 2006 to October 2007 in 175 immunodeficient and 175 immunocompetent patients. Serum samples were subjected into in-house IgG assay using indirect fluorescent antibody test (IFAT). Results: Out of 350 patients tested by IgG IFAT, 41 (11.71%) had antibodies for Toxoplasma gondii with a mean IFA titre of 43.42 ± 58.7 and the titre ranging from 1 : 16 to 1 : 256. Among the immunocompetent and immunodeficient groups, 19 patients (10.86%) and 22 patients (12.57%), respectively, had antibodies to T. gondii. Various risk factors associated within the study group was analysed and results were interpreted. Conclusions: The study has highlighted an overall seroprevalence of 11.71% with 12.57% in immunocompromised and 10.86% in immunocompetent patients respectively in a southern district, Tamil Nadu, which underlines the importance of screening of this parasite especially in the immunocompromised patients.

Joel J.M.,Tirunelveli Medical College | Jeyasingh S.D.,Tirunelveli Medical College | Kalyanaraman S.,Tirunelveli Medical College
Journal of Clinical and Diagnostic Research | Year: 2016

Biliary cystadenoma is a rare cystic neoplasms of liver that usually occurs in middle-aged women characterized by multiloculated cysts with internal septae and mural nodules. Unilocular biliary cystadenomas are rare and are difficult to differentiate from other cysts by radiology. Biliary cystadenomas are slow growing benign lesions that are easily resectable with a reported recurrence rate of 90% when the resection is incomplete. We present a case of 65-year-old male with unilocular biliary cystadenoma with mesenchymal stroma who presented with abdominal pain and distension. Laparotomy followed by cystectomy was done and postoperative period was uneventful with no abnormal biochemical, heamatological or imaging findings. Preoperative radio-imaging techniques may not always be helpful in arriving at a specific diagnosis in such cases. Hence thorough sampling and a careful histopathological examination is considered gold standard for specific diagnosis. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved.

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