Tianjin Tasly Pharmaceutical Co.

Tianjin, China

Tianjin Tasly Pharmaceutical Co.

Tianjin, China

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XIONG C.,Hubei University of Chinese Medicine | XIONG C.,Chinese Institute of Materia Medica | HU Z.-G.,Hubei University of Chinese Medicine | HU Z.-G.,Chinese Institute of Materia Medica | And 12 more authors.
Chinese Journal of Natural Medicines | Year: 2016

Hyoscyami Semen, the mature dried seed of Hyoscyamus niger L., has long been used as a traditional Chinese medicine to treat human diseases. Hyoscyami Semen is found in local markets in China. In markets, sellers and buyers commonly inadvertently mix the seeds of H. niger with the seeds of related species such as Hygrophila salicifolia (Vahl) Nees, Astragalus complanatus R. Br., Cuscuta australis R. Br., Cuscuta chinensis Lam., and Impatiens balsamina L. because of their similar morphologies or similar names. Thus, developing a reliable method for discriminating H. niger seeds from its adulterants is necessary to reduce confusion and ensure the safe use of Hyoscyami Semen. The present study was designed to evaluate the efficiency of high-resolution melting analysis combined with DNA barcoding (Bar-HRM) with internal transcribed spacer 2 to discriminate H. niger. Our results show that Bar-HRM successfully identified the adulterants and detected the proportion of H. niger DNA extract within an admixture. In particular, HRM detected H. niger DNA extract in A. complanatus DNA extract at concentrations as low as 1%. In conclusion, the Bar-HRM method developed in the present study for authenticating H. niger is rapid and cost-effective. It can be used in the future to guarantee the purity of Hyoscyami Semen for the clinical use. © 2016 China Pharmaceutical University


Na P.,Tianjin University | Jia X.,Tianjin University | Yuan B.,Tianjin University | Li Y.,Tianjin University | And 3 more authors.
Journal of Chemical Technology and Biotechnology | Year: 2010

BACKGROUND: Arsenic pollution in drinking water has been found in most countries. Arsenate (As(V)) and arsenite (As(III)) are two major forms of inorganic arsenic species, and the latter is the more toxic. The removal of arsenic ions from water has attracted increased attention, and therefore further understanding and development of techniques for removal of arsenic ions are required. RESULTS: Adsorption of arsenate and arsenite from aqueous solutions using Ti-pillared montmorillonite (Ti-MMT) was investigated as a function of contact time, pH, temperature, coexisting ions, and ionic strength. The adsorption of both arsenate and arsenitewere temperature and pH dependent, indicating different adsorption mechanisms. The effect of coexisting ions on the adsorptionwas also studied and, amongthe ions investigated, only phosphate had a noticeable influence on the adsorption of arsenate, while the effect of other ions was negligible. A pseudo-second-order chemical reaction model was obtained for both arsenate and arsenite; adsorption isotherms of arsenate and arsenite fitted the Langmuir and Freundlich isothermmodels well. X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) were used to study the nature of surface elements before and after adsorption. CONCLUSIONS: This work demonstrates that Ti-pillaredmontmorillonite is an efficient material for the removal of arsenate and arsenite from aqueous solutions. Experimentalparameters such as contact time, solution pH, temperature, initial concentration, coexisting ions, and ionic strength have been optimized. © 2010 Society of Chemical Industry.


Wang W.,Tianjin University of Traditional Chinese Medicine | Ye Z.,Tianjin Tasly Pharmaceutical Company Ltd | Song L.,Tianjin Tasly Pharmaceutical Company Ltd | Shen W.,Nanjing Agricultural University | And 3 more authors.
Zhongguo Zhongyao Zazhi | Year: 2010

Objective: To study the chromatographic fingerprint of the fruits of Schisandra chinensis, and identify the peaks. Method: Analysis was performed at 30°C on a Waters Symmetry C 18 column (4.6 mm x 250 mm, 5 μm), eluted with acetonitrile-water gradient elution. The flow-rate was 1.0 mL·min -1, and detection wavelength was 2i8 nm. The peaks in the chromatogram were identified by LC-MS. Result: The fingerprint of the fruits of S. chinensis was established, and fifteen peaks of lignans were identified. Conclusion: The method was easy, reliable and could be used as a powerful tool for the further quality control of S. chinensis.


Liu J.-L.,Northwest University, China | Qi Z.-H.,Tianjin Tasly Pharmaceutical Co. | Huang X.,Northwest University, China | Liu F.-H.,Tianjin Tasly Pharmaceutical Co. | And 2 more authors.
Chinese Journal of Applied Ecology | Year: 2014

A pot experiment was conducted to investigate the effects of UV-B radiation on sensitive index (SI) synthetically formed by the height, leaf area and biomass, and on the accumulation of rosmarinic acid (RA) and salvianolic acid B (SAB) of Salvia miltiorrhiza in two growth periods. The results showed the SI in the shoot vigorous growth and harvesting periods both decreased with the increasing UV-B radiation, but the SI in the latter period was even less. The RA and SAB contents in the leaves increased with the increasing UV-B radiation, and the increment was greater in the harvesting period than in the shoot vigorous growth period. The RA and SAB contents decreased in the roots, and decreased with the increasing UV-B intensity and duration. Total contents of RA and SAB in roots decreased to 10.0% and 6.3% of the control under the high UV-B intensity in the harvesting period.


Patent
Tianjin Tasly Pharmaceutical Co. | Date: 2012-02-08

The present invention relates to a new compound of salvianolic acid L, its preparation method, a pharmaceutical composition containing the salvianolic acid L, and its use for preparing a medicament for treating cardio-cerebrovascular diseases.


Patent
Tianjin Tasly Pharmaceutical Co. | Date: 2010-03-29

The present invention relates to a new compound of salvianolic acid L, its preparation method, a pharmaceutical composition containing the salvianolic acid L, and its use for preparing a medicament for treating cardio-cerebrovascular diseases.


Patent
Tianjin Tasly Pharmaceutical Co. | Date: 2010-04-07

The present invention relates to methods for preparing a pharmaceutical composition for treating diabetes mellitus and the pharmaceutical composition prepared by the methods. The pharmaceutical composition of the present invention comprises extracts of the following crude drugs: 5-40 weight parts of Radix Trichosanthis (Tianhuafen), 10-30 weight parts of Radix Bupleuri (Chaihu), 3-15 weight parts of Fructus Aurantii Immaturus (Zhishi), 1-6 weight parts of Radix et Rhizoma Rhei (Dahuang), 1-12 weight parts of Rhizoma Pinelliae (Banxia), 3-15 weight parts of Radix Scutellariae (Huangqin), 1-12 weight parts of Rhizoma Coptidis (Huanglian), 3-15 weight parts of Radix Paeoniae Alba (Baishao) and 5-20 weight parts of Fructus Mume (Wumei), and optionally comprises pharmaceutically acceptable excipient. Also, the pharmaceutical composition of the present invention can further comprise Fructus Crataegi (Shanzha). Additionally, the present invention discloses four methods for preparing the pharmaceutical composition.

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