Shi G.-x.,Capital Medical University |
Liu C.-z.,Capital Medical University |
Guan W.,Tianjin University of Traditional Chinese Medicine |
Wang Z.-k.,Tianjin University of Traditional Chinese Medicine |
And 5 more authors.
Chinese Journal of Integrative Medicine | Year: 2013
Objective: To study the effects of acupuncture on Chinese medicine syndromes of vascular dementia (VaD). Methods: Sixty-three VaD patients were divided into three groups. Those willing to be randomized were randomly assigned to receive either acupuncture (random acupuncture group, 24 cases) or rehabilitation training (guided rehabilitation group, 24 cases) for 6 weeks. Those unwilling to be randomized also received acupuncture for 6 weeks (non-random acupuncture group, 19 cases). Patient syndromes and their severity were evaluated before treatment (baseline), at the end of treatment, and at 4-week follow-up after the completion of treatment using a CM scoring system (scale of differentiation of syndromes of vascular dementia, SDSVD). The SDSVD scores of the random and non-random acupuncture groups, and of all patients who received acupuncture (combined acupuncture group, 43 cases), were compared with those in the guided rehabilitation group. Results: In the random, non-random, and combined acupuncture groups, SDSVD scores were significantly reduced at the end of treatment and at follow-up than at baseline. In the guided rehabilitation group, SDSVD scores were similar to baseline scores at the end of treatment and at follow-up. However, there were no significant differences in SDSVD scores among the three groups or between the combined acupuncture group and the guided rehabilitation group at any time points. In the non-random and combined acupuncture groups, SDSVD scores were significantly reduced at the end of treatment than at baseline in patients with hyperactivity of Liver (Gan)-yang or phlegm obstruction of the orifices. Conclusions: Acupuncture reduced the severity of VaD. The improvement was the greatest in patients undergoing their treatment of choice. Treatments in this study were more effective for excess syndromes, such as Liver-yang hyperactivity or phlegm obstruction of the orifices than deficiency syndromes, such as Kidney (Shen)-essence deficiency. © 2013 Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg.
Liu H.-Y.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine |
Wang X.-J.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine |
Zhang S.,Traditional Chinese Medicine Hospital of Tianjin |
Yang K.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine |
Yu L.,Tianjin University of Traditional Chinese Medicine
World Chinese Journal of Digestology | Year: 2015
AIM: To assess the value of combined detection of serum pepsinogen (PG) and MG-Antigen7- Ag (MG7-Ag) in the diagnosis of precancerous lesions of gastric cancer (PLGC). METHODS: The study included 102 patients with digestive tract symptoms who sought medical treatment at Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital. According to endoscopic and pathological results, the patients were divided into two groups, 65 patients with PLGC and 37 with benign lesions. Additionally, 30 healthy volunteers were included in a normal control group. These three groups were subjected to PG I, PG II, PGR and MG7-Ag detection tests. Using endoscopic and pathology results as a standard, the correlation of PG and MG7-Ag with gastric lesions was determined. RESULTS: Compared with the normal control group and benign gastric lesion group, serum PGI and PGR levels were significantly reduced (P < 0.05), and PGII and MG7-Ag levels were significantly increased (P < 0.05) in the PLGC group. The sensitivity of combined detection of serum PG and MG7-Ag in the diagnosis of PLGC was 92.3%, which was significantly higher than those of single tumor marker (TM) detection; and the specificity was 90.0%, which was not significantly different from those of single TM detection. CONCLUSION: The combined detection of PG and MG7-Ag in the diagnosis of PLGC has high sensitivity, good specificity, and can be used as a good index for screening of PLGC. © 2015 Baishideng Publishing Group Inc. All rights reserved.
Liu H.-Y.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine |
Zhang B.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine |
Jiang L.-G.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine
World Chinese Journal of Digestology | Year: 2013
AIM: To assess the clinic efficacy of Pudilan Oral Solution combined with triple therapy (rabeprazole sodium, clarithromycin and levofloxacin hydrochloride) in eradicating Helicobacter pylori (H. pylori). METHODS: One hundred and twenty-nine patients who were diagnosed with H. pylori infection by rapid urease test or 14C breath test from April 2012 to February 2013 were included in this study and randomly divided into either a control group or a treatment group. The control group was orally given 10 mg of rabeprazole sodium enteric-coated capsules, twice daily, 500 mg of clarithromycin extended-release tablets, twice daily, and 0.4 g of levofloxacin hydrochloride tablets, twice daily. The treatment group was additionally given 10 mL of Pudilan Oral Solution, twice daily. The patients in both groups were treated for 14 d. Clinical efficacy was assessed 30 d after the end of treatment. RESULTS: Both intention-to-treat (ITT) analysis and per-protocol (PP) analysis revealed that the rates of H. pylori eradication were significantly higher in the combination group than in the control group (ITT: 71.4% vs 51.5%; PP: 73.8% vs 55.7%, both P < 0.05). The rate of symptom improvement was also significantly higher in the treatment group than in the control group, although there was no significant difference in the incidence of adverse events between the two groups. CONCLUSION: Pudilan Oral Solution combined with triple therapy has significantly higher rates of H. pylori eradication and clinical symptom improvement than triple therapy alone, although there is no significant difference in the incidence of adverse events between the two therapies. © 2013 Baishideng. All rights reserved.
Xie Y.-Q.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine |
Nie Z.-H.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine |
Liu D.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine |
Feng W.-L.,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine
Journal of Clinical Dermatology | Year: 2014
Objective: To analyse the therapeutic effect of 1% pimecrolimus cream for the treatment of patients with corticosteroid-dependent dermatitis.Methods: Questionnaires were used to record clinical informations of the patients with corticosteroid-dependent dermatitis. All patients consistent with the inclusion criteria of the study were randomly divided into treatment group and control group. The treatment group were given topical 1% pimecrolimus cream twice a day and 10 mg clarityne once a day, meanwhile the control group were given 10 mg clarityne once a day. The course of treatment was 4 weeks. The therapeutic effect and adverse reactions were evaluated after treatment.Results: Among the 196 patients with corticosteroid-dependent dermatitis, the ratio of male to female was 14.43. The facial central type was the most common in the clinical classification (5255%). Compound dexamethasone acetate ointment was the most commonly used topical corticosteroid preparation(3929%), which was usually bought by the patients themselves. After treatment of 4 weeks, the effective rate of treatment group was higher than that of the control group (86.21%vs25%), the difference was statistically significant (χ2 = 5388, P<0.01).Conclusion: Corticosteroid-dependent dermatitis is mainly caused by abuse or misuse of topical corticosteroids, the fundamental reason is due to the insufficient knowledge of how to use corticosteroid preparation rightly. Wo pimecrolimus cream is safe and effective for the treatment of corticosteroid-dependent dermatitis.