Entity

Time filter

Source Type

Papanasam, India

Ramachandran E.,Thiruvalluvar College | Ramukutty S.,Thiruvalluvar College
Journal of Crystal Growth | Year: 2014

The crystal growth of diclofenac acid in silica gel is the first to be reported in literature. The growth parameters were varied to optimize the suitable growth condition. Single crystal X-ray diffraction method was used for the conformation of the crystal structure. Morphology studies showed that the growth is prominent along the b-axis and the prominent face is {002}. Fourier transform infrared spectral study was performed to identify the functional groups present in the crystal. Thermal stability and decomposition of the material were analyzed using thermo calorimetry in the temperature range 30-500 C. © 2013 Published by Elsevier B.V. Source


Ramukutty S.,Thiruvalluvar College | Ramachandran E.,Thiruvalluvar College
Journal of Crystal Growth | Year: 2012

Single crystals of metronidazole were crystallized by the slow solvent evaporation method and used as seeds to grow bulk crystals of size 8.0×6.5×2.0 mm 3 using top-seeded submerged solution growth. The crystals were characterized using single crystal X-ray diffraction. Fourier transform infrared spectral analysis was made for the absorption bands of various functional groups present in the crystal. UV-vis absorption spectrum was used to identify the presence of nitroimidazole in metronidazole. Morphology study revealed that the growth is prominent along the c-axis and the prominent face is {010}. Thermal stability and thermal decomposition were analyzed using thermo calorimetry. © 2012 ElsevierB.V. All rights reserved. Source


Ramukutty S.,Thiruvalluvar College | Ramachandran E.,Thiruvalluvar College
Crystal Research and Technology | Year: 2012

RS -Ibuprofen was crystallized for the first time in silica gel under suitable pH conditions by reduction of solubility method. The grown crystals were characterized by single crystal X-ray diffraction and density measurement. The functional groups present in the crystal were identified using Fourier transform infrared spectroscopy. Optical bandgap energy of ibuprofen was estimated as 3.19(3) eV from UV-Vis spectrum. Thermogravimetric analysis revealed that ibuprofen is thermally stable upto 102.9 °C and the initial loss of mass was due to evaporation only. Morphological study showed that the growth is prominent along b-axis and the prominent face is {100}. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source


Ramukutty S.,Thiruvalluvar College | Jeyasudha R.,Thiruvalluvar College | Ramachandran E.,Thiruvalluvar College
Indian Journal of Physics | Year: 2013

Single crystals of metronidazole have been synthesized natural evaporation method. The grown crystal has been confirmed using single crystal X-ray diffraction analysis. Mechanical behavior has been determined using Vickers hardness measurement. Work-hardening coefficient and Newtonian resistance pressure of the crystal have been estimated. Kinetic analysis of the thermogravimetric data has been carried out by using Coats-Redfern relation. Activation energy, frequency factor and order of reaction have been also calculated. The Arrhenius equation for metronidazole is k = 0.38 × 108 e-76.679/RT mol-1 s-1. Thermodynamic parameters have been also determined. © 2013 Indian Association for the Cultivation of Science. Source

Discover hidden collaborations