Ann Arbor, CA, United States

The University of West Los Angeles
Ann Arbor, CA, United States

The University of West Los Angeles - School of Law is a private, for-profit law school. It maintains two campuses in the Los Angeles metropolitan area in Inglewood and Chatsworth (San Fernando Valley}. The School of Law is accredited by the State Bar of California Committee of Bar Examiners. Wikipedia.

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Islam M.A.,The University of West Los Angeles | Gunaseelan S.,The University of West Los Angeles
Current Nutrition and Food Science | Year: 2014

Quercetin, a widely occurring plant flavonoid, is well-known for its antioxidant activity. A great deal of research in the form of animal and cell culture studies has been performed over the last 30 years, as well as a few clinical studies in human populations; however, its specific effects on various contributing factors to cardiovascular disease are not fully understood. This review seeks to summarize many of the latest studies regarding the effects of quercetin on cardiovascular health. Overall, the research reflects positive effects of quercetin on atherosclerosis, hypertension, dyslipidemia and endothelial function. However, in vivo studies have shown that quercetin imparts varying plasma levels due to its poor aqueous solubility and low stability in biological fluids. Research efforts are currently being devoted to overcome these limitations by designing and testing modified forms of quercetin or improved formulations which provide enhanced bioavailability and higher efficacy. The development of improved dosage forms for in vivo administration of quercetin and well-designed clinical studies are warranted for further evaluation of the effects of quercetin on cardiovascular health. © 2014 Bentham Science Publishers.

PubMed | The University of West Los Angeles, University of Texas at Tyler and Lake Erie College
Type: Journal Article | Journal: Advances in physiology education | Year: 2016

The purpose of the present study was to assess the current status of physiology education in US Doctor of Pharmacy (PharmD) programs. A survey instrument was developed and distributed through SurveyMonkey to American Association of Colleges of Pharmacy (AACP) Biological Sciences section members of 132 PharmD programs. Survey items focused on soliciting qualitative and quantitative information on the delivery of physiology curricular contents and faculty perceptions of physiology education. A total of 114 programs responded to the survey, resulting in a response rate of 86%. Out of 114 schools/colleges, 61 programs (54%) offered standalone physiology courses, and 53 programs (46%) offered physiology integrated with other courses. When integrated, the average contact hours for physiology contents were significantly reduced compared with standalone courses (30 vs. 84 h, P < 0.0001). Survey respondents identified diverse strategies in the delivery and assessment of physiology contents. Eighty percent of the responding faculty (n = 204) agree/strongly agree that physiology is underemphasized in PharmD curriculum. Moreover, 67% of the respondents agree/strongly agree that physiology should be taught as a standalone foundational course. A wide variation in the depth and breadth of physiology course offerings in US PharmD programs remains. The reduction of physiology contents is evident when physiology is taught as a component of integrated courses. Given current trends that favor integrated curricula, these data suggest that additional collaboration among basic and clinical science faculty is required to ensure that physiology contents are balanced and not underemphasized in a PharmD curriculum.

Kim N.,The University of West Los Angeles | Boone K.B.,Alliant International University | Victor T.,California State University, Dominguez Hills | Lu P.,University of California at Los Angeles | And 2 more authors.
Archives of Clinical Neuropsychology | Year: 2010

Recently published practice standards recommend that multiple effort indicators be interspersed throughout neuropsychological evaluations to assess for response bias, which is most efficiently accomplished through use of effort indicators from standard cognitive tests already included in test batteries. The present study examined the utility of a timed recognition trial added to standard administration of the WAIS-III Digit Symbol subtest in a large sample of "real world" noncredible patients (n=82) as compared with credible neuropsychology clinic patients (n=89). Scores from the recognition trial were more sensitive in identifying poor effort than were standard Digit Symbol scores, and use of an equation incorporating Digit Symbol Age-Corrected Scaled Scores plus accuracy and time scores from the recognition trial was associated with nearly 80 sensitivity at 88.7 specificity. Thus, inclusion of a brief recognition trial to Digit Symbol administration has the potential to provide accurate assessment of response bias. © The Author 2010. Published by Oxford University Press. All rights reserved.

Falender C.A.,The University of West Los Angeles | Shafranske E.P.,The University of West Los Angeles | Ofek A.,University of California at Los Angeles
Counselling Psychology Quarterly | Year: 2014

With the recognition that clinical supervision is a distinct professional practice comes the necessity for identification of effective practices. In this competency-based era, a meta-theoretical, interpersonal framework is provided in competency-based clinical supervision in which specific attention is paid to the strengths and emerging competencies of the supervisee and to the clinical and supervision competencies of the supervisor. In this article, the authors address the state of the literature on effective clinical supervision and the specific knowledge, skills, and attitudes that comprise competent supervision. A brief summary of research on several particular pivotal areas (e.g. alliance, multicultural competence, legal, and ethical issues) is included. A self-assessment device is provided for both current supervisors and supervisors-in-preparation to assess readiness, competence, and areas in which additional training and experience are desirable. Finally, a vignette illustrating the implementation of effective supervision practices is provided. © 2014 Taylor & Francis.

PubMed | The University of West Los Angeles, University of Sichuan and University of California at Los Angeles
Type: Journal Article | Journal: Neuron | Year: 2016

Normal breathing in rodents requires activity of glutamatergic Dbx1-derived (Dbx1(+)) preBtzinger Complex (preBtC) neurons expressing somatostatin (SST). We combined invivo optogenetic and pharmacological perturbations to elucidate the functional roles of these neurons in breathing. In transgenic adult mice expressing channelrhodopsin (ChR2) in Dbx1(+) neurons, photoresponsive preBtC neurons had preinspiratory or inspiratory firing patterns associated with excitatory effects on burst timing and pattern. In transgenic adult mice expressing ChR2 in SST(+) neurons, photoresponsive preBtC neurons had inspiratory or postinspiratory firing patterns associated with excitatory responses on pattern or inhibitory responses that were largely eliminated by blocking synaptic inhibition within preBtC or by local viral infection limiting ChR2 expression to preBtC SST(+) neurons. We conclude that: (1) preinspiratory preBtC Dbx1(+) neurons are rhythmogenic, (2) inspiratory preBtC Dbx1(+) and SST(+) neurons primarily act to pattern respiratory motor output, and (3) SST(+)-neuron-mediated pathways and postsynaptic inhibition within preBtC modulate breathing pattern.

Yu D.D.,Beckman Research Institute | Sousa K.M.,Beckman Research Institute | Sousa K.M.,The University of West Los Angeles | Mattern D.L.,University of Mississippi | And 5 more authors.
Bioorganic and Medicinal Chemistry | Year: 2015

GP-BAR1 (also known as TGR5), a novel G-protein coupled receptor regulating various non-genomic functions via bile acid signaling, has emerged as a promising target for metabolic disorders, including obesity and type II diabetes. However, given that many bile acids (BAs) are poorly tolerated for systemic therapeutic use, there is significant need to develop GP-BAR1 agonists with improved potency and specificity and there also is significant impetus to develop a stereoselective synthetic methodology for GP-BAR1 agonists. Here, we report the development of highly stereo-controlled strategies to investigate a series of naturally occurring bile acid derivatives with markedly enhanced GP-BAR1 activity. These novel GP-BAR1 agonists are evaluated in vitro using luciferase-based reporter and cAMP assays to elucidate their biological properties. In vivo studies revealed that the GP-BAR1 agonist 23(S)-m-LCA increased intestinal GLP-1 transcripts by 26-fold. Additionally, computational modeling studies of selected ligands that exhibit enhanced potency and specificity for GP-BAR1 provide information on potential binding sites for these ligands in GP-BAR1. © 2015 Elsevier Ltd. All rights reserved.

Thomas H.,The University of West Los Angeles
Topics in Geriatric Rehabilitation | Year: 2016

This article describes the case of a 69-year-old, married, Hispanic heterosexual woman who suffered a right cerebral vascular accident. Assessment measures utilized to identify barriers to sexual activity were the Canadian Occupational Performance Measure, Quality of Sexual Function Scale, and the Stroke Impact Scale. Goals were established in collaboration with the client, and interventions addressed a wide range of barriers. This case demonstrates how occupational therapy and the interprofessional team addressed limitations in engagement in sexual activities. Data collected postintervention showed significant changes in sexual activity, satisfaction, and perceived quality of life. This case demonstrates the importance of addressing sexual activity with clients poststroke and how the health care team can implement strategies to help clients address barriers to this essential human activity. Copyright © 2016 Wolters Kluwer Health, Inc.

Matley B.G.,Ventura College | Matley B.G.,The University of West Los Angeles
Proceedings - IEEE Symposium on Security and Privacy | Year: 2012

American history and custom are rich with the sense of personal privacy. That sense of privacy remained so strong that when the computer became reality in daily government operations, concerns about preserving privacy were vigorously expressed. The Congressional hearings on the National Data Bank(NDB) proposal of the 1960s is illustrative. In the end, the proposal was not funded out of concern for the massive volume of personal data to be contained, transmission of it around the country in telecommunications networks not secure, a national ID system that might emerge, and computer matching schemes to follow. Today, our computer practices sometimes violate those earlier tenets on computers and privacy. Some government networks now contain more personal data than waa proposed for the NDB; networks are not secure, even subject to penetration by hackers; a national ID system has been proposed, but SSN ia one in effect; matching schemes for draft registration verification and debt collection by the Internal Revenue Service on behalf of other agencies, do work. Computer practices in conflict with privacy principles raise the spectre of extra-Constitutional government in America, and leave us with crucial policy choices in computing. © 1985 IEEE.

Nelson L.C.,The University of West Los Angeles | Ryan L.J.,The University of West Los Angeles
Medical Acupuncture | Year: 2014

Background: One in every 4 deaths in the United States is from heart disease. Coronary heart disease alone in the United States costs $108.9 billion each year, including both direct and indirect costs. Objective: The purpose of this research was to identify factors present in scientific studies related to acupuncture use as a treatment for cardiovascular disease. Methods: A pool of 109 studies were considered for inclusion in the current study. Using a literature review synthesis method, 54 articles qualified for inclusion and were reviewed. Using grounded theory, open and axial coding procedures data were generated from the 54 studies that were reviewed. Results: Three clusters/factors relating to the use of acupuncture to prevent and treat cardiovascular disorders emerged from the data. The identified clusters included: (1) interactions between meridian systems and the PC 6 acupuncture point; (2) the interactions of the brain, pain, and opioids; and (3) the interactions of nitric oxide, heart performance, and cardiomyocytes. Conclusions: Acupuncture should be considered as a preventative measure against, and treatment for, heart disease. Western and Eastern practitioners should collaborate to achieve more-efficient and effective care of patients who are experiencing cardiovascular dysfunction. © Mary Ann Liebert, Inc. 2014.

Duley S.I.,The University of West Los Angeles
Journal of dental hygiene : JDH / American Dental Hygienists' Association | Year: 2012

The need for education about oral health conditions has been discussed in recent years. Current research has shown correlations between oral and systemic disease. Disease entities have been connected to bacteremia and inflammatory process es, both of which can result from oral pathologies. Professionals need to be educated about these connections and advised how, by maintaining proper oral health, they may avoid systemic consequences. Students in dental hygiene, health care management and nursing programs can play a vital role in this education. By jointly creating and operating an educational Center for Oral Health Promotion, they can better understand each other's professions. This will facilitate developing the skill set to reach out to the underserved and establish protocols to provide health literacy and care at affordable rates. They can also better appreciate the interconnections between health care delivery and its management while gaining skills needed to work in an inter-professional setting. A Center for Oral Health Promotion would expand services typically offered in dental hygiene educational settings as well as expand dental hygiene, nursing and health care management student experiences.

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