Al Maniri A.,Sultan Qaboos University |
Al Maniri A.,The Research Council |
Coomber B.L.,University of Guelph
Journal of Histochemistry and Cytochemistry | Year: 2014
The mechanism by which neuropilin-1 (NRP-1) induces malignancy in Epithelial Ovarian Cancer (EOC) is still unknown. This study is the first to demonstrate the relationship between NRP-1 expression and EMT markers vimentin, N-cadherin, E-cadherin and Slug. We used tissue microarrays containing the three main subtypes of EOC tumors: serous, mucinous cystadenocarcinoma and endometrioid adenocarcinoma and representative cases retrieved from our pathology archives. Immunohistochemistry was performed to detect the expression levels and location of NRP-1 and the aforementioned EMT proteins. NRP-1 was mainly expressed on cancer cells but not in normal ovarian surface epithelium (OSE). The Immunoreactive Scoring (IRS) values revealed that the expression of NRP-1, Slug and E-cadherin in the malignant subtypes of ovarian tissues was significantly higher (5.18 ± 0.64, 4.84 ± 0.7, 4.98 ± 0.68, respectively) than their expression in the normal and benign tissues (1.04 ± 0.29, 0.84 ± 0.68, 1.71 ± 0.66, respectively), with no significant differences among the studied subtypes. Vimentin was expressed in the cancer cell component of 43% of tumors and it was exclusively localized in the stroma of all mucinous tumors. The Spearman’s rho value indicated that NRP-1 is positively related to the EMT markers E-cadherin and Slug. This notion might indicate that NRP-1 is a partner in the EMT process in EOC tumors. © The Author(s) 2014.
Agency: European Commission | Branch: FP7 | Program: CSA-CA | Phase: INCO-2009-1.1 | Award Amount: 2.62M | Year: 2010
INCONET-GCC aims to develop and support the bi-regional dialogue by bringing together policymakers and stakeholders of the GCC and EU Member States. It aims to create a dialogue and action platform to identify common interests in research areas, set up S&T priorities, support capacity building activities, and enhance the interaction between different cooperation instruments of the EC and EU Member States. It will promote actions in order to monitor, develop, promote and contribute to the creation of synergies among the various S&T cooperation programmes between the GCC and the EU Member States, and foster the participation of the GCC in the FP7, CIP, etc. An observatory of EU-GCC cooperation in S&T will be created in the project framework. The main outputs of INCONET-GCC will be INCONET-GCC open networking platform for policy dialogue and the future S&T, Contribution of INCONET-GCC to the EU Strategic Framework for International Cooperation is S&T, Collaborative plan in S&T policy advisory contributing to the decisions of the GCC-EU Joint Council, INCONET-GCC White Paper, Integration of GCC NCPs with EU NCP network, INCONET-GCC roadmap and sustainability report, Organisation of International Conference and dissemination events. INCONET-GCC will be achieved through a high quality, recognized value and expertise consortium. Consortium roles and expertise are complementary and allows for a balanced effort allocation across its the different objectives. Partners coming from distinguished institutions in EU and GCC region and includes representatives of all countries of the Arabian Peninsula, which politically includes the 6 GCC states and Yemen, which repeatedly seeks to join the GCC six-country block. The Ministry of Education (Egypt) and the Ministry of Higher Education (Morocco) are MIRA partners that will act as the liaison with MIRA project and their cultural background is close to those of GCC region. The consortium is flexible and easily manageable.
Agency: European Commission | Branch: FP7 | Program: CSA-CA | Phase: INCO.2013-1.1 | Award Amount: 2.35M | Year: 2014
INCONET-GCC2s overall goal is to support the institutional bi-regional policy dialogue in Science, Technology and Innovation, to strengthen the bi-regional cooperation between research and innovation actors, especially in the context of the upcoming Horizon 2020 programme and finally to monitor progress in the bi-regional STI cooperation. INCONET-GCC2 builds on the results of previous cooperation activities with the Arab Gulf Countries (INCONET-GCC 1st phase, www.icnonet-gcc.eu) while it focuses on selected societal challenges of mutual interest as identified during the previous collaboration. INCONET-GCC2 explores now to achieve win-win across national, multidisciplinary and cross-sectoral approaches can be spurred in response to these issues while also realising and underpinning new pathbreaking kinds of capacity-building and organising clustering activities around the selected research priorities. Specifically: (1) Implement a series of analyses feeding the policy dialogue and increasing its efficiency, monitoring INCONET-GCC2s own activities, with particular emphasis on their sustainability, and implementing coherent dissemination activities in order to increase its visibility and impact; (2) Built of best practices towards the future in order to promote joint research though clustering activities within the selected societal challenges and organise thematic workshops in Health, Energy, Innovation and Security and ICT, Food towards EU-GCC Joint Call for proposals; (3) Enhance capacity building through the delivery of the facilitation of researcher mobility, summer schools, the support of the NCPs and their expansion in order to cover the selected societal challenges and the organisation of information days and brokerage events in all Arab Gulf countries; (4) Roadmap future research activities and provide recommendations to the EC and the national regulatory and funding authorities; (5)Raise awareness and disseminate information.
News Article | February 21, 2017
STAMFORD, Conn. & OSLO, Norway--(BUSINESS WIRE)--Sonitor Technologies Inc., a global leader in indoor positioning technologies, announced today that The Research Council of Norway (RCN – www.rcn.no) has selected Sonitor Technologies and MazeMap (www.mazemap.com) as one of the winners in the latest round of research innovation awards. http://www.forskningsradet.no/no/Nyheter/Forskningsradet_har_delt_ut_900_millioner_til_innovasjon_i_neringslivet/1254024689778/p1174467583739 This funding award recognizes the world-class innovative power of both companies in the field of indoor positioning. The goal of the project is to develop a new generation of indoor positioning technology that will place accurate and cost-effective 3D positioning in everyone’s hands. To achieve this, both companies will work collaboratively with leading research groups at the University of Oslo led by Professor Sverre Holm and Associate Professor Jan Kenneth Bekkeng. “We’re very excited to partner with MazeMap and collaborate with the University of Oslo on this project and honored to be selected by RCN,” said Wilfred Booij, CTO at Sonitor Technologies. “By combining Sonitor’s proprietary ultrasound indoor positioning expertise and technology with MazeMap’s indoor maps and wayfinding expertise, we have the unique opportunity to bring next generation, innovative 3D positioning to consumers in many markets.” Sonitor is the leading developer and provider of unique, ultrasound-based indoor positioning technology that locates people and items in real time with reliable, high definition accuracy within complex indoor environments. Sonitor has developed the healthcare industry’s most advanced open integration RTLS platform, Sonitor Sense™, a wireless system which supports a wide range of applications to make hospital operations more efficient. Sonitor is selected by world-class partners to build industry-leading solutions for global deployment. For more information please visit www.sonitor.com. About The Research Council of Norway The Research Council of Norway serves as the chief advisory body for the Norwegian government on research policy issues. It distributes roughly nine billion Norwegian Kroner (NOK) (approximately 1 billion US Dollars) to research and innovation activities each year and works to promote international cooperation and increase participation in the EU framework program on research and innovation. The Research Council creates meeting places and provides a platform for dialogue between researchers, users of research and research funders.
Al-Azri M.,Sultan Qaboos University |
Al-Ramadhani R.,Ministry of Health |
Al-Rawahi N.,Ministry of Health |
Al-Shafee K.,Sultan Qaboos University |
And 2 more authors.
Family Practice | Year: 2014
Background: Relational continuity is a cornerstone of primary care. In developing countries, however, little research has been conducted to determine the perception and experiences of patients in view of relational continuity in primary care. Objective: To study the role of relational continuity in primary care settings and its effect on patients' perceptions and experiences. Methods: A questionnaire-based survey was conducted at eight primary care health centres (PCHCs) in Al-Seeb province, Muscat, the capital city of Oman. All Omani patients aged 18 years and above attending their PCHCs during the study period were invited to participate in the study. Results: From a total of 1300 patients invited, 958 Omani patients agreed to participate in the study (response rate = 74%). More than half of the patients (61%) expressed the preference of consulting the same primary care physician (PCP) to whom they were accustomed. This increased to 69% if the patients had psychosocial problems and to 71% if the patients had chronic medical conditions. A significant proportion of the respondents (72%) felt comfortable and relaxed when consulting the same PCP and 67% expressed an interest in maintaining continuity with the same PCP. The general perspective held by the majority of the studied patients (61%) indicated that relational continuity improved both the patients' medical conditions (51%) and the quality of services (61%). In actuality, however, only 18% experienced relational continuity in their PCHCs. The preference for relational continuity was significantly increased among patients who identified a favourite PCP (P = 0.029) and among educated patients (P = 0.023). Conclusion: Although it is relatively difficult to consult with the same PCP, the majority of Omani patients have experienced several benefits from relational continuity within the context of patient-physician relationship. The preference for relational continuity was highly expressed by patients with chronic or psychosocial problems, patients who were educated and those who identified a named PCP. In view of these findings, the basis of relational continuity if progressed, a great effort is needed to develop and implement strategies to promote relational continuity in primary health care in Oman. © The Author 2014. Published by Oxford University Press. All rights reserved.
News Article | October 28, 2016
PENETRON Specialty Products (PSP) welcomed distributors and installers on October 4th and 5th to the PSP manufacturing facility in Allentown, PA, for the Fall Product Research Council event, a bi-annual event and an important part of the company’s ongoing product innovation efforts. “This event brought together a number of high-level distributors and installers, creating a platform to exchange market and product information. This also provided an opportunity for the attendees to use all our products and see first-hand how well they perform,” says Peter Trainor, Vice President of Sales at PENETRON Specialty Products. “We covered all of our products, which gave them a greater awareness of the bandwidth of PSP. What was once a two-product company has grown to a full range of floor prep and concrete repair solutions.” Part of the PENETRON Group of global companies, PSP is a recognized developer and manufacturer of surface preparation and concrete restoration products. The PSP network of technical and sales support works with customers to ensure the best results for each project. The Research Council events – held every year in the spring and fall – are a key part of PSP’s technical support and product development efforts. The Fall Product Research Council was a 1 ½-day program that included the following highlights: Product demonstrations and hands-on evaluation of new products and materials were done by the attendees together with PSP technical support experts. The demos were followed by numerous and far-ranging discussions on the product features and benefits – and how these best meet project needs. During the discussions, customers learned about the newest product development efforts and also contributed their input on everything from packaging to performance and new applications. “The opinions and advice on our products from the attendees is invaluable for improving PSP products and determining new or unmet needs for all of our floor prep and concrete repair products,” adds Robert Baumeister, Technical Support Manager at PSP. “Finally, because the event venue is also our manufacturing plant, customers can witness up close how our products are manufactured and packaged,” adds Mr. Trainor. “In this last session, we gained some important feedback on the packaging for one of our products on the first day – and the improved product packaging was rolling off the line before they left for home the next day. That’s what we like to call customer support!” PSP will host its next Product Research Council event in March 2017. Please contact Peter Trainor, ptrainor(at)penetronsp(dot)com, for more information. The PENETRON Group is a leading manufacturer of specialty construction products for concrete waterproofing, concrete repairs and floor preparation systems. The Group operates through a global network, offering support to the design and construction community through its regional offices, representatives and distribution channels. For more information on PENETRON waterproofing solutions, please visit penetron.com or Facebook.com/ThePenetronGroup, email CRDept(at)penetron(dot)com, or contact the Corporate Relations Department at 631-941-9700.
Al-Anqudi S.M.,Sultan Qaboos University |
Al-Sudairy S.,Sultan Qaboos University |
Al-Hosni A.,Petroleum Development Oman |
Al-Maniri A.,The Research Council
Sultan Qaboos University Medical Journal | Year: 2014
Objectives: The aim of this retrospective study was to investigate the prevalence and pattern of third molar impaction in patients between 19-26 years old attending Sultan Qaboos University Hospital (SQUH) in Muscat, Oman. Methods: The study reviewed 1,000 orthopantomograms (OPGs) of patients attending the Oral Health Department of SQUH between October 2010 and April 2011. Patients were evaluated to determine the prevalence of third molar impaction, angulation, level of eruption and associated pathological conditions. Results: Of the study population, 543 (54.3%) OPGs showed at least one impacted third molar. The total number of impacted molars was 1,128. The most common number of impacted third molars was two (41%). The most common angulation of impaction in the mandible was the mesioangular (35%) and the most common level of impaction in the mandible was level A. Of the 388 bilateral occurrences of impacted third molars, 377 were in the mandible. There was no significant difference in the frequency of impaction between the right and left sides of both jaws. Pathological conditions associated with impacted lower third molars were found in 18%, of which 14% were associated with a radiographic radiolucency of more than 2.5 mm, and 4% of impacted lower third molars were associated with dental caries. Conclusion: This study found that more than half of Omani adult patients ranging in age from 19-26 years had at least one impacted third molar.
Al-Sadi A.M.,Sultan Qaboos University |
Al-Mazroui S.S.,The Research Council |
Phillips A.J.L.,New University of Lisbon
Journal of Applied Microbiology | Year: 2015
Aims: Potting media and organic fertilizers (OFs) are commonly used in agricultural systems. However, there is a lack of studies on the efficiency of culture-based techniques in assessing the level of fungal diversity in these products. A study was conducted to investigate the efficiency of seven culture-based techniques and pyrosequencing for characterizing fungal diversity in potting media and OFs. Methods and Results: Fungal diversity was evaluated using serial dilution, direct plating and baiting with carrot slices, potato slices, radish seeds, cucumber seeds and cucumber cotyledons. Identity of all the isolates was confirmed on the basis of the internal transcribed spacer region of the ribosomal RNA (ITS rRNA) sequence data. The direct plating technique was found to be superior over other culture-based techniques in the number of fungal species detected. It was also found to be simple and the least time consuming technique. Comparing the efficiency of direct plating with 454 pyrosequencing revealed that pyrosequencing detected 12 and 15 times more fungal species from potting media and OFs respectively. Analysis revealed that there were differences between potting media and OFs in the dominant phyla, classes, orders, families, genera and species detected. Zygomycota (52%) and Chytridiomycota (60%) were the predominant phyla in potting media and OFs respectively. Conclusions: The superiority of pyrosequencing over cultural methods could be related to the ability to detect obligate fungi, slow growing fungi and fungi that exist at low population densities. Significance and Impact of the Study: The evaluated methods in this study, especially direct plating and pyrosequencing, may be used as tools to help detect and reduce movement of unwanted fungi between countries and regions. © 2015 The Society for Applied Microbiology.
Al-Mazroui S.S.,The Research Council |
Al-Sadi A.M.,Sultan Qaboos University
International Journal of Agriculture and Biology | Year: 2016
A study was conducted to investigate fungal diversity in organic compost originating from Oman. Analysis of diversity was conducted using 454 pyrosequencing and direct planting. The obtained fungal species through direct plating were identified based on the internal transcribed spacer region of the ribosomal RNA (rRNA). Pyrosequencing detected the presence of 94 fungal species, compared to 5 species detected by direct plating. Pyrosequencing also detected more fungal phyla, classes, orders, families and genera. Most of the detected species belonged to Ascomycota and Chytridiomycota, with Powellomyces spp., Eupenicillium spp. and Chaetomium spp. being the most dominant genera. The majority of the detected species (>99%) were found to be either saprophytic or with biocontrol characteristics, with few species (Fusarium and Phoma), being potential pathogens of plants. The low level of presence of pathogenic species may provide evidence of the health status of the organic compost. The study reports for the first time the occurrence of 67 fungal species in Oman. It discusses the superiority of pyrosequencing over direct plating and the factors influencing diversity of fungi in organic composts. © 2016 Friends Science Publishers.
Al-Azri M.,Sultan Qaboos University |
Al-Rasbi K.,Sultan Qaboos University |
Al-Hinai M.,Sultan Qaboos University |
Davidson R.,Sultan Qaboos University |
Al-Maniri A.,The Research Council
Asian Pacific Journal of Cancer Prevention | Year: 2014
Background: Cancer is the leading cause of mortality around the world. However, the majority of cancers occur as a result of modifiable risk factors; hence public awareness of cancer risk factors is crucial to reduce the incidence. The objective of this study was to identify the level of public awareness of cancer risk factors among the adult Omani population. Materials and Methods: A community based survey using the Cancer Awareness Measure (CAM) questionnaire was conducted in three areas of Oman to measure public awareness of cancer risk factors. Omani adults aged 18 years and above were invited to participate in the study. SPPSS (ver.20) was used to analyse the data. Results: A total of 384 participated from 500 invited individuals (response rate =77%). The majority of respondents agreed that smoking cigarettes (320, 83.3%), passive smoking (279, 72.7%) and excessive drinking of alcohol (265, 69%) are risks factors for cancer. However, fewer respondents agreed that eating less fruit and vegetables (83, 21.6%), eating more red or processed meat (116, 30.2%), being overweight (BMI> 25) (123, 32%), doing less physical exercise (119, 31%), being over 70 years old (72, 18.8%), having a close relative with cancer (134, 34.9%), infection with human papilloma virus (HPV) (117, 30.5%) and getting frequent sunburn during childhood (149, 38.8%) are risk factors for cancer. A significant association was found between participant responses and their educational level. The higher the educational level, the more likely that respondents identified cancer risk factors including smoking (p<0.0005), passive smoking (p= 0.007), excessive drinking of alcohol (p<0.0005), eating less fruit and vegetables (p= 0.001) and infection with HPV (p<0.0005). Conclusions: The majority of respondents in this study in Oman were not aware of the common risk factors for cancer. It may be possible to reduce the incidence of cancers in Oman by developing strategies to educate the public about these risk factors.