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Lu C.,The Peoples Hospital of Huaibei | Xia J.,CAS Shanghai Institutes for Biological Sciences | Wang B.,The Peoples Hospital of Huaibei | Wu Y.,The Peoples Hospital of Huaibei | And 2 more authors.
BioScience Trends | Year: 2015

Traumatic brain injury (TBI) is a main cause of death and disability around the world especially in soldiers, children, and young men. Since its clinical diagnosis and treatment cannot predict its prognosis, novel diagnostic techniques need to be developed, insight into its molecular mechanisms needs to be gleaned, and alternative and complementary medicine (ACM) approaches to its treatment need to be developed. This review summarizes the new diagnostic methods used in clinical practice, such as imaging of structural abnormalities after TBI and measurement of prognosis-related biomarkers. This review also describes the cellular mechanisms of traditional Chinese medicine in terms of intracellular signaling pathways, the extracellular microenvironment, and stem cells. This review concludes by describing experimental and clinical studies of the use of traditional Chinese medicine as a form of ACM to treat TBI. This review helps to understand advances in the field of TBI diagnosis and treatment.

Pan S.-X.,The Peoples Hospital of Huaibei | Tian J.,The Peoples Hospital of Huaibei | Fan F.,The Peoples Hospital of Huaibei | Wang X.-H.,The Peoples Hospital of Huaibei
International Eye Science | Year: 2014

AIM: To observe the clinical effect of stopping and chopping method with manual nucleus extraction in hard nucleus cataract, and also discuss the surgical skills. METHODS: Totally 50 cases (50 eyes) of age-related cataract with above IV grade hard nucleus were randomly divided into two groups, 30 cases (30 eyes) were in observe group which was performed by stopping and chopping method combined with manual nucleus extraction and 20 cases (20 eyes) underwent phacoemulsification as control group, intraocular lenses implantation was performed in two groups. The processing time of nucleus, operative complications, postoperative visual acuity, the condition of corneal edema, intraocular pressure and corneal endothelial cells were observed. RESULTS: The processing time of nucleus of observe group and control group was 60±10s, 90±15s, respectively (P<0.05). Operative complications of the observe group, which were the incidence of posterior capsular rupture, the reaction of corneal edema and the damage of corneal endothelial cells, was less than control group and no statistical significance (P<0.05). The difference of postoperative visual acuity and intraocular pressure was not obvious in two groups. CONCLUSION: Stopping and chopping method combined with manual nucleus extraction in hard nucleus cataract has many virtues of security, faster visual recovery and less complications. It is one of the ideal treatment of age-related cataract with above IV grade hard nucleus.

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