The Ninth Peoples Hospital of Shenzhen City

Shenzhen, China

The Ninth Peoples Hospital of Shenzhen City

Shenzhen, China
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Ren G.,Southern Medical University | Ren G.,Xinjiang Medical University | Li H.,Longgang District Central Hospital of Shenzhen | He X.,The Ninth Peoples Hospital of Shenzhen City | Zhang J.,Southern Medical University
International Journal of Clinical and Experimental Pathology | Year: 2017

Deregulation of miRNAs has been demonstrated to play an important role in the initiation and development of many types of cancers including papillary thyroid carcinoma (PTC). Currently the role of miR-26a and its potential clinical significance for PTC remains unknown. Eighty-four PTC patients and forty healthy controls were enrolled in this study. Quantitative real-time PCR (qRT-PCR) was performed to determine the expression level of serum miR-26a in all the participants. The association between serum miR-26a expression level and clinical outcome of PTC was investigated. Serum miR-26a expression level was reduced in PTC patients compared with the healthy controls (P < 0.01) and significantly increased after receiving treatments (P < 0.01). Serum miR-26a expression level was associated with lymph node metastasis (P=0.0173) and TNM stage (P=0.0022). In addition, PTC with lower serum miR-26a expression had poorer overall (P=0.029) and disease free survival rates (P=0.0004). Moreover, serum miR-26a expression was an independent risk factor for PTC (P < 0.05). Collectively, down-regulation of serum miR-26a is associated with poor prognosis in PTC and it might be a promising biomarker for this malignancy.


Gao Y.,The Ninth Peoples Hospital of Shenzhen City | Jiang A.,The Ninth Peoples Hospital of Shenzhen City | Li B.,The Ninth Peoples Hospital of Shenzhen City | Yang L.,The Ninth Peoples Hospital of Shenzhen City
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology | Year: 2011

OBJECTIVE: To study the effect of piezosurgery in the extraction of mandibular impacted third molars.METHODS: 228 mandibular impacted third molars with relative difficulty for extraction according to the scheme of degree of difficulty for extraction were included in the study, and were divided into two groups (114 teeth each group): Test group (treated by piezosurgery), control group (treated by traditional chisel osteotomy). The surgery time and pain, restriction of mouth opening and facial swelling after surgery, were evaluated in both groups.RESULTS: The average surgery time was (16 +/- 5.2) min in test group and (30 +/- 8.7) min in control group. The surgery time, pain, facial swelling rate, and restriction of mouth opening were lower than control group (P<0.05).CONCLUSION: Compared with traditional chisel osteotomy, the average surgery time with piezosurgery was significantly shorter and the complications are obviously reduced.


PubMed | The Ninth Peoples Hospital of Shenzhen City
Type: Journal Article | Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology | Year: 2011

To study the effect of piezosurgery in the extraction of mandibular impacted third molars.228 mandibular impacted third molars with relative difficulty for extraction according to the scheme of degree of difficulty for extraction were included in the study, and were divided into two groups (114 teeth each group): Test group (treated by piezosurgery), control group (treated by traditional chisel osteotomy). The surgery time and pain, restriction of mouth opening and facial swelling after surgery, were evaluated in both groups.The average surgery time was (16 +/- 5.2) min in test group and (30 +/- 8.7) min in control group. The surgery time, pain, facial swelling rate, and restriction of mouth opening were lower than control group (P<0.05).Compared with traditional chisel osteotomy, the average surgery time with piezosurgery was significantly shorter and the complications are obviously reduced.

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