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Fu Q.,Chinese Academy of Sciences | Fu Q.,Max Planck Institute for Evolutionary Anthropology | Li H.,The Broad Institute of MIT and Harvard | Li H.,Harvard University | And 34 more authors.
Nature | Year: 2014

We present the high-quality genome sequence of a 45,000-year-old modern human male from Siberia. This individual derives from a population that lived before-or simultaneously with-the separation of the populations in western and eastern Eurasia and carries a similar amount of Neanderthal ancestry as present-day Eurasians. However, the genomic segments of Neanderthal ancestry are substantially longer than those observed in present-day individuals, indicating that Neanderthal gene flow into the ancestors of this individual occurred 7,000-13,000 years before he lived. We estimate an autosomal mutation rate of 0.4 × 10-9 to 0.6 × 10-9 per site per year, a Y chromosomal mutation rate of 0.7 × 10-9 to 0.9 × 10-9 per site per year based on the additional substitutions that have occurred in present-day non- Africans compared to this genome, and a mitochondrial mutation rate of 1.8 × 10-8 to 3.2 × 10-8 per site per year based on the age of the bone. © 2014 Macmillan Publishers Limited. All rights reserved.


Dernovoy B.F.,The Ministry of Internal Affairs of the Russian Federation
Human Ecology | Year: 2016

With the aim of studying the features of the vegetative components of cardiac activity in the period of functional stress of the body, that are interesting for study of adaptive changes in the human circulatory system, there has been studied the heart chronotropic response to the paired somato-vegetative cardiac reflex caused by a modified breakdown Aschner-Danini in first year military servicemen and students of the Syktyvkar State University in conditions of relative rest and after physical loading, samples Martin-Kushelevsky. With use of the method of electrocardiography in the second standard lead, there were recorded RR-intervals before and after functional tests. It has been found that in the servicemen with the heart heterogeneous chronotropic function which bodies adapted to new environments, vagal samples in the body state of relative rest caused a bigger heterogeneous chronotropic response of the heart than in the students adapted to external conditions. After the subjects underwent exercise loading, the heart response to induced coupled cardiac reflex was unidirectional and more pronounced than at rest. The results indicated increased influence of the vagus on the heart work in conditions of the body mobilization. Associated vagal test combined with the exercise loading is the method of choice in evaluation of the autonomic system regulating the circulation homeostasis in conditions of high requirements to the body.


Golubinskii A.N.,The Ministry of Internal Affairs of the Russian Federation
Telecommunications and Radio Engineering (English translation of Elektrosvyaz and Radiotekhnika) | Year: 2012

Applying a stochastic approach, mathematical models of a speech signal, built on the theory of modulation, were generalized. The possibility of transition from a stochastic mathematical model to quasidetermined and determined models in particular cases was discussed. © 2012 by Begell House, Inc..


Yurevna Kolosova O.,The Ministry of Internal Affairs of the Russian Federation
Life Science Journal | Year: 2014

This article discusses some general issues related to the definition of globalism as a special branch of science, its subject, status, terminology, the situation in the modern sciences. The concept "globalization" is included in a turn and is widely adopted in connection with discussion among scientists, politicians, journalists of crisis of 1997-1999 of the XX century, discussions about prospects of the world and the certain countries. For the first time the term was used in 1967 for designation bigger, than before depth of the international integration.


Golubinskii A.N.,The Ministry of Internal Affairs of the Russian Federation
Telecommunications and Radio Engineering (English translation of Elektrosvyaz and Radiotekhnika) | Year: 2012

A new method for calculated estimation of the speech signal base frequency, on the basis of the minimal correlation coefficient discrepancy, is developed. This method of estimation of the base frequency was compared with the amplitude, correlation and spectral methods and the wavelet method. © 2012 by Begell House, Inc.


Bel'kheeva R.K.,The Ministry of Internal Affairs of the Russian Federation
Journal of Applied Mechanics and Technical Physics | Year: 2012

A method of constructing the equation of state of a simple thermodynamically equilibrium mixture is proposed. The method is based on the hypothesis of additivity of the species volumes. The equilibrium state is determined by the conditions of equality of pressures, temperatures, and velocities of the species. The mixture is described by the model of interpenetrating and interacting continua, which takes into account the gas presence in pores. The equations of state of the mixture and all species, including the gaseous species, are presented in a unified manner (in the form of the Mie-Grüneisen equation). Presentation of functions in the form of Taylor series yields relations that allow the parameters of the equation of state of the mixture to be expressed via the corresponding parameters and mass fractions of individual species. Numerical calculations of shock wave loading and isentropic expansion are performed for solid and porous copper, tungsten, tungsten-copper mixture, and tungsten-nickel-copper mixture. It is demonstrated that the resultant equation of state of the mixture ensures a fairly accurate description of multispecies media with shock and expansion waves propagating in these media. © 2012 Pleiades Publishing, Ltd.


Sizonenko A.B.,The Ministry of Internal Affairs of the Russian Federation
Automatic Control and Computer Sciences | Year: 2013

Methods for vector and multiple logical computations are described. An algorithm is presented that allows for parallel computations of the values of the conjunctive terms of generalized polynomial forms using multiple sets of variables. Evaluations of the performance of the proposed algorithm are given. An example of multiple parallel computations of the terms of an arithmetic polynomial is analyzed. © 2013 Allerton Press, Inc.


Sizonenko A.B.,The Ministry of Internal Affairs of the Russian Federation
Automatic Control and Computer Sciences | Year: 2013

An algorithm for the simultaneous calculation of several conjunction terms of the Zhegalkin (Reed-Muller) polynomial with fixed polarity and an arithmetic polynomial on the same set of variables is proposed. The performance evaluation of the proposed algorithm is presented. An example of the simultaneous calculation of the arithmetic polynomial's terms is described to demonstrate an increase in the calculation performance. © 2013 Allerton Press, Inc.


News Article | August 15, 2015
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