The Maternity and Childrens Vall dHebron Hospital

Barcelona, Spain

The Maternity and Childrens Vall dHebron Hospital

Barcelona, Spain

Time filter

Source Type

Fadeeva T.,The Maternity and Childrens Vall dHebron Hospital | Eseverri Asin J.L.,The Maternity and Childrens Vall dHebron Hospital | Labrador Horrillo M.,The Maternity and Childrens Vall dHebron Hospital | Garriga Baraut T.,The Maternity and Childrens Vall dHebron Hospital | And 5 more authors.
Allergologia et Immunopathologia | Year: 2010

Introduction: Egg allergy is an adverse immune-system reaction of an IgE-mediated type, which can happen in children after egg intake and several times after their first egg intake. Objectives: Compare the results of the oral egg-challenge test in two groups of egg-sensitised children, with and without prior intake. Patients and methods: Retrospective study of two egg-sensitised groups (72 subjects).Group 1: 22 children without prior egg-intake.Group 2: 50 children with a clinical history of adverse reactions after egg intake.Skin prick tests, egg-white specific IgE (sIgE) and yolk specific IgE, were performed on all children. The oral egg-challenge tests were performed after a period of egg-avoidance diet and when egg-white specific IgE levels were lower than 1.5. KU/L. Results: 31.8% of the children in Group 1 did not tolerate egg-intake whereas 38% of the children in Group 2 did not tolerate egg-intake. Egg-avoidance periods lasted 19.5 and 18 months, respectively.Egg-white specific IgE levels went down in both groups after an egg-avoidance diet. No statistically significant differences were found between the groups and the positivity of oral egg-challenge test. Conclusions: No statistically significant differences were found in the behaviour of the two groups studied.Given the high risk of adverse reactions, it was recommended that any egg-introduction tests were to be performed in a hospital environment on the children who were sensitised to hen's egg (including children without prior egg intake). © 2009 SEICAP.


Egg allergy is an adverse immune-system reaction of an IgE-mediated type, which can happen in children after egg intake and several times after their first egg intake.Compare the results of the oral egg-challenge test in two groups of egg-sensitised children, with and without prior intake.Retrospective study of two egg-sensitised groups (72 subjects). Group 1: 22 children without prior egg-intake. Group 2: 50 children with a clinical history of adverse reactions after egg intake. Skin prick tests, egg-white specific IgE (sIgE) and yolk specific IgE, were performed on all children. The oral egg-challenge tests were performed after a period of egg-avoidance diet and when egg-white specific IgE levels were lower than 1.5K U/L.31.8% of the children in Group 1 did not tolerate egg-intake whereas 38% of the children in Group 2 did not tolerate egg-intake. Egg-avoidance periods lasted 19.5 and 18 months, respectively. Egg-white specific IgE levels went down in both groups after an egg-avoidance diet. No statistically significant differences were found between the groups and the positivity of oral egg-challenge test.No statistically significant differences were found in the behaviour of the two groups studied. Given the high risk of adverse reactions, it was recommended that any egg-introduction tests were to be performed in a hospital environment on the children who were sensitised to hens egg (including children without prior egg intake).

Loading The Maternity and Childrens Vall dHebron Hospital collaborators
Loading The Maternity and Childrens Vall dHebron Hospital collaborators