News Article | March 2, 2017
NEW YORK, NY--(Marketwired - March 02, 2017) - "Songwriters: The Next Generation," a program of The ASCAP Foundation and the John F. Kennedy Center for the Performing Arts, showcases the work of four young songwriters and composers in free concerts on the Kennedy Center's Millennium Stage on Thursday, March 9 and Friday, March 10. On March 9, Alabama-based singer/songwriter Wilder Adkins takes the stage to perform his original work. The bill also features the Jean John Trio performing original jazz compositions by Žan Tetičkovič a Slovenian born New York City based drummer, educator and multi-award winning composer. On March 10, Paperwhite, a Brooklyn-based dream-pop brother and sister duo, Ben and Katie Marshall, perform their works followed by jazz vocalist and composer, Laurin Talese and her band. Each evening's hour-long program, designed to spotlight the talent of young songwriters and composers, is hosted by celebrated singer/songwriter and arts entertainment producer Larry Groce. Groce is one of the founders of Mountain Stage, a live music program on NPR produced by West Virginia Public Radio. The concerts and Q & A take place from 6-7 pm each evening, and is webcasted live and archived for future viewing at http://www.kennedy-center.org/programs/millennium/ "Songwriters: The Next Generation" was conceived by pianist, educator, composer and ASCAP Foundation board member Dr. Billy Taylor, who also served as Artistic Director for Jazz at the John F. Kennedy Center for the Performing Arts from 1994 until he passed away in 2010. Throughout his life, Dr. Taylor stressed the importance of showcasing contemporary composers and songwriters who are also performers. "Songwriters: The Next Generation," presented by The ASCAP Foundation and made possible by the Bart Howard Estate, is part of the Kennedy Center's free daily performance series. ASCAP member Bart Howard (1915 - 2004) was the writer of the great standard, "Fly Me to the Moon." Wilder Adkins is a singer-songwriter from Birmingham, Alabama and has performed at NYC's Lincoln Center and the Sundance Film Festival. He is also a winner of the prestigious New Song Music Songwriting Competition. Adkins recently released a new album Hope & Sorrow and has toured the UK. His songwriting gleans as much from the earthy poetry of Wendell Berry and Marry Oliver as it does from the works of folk luminaries Richard Thompson and Bruce Cockburn, and he possesses startling guitar skills and a voice that mesmerizes as he sings of faith, doubt, and as the title of his new album indicates, hope and sorrow. Žan Tetičkovič is a New York City based drummer, educator and award-winning composer originally from Ptuj, Slovenia. He graduated from The New School for Jazz and Contemporary Music in 2015 with academic honors for performance and composition. He is also a recipient of the 2012, 2014 and 2017 Herb Alpert Young Jazz Composers Award and has performed at renowned festivals and venues for notable artists and acts around the world. Tetičkovič mainly draws inspirations for his compositions from global issues, with his world music project Balchemy, philanthropic project Oasis (2014), and The Port of Life, a story that discusses immigration and acculturation. Tetičkovič is currently composing his first "climate change" classical symphony and has been commissioned by the National Theater of Slovenia to compose an opera about islamophobia, Alamut, which is set to premiere in 2020. He also plans to release his second record, with a trio featuring pianist Aaron Diehl and bassist Russell Hall in 2017. Paperwhite, a dream-pop duo from Brooklyn, NY, consists of brother and sister Katie and Ben Marshall. Katie's sophisticated melodies are uniquely sung over synthesized textures as Ben, a drummer, producer, and co-writer, creates the musical instrumentation with synths and hypnotic pounding drums. They released their debut EP Magic in 2014, receiving the Hype Machine title of "Most Blogged Artists" twice in a row. In November 2015, they released "Get Away", the first single off their sophomore EP Escape, along with a breathtaking music video shot in Iceland. Escape has since caught the attention of top platforms in the music industry, with premiers from Billboard, Buzzfeed and Noisey. Paperwhite is also on Spotify and many other curated playlists. Their third EP is expected to be released this spring. Laurin Talese is a jazz singer-songwriter who has been performing since the young age of ten. Her vocals fuse jazz, r&b and soul elements, creating a sound that is both classic and fresh. Talese has worked with numerous recording artists including Ed Sheeran, Christian McBride, Robert Glasper and Vivian Green. Her greatest affinity is jazz, however, Talese is versatile within many musical genres. She recently partnered with Grammy-award winning drummer and producer, Ulysses Owens Jr., and internationally acclaimed music director and producer, Adam Blackstone, to create her highly anticipated debut album Gorgeous Chaos Released in 2016, it charted at #14 on the Billboard's Jazz Chart. Laurin currently resides in Philadelphia. Founded in 1975, the ASCAP Foundation is a public charity dedicated to supporting American Music creators and encouraging their development through music education and talent development programs. Included in these are songwriting workshops, grants, scholarships, awards, recognition, and community outreach programs for songwriters, composers and lyricists. The ASCAP Foundation is supported by contributions by ASCAP members and from music lovers throughout the United States. www.ascapfoundation.org The Kennedy Center is the only U.S. institution that presents a free performance 365 days a year. Created in 1997 and underwritten by James A. Johnson and Maxine Isaacs, the Millennium Stage features a broad spectrum of performing arts each day at 6 p.m. Brought to the public by Target Stores and The J. Willard and Alice S. Marriott Foundation, the Millennium Stage helps fulfill the Center's mission of making the performing arts accessible to everyone. In the past 19 years, more than 3 million visitors have enjoyed more than 7,000 groups. Through intentionally identifying artistic partners regionally, nationally, and internationally, performances reflect the breadth and depth of culture in society, exploring styles including jazz, ballet, storytelling, popular music, Hip Hop, contemporary dance, opera, choral music, tap dance, theater, chamber music, symphonic music, puppetry, stand-up comedy, and cabaret. Of the many performers that have appeared on the Millennium Stage, approximately 25,000 have been Washington-area artists and more than 6,000 have been international performing artists representing more than 50 countries. The Millennium Stage has also hosted artists representing all 50 states, and has presented more than 15,000 artists in their Kennedy Center debuts. Since 1999, each night's performance has been broadcast live over the internet, and more than 4,430 of these performances have been digitally archived on the Kennedy Center's website, kennedy-center.org.
Sehested L.T.,Roskilde Hospital |
Moller R.S.,Danish Epilepsy Center |
Moller R.S.,Copenhagen University |
Bache I.,Copenhagen University |
And 5 more authors.
American Journal of Medical Genetics, Part A | Year: 2010
We describe a chromosome rearrangement, ins(7;13)(q32q34;q32), which segregates in a three generation family, giving rise to three individuals with an unbalanced rearrangement. Two of the individuals, a sister and a brother, were investigated further in this study. They had minor facial dysmorphism and neuropsychiatric disorders including mental retardation, language delay and epilepsy. The sister had primary amenorrhea. Array CGH revealed a 12.2 Mb deletion at 7q34-q36.2 including more than 60 genes where CNTNAP2 and NOBOX are of special interest. Comparison of the clinical and cytogenetic findings of our patients with previously reported patients, supports that haploinsuffiency of CNTNAP2 can result in language delay and/or autism spectrum disorder. Furthermore, we report on the second women with a deletion involving NOBOX who is affected by primary amenorrhea. © 2010 Wiley-Liss, Inc..
News Article | November 10, 2016
NEW YORK, Nov. 10, 2016 (GLOBE NEWSWIRE) -- The Madison Square Garden Company announced today the 37th consecutive show by legendary musician and MSG franchise Billy Joel. The January 11th show is part of his residency at The World’s Most Famous Arena which began in January 2014 with Joel playing one show per month at The Garden as part of the Time Warner Cable Concert Series, for three consecutive years. The January show will be Joel’s 83rd all-time performance at The Garden. Citi cardmembers will have exclusive access to presale tickets for the January 11 show from Monday, November 14 at 10:00AM (EST) through Thursday, November 17 at 10:00PM (EST) via www.citiprivatepass.com. Tickets for the January 11 show will be available for purchase by the general public beginning at 10:00AM (EST) on Friday, November 18 via ticketmaster.com and by calling Ticketmaster at 866-858-0008. Tickets will also be available at the Madison Square Garden box office on Saturday, November 19. Prices range from $65.50 to $129.50. The concerts are being promoted by The Madison Square Garden Company in association with AEG Live and Q104.3 as a media partner. In December 2013, Billy Joel became Madison Square Garden’s first-ever music franchise, joining the ranks of the storied venue’s other original franchises – the New York Knicks, Rangers and Liberty. Since January 2014, Joel has played one show per month at The Garden as part of the Time Warner Cable Concert Series. This unprecedented and wildly successful residency has led to 36 sold-out shows through December 2016. Having sold 150 million records over the past quarter century, Billy Joel ranks as one of most popular recording artists and respected entertainers in history. The singer/songwriter/composer is the sixth best-selling recording artist of all time, the third best-selling solo artist and is one of the highest grossing touring artists in the world. Joel is also one of the biggest live performing artists in the world and his concerts continue to break records in both arenas and baseball stadiums. In November 2014, Billy Joel received both The Library of Congress Gershwin Prize for Popular Song which honors living musical artists’ lifetime achievement in promoting the genre of song as a vehicle of cultural understanding; entertaining and informing audiences; and inspiring new generations, and the once-in-a-century ASCAP Centennial Award, which is presented to American music icons in recognition of their incomparable accomplishments in their respective music genres and beyond. In December 2013, Joel received The Kennedy Center Honors, one of the United States' top cultural awards. He is also the recipient of six GRAMMY® Awards, including the prestigious Grammy Legend Award. Joel has been inducted into the Songwriter’s Hall of Fame and the Rock and Roll Hall of Fame and has received numerous industry awards including a TONY AWARD for "Movin' Out," a Broadway musical based on Joel’s music. For his accomplishments as a musician and as a humanitarian, Joel was honored as the 2002 MusiCares Person Of The Year by the MusiCares Foundation and the National Academy of Recording Arts & Sciences. Joel has also performed alongside other music greats at two of Madison Square Garden’s most extraordinary benefit concerts – “12-12-12, The Concert For Sandy Relief,” which raised awareness and money for those affected by Hurricane Sandy and “The Concert for New York City,” which was held to help aid 9/11 victims and heroes. Billy Joel received a star on the Hollywood Walk of Fame in Los Angeles, adding another milestone to his brilliant career. MSG now offers a rich visual history of Billy Joel and his many Garden performances through a scrollable timeline featuring archival images, video insights from Billy, sharable images and lyrics, plus direct links for ticketing. Visit billyjoelmsg.com for more information. Join the conversation with #BillyJoelMSG. About The Madison Square Garden Company The Madison Square Garden Company (MSG) is a world leader in live sports and entertainment with a portfolio of legendary sports teams, exclusive entertainment productions and celebrated venues. MSG Sports owns and operates some of the most widely recognized sports franchises: the New York Knicks (NBA), the New York Rangers (NHL) and the New York Liberty (WNBA), along with two development league teams -- the Westchester Knicks (NBADL) and the Hartford Wolf Pack (AHL). MSG Sports also presents a broad array of world-class sporting events, including: professional boxing, college basketball, tennis, bull riding and e-gaming events. MSG Entertainment features exclusive, original productions that include the Christmas Spectacular Starring The Radio City Rockettes and New York Spectacular Starring The Radio City Rockettes. MSG Entertainment also presents or hosts a wide variety of live entertainment offerings, including concerts, family shows and special events, in the Company’s diverse collection of iconic venues. These venues are: New York’s Madison Square Garden, The Theater at Madison Square Garden, Radio City Music Hall and Beacon Theatre; the Forum in Inglewood, California; The Chicago Theatre; and the Wang Theatre in Boston, MA. More information is available at www.themadisonsquaregardencompany.com.
McLaughlin J.R.,The Kennedy Center |
Lee K.R.,Gundersen Lutheran Medical Center
Journal of Arthroplasty | Year: 2016
Background: Previously, we reported the mean 16-year results of primary uncemented total hip arthroplasty using a tapered femoral component in patients <50 years. The purpose of this study was to update our previous report using the Taperloc femoral component in young patients who had been followed for a minimum of 20 years postoperatively. Methods: Between 1983 and 1990, 108 consecutive uncemented total hip arthroplasties were performed in 91 patients of age <50 years, with use of the Taperloc femoral component. Every patient was followed for a minimum of 20 years after surgery or until death. At a mean of 25 (range, 20-29 years) postoperatively, 76 patients (91 hips) were living. The Harris Hip Score, radiographic results, complications, and Kaplan-Meier survivorship were evaluated. Results: In the entire cohort of 108 hips, 9 femoral components (8%) have been revised, none for aseptic loosening. Five well-fixed stems were removed during acetabular revision, 3 stems were revised for infection, and 1 stem was exchanged because of a peroneal nerve palsy. Distal femoral osteolysis was identified around 1 hip. With failure defined as stem removal for any reason, implant survival was 90% (CI = 82-95) at 29 years. With failure defined as stem removal for aseptic loosening, implant survival was 100% at 29 years. Conclusion: Primary total hip arthroplasty with the Taperloc femoral component in young patients was associated with a high rate of survival at 29 years. © 2015 Elsevier Inc.
Gronskov K.,Center for Applied Human Molecular Genetics |
Poole R.L.,University of Southampton |
Poole R.L.,Salisbury Hospital NHS Foundation Trust |
Hahnemann J.M.D.,Center for Applied Human Molecular Genetics |
And 13 more authors.
Journal of Medical Genetics | Year: 2011
Silver-Russell syndrome (SRS) is characterised by prenatal and postnatal growth retardation, dysmorphic facial features, and body asymmetry. In 35-60% of SRS cases the paternally methylated imprinting control region (ICR) upstream of the H19 gene (H19-ICR) is hypomethylated, leading to downregulation of IGF2 and bi-allelic expression of H19. H19 and IGF2 are reciprocally imprinted genes on chromosome 11p15. The expression is regulated by the imprinted methylation of the ICR, which modulates the transcription of H19 and IGF2 facilitated by enhancers downstream of H19. A promoter element of IGF2, IGF2P0, is differentially methylated equivalently to the H19-ICR, though in a small number of SRS cases this association is disrupted-that is, hypomethylation affects either H19-ICR or IGF2P0. Three pedigrees associated with hypomethylation of IGF2P0 in the probands are presented here, two with paternally derived deletions, and one with a balanced translocation of inferred paternal origin. They all have a breakpoint within the H19/IGF2 enhancer region. One proband has severe growth retardation, the others have SRS. This is the first report of paternally derived structural chromosomal mutations in 11p15 causing SRS. These cases define a novel aetiology of the growth retardation in SRS, namely, dissociation of IGF2 from its enhancers. © 2011 by the BMJ Publishing Group Ltd.
Schrade C.,The Kennedy Center |
Tronsky L.,Albertus Magnus College |
Kaiser D.H.,Albertus Magnus College
Arts in Psychotherapy | Year: 2011
This study investigated mandala making as an effective physiological stress reducer for individuals with intellectual disability. Stress levels were measured using systolic and diastolic blood pressure and pulse. Participants (N=15) engaged in three activities, serving as their own controls: mandala making, free drawing and a neutral control condition. Findings revealed no significant differences in changes in stress measures across the three conditions, however, t-tests of blood pressure change in the mandala making condition indicated a statistically significant reduction in both diastolic and systolic pressure between the first and third reading; similar differences were not found in the other two conditions. These findings suggest that mandala making is an effective stress reducer for those with intellectual disability, however, evidence does not show it is more effective than the control conditions. Suggestions for future research are discussed. © 2011 Elsevier Inc.
Munch I.C.,Glostrup Hospital |
Munch I.C.,The Research Center for Prevention and Health |
Munch I.C.,Copenhagen University |
Ek J.,The Kennedy Center |
And 10 more authors.
Investigative Ophthalmology and Visual Science | Year: 2010
Purpose. To study associations of small, hard macular drusen and peripheral drusen with genotypes associated with agerelated macular degeneration (AMD). Methods. Digital grayscale fundus photographs recorded in red-free illumination were graded for the presence of drusen in 1107 subjects aged 30 to 66 years. Participants were genotyped for AMD-related polymorphisms in complement factor H (CFH), in LOC387715, and in complement factor B (CFB). Results. The prevalence of 20 or more small, hard macular drusen per eye was 14%, with no association to the investigated polymorphisms. Peripheral drusen were associated with CFHY402H (odds ratio [OR], 4.3; 95% confidence interval [95% CI], 1.4 -13, for CC versus TT genotypes) as was macular drusen >63 μm (OR, 1.9; 95% CI, 1.1-3.1, for CC versus TT genotypes). Macular drusen >63 μm were associated with the presence of 20 or more small, hard macular drusen (OR, 1.7; 95% CI, 1.1-2.6) and with peripheral drusen (OR, 2.5; 95% CI,1.2-5.4) Conclusions. In this study, the presence of 20 or more small, hard macular drusen per eye was not associated with known AMD-related polymorphisms, whereas the study confirmed an association of peripheral drusen with CFHY402H. © Association for Research in Vision and Ophthalmology.
Skjorringe T.,The Kennedy Center |
Tumer Z.,The Kennedy Center |
Moller L.B.,The Kennedy Center
PLoS ONE | Year: 2011
Menkes disease (MD) is caused by mutations in the ATP7A gene. We describe 33 novel splice site mutations detected in patients with MD or the milder phenotypic form, Occipital Horn Syndrome. We review these 33 mutations together with 28 previously published splice site mutations. We investigate 12 mutations for their effect on the mRNA transcript in vivo. Transcriptional data from another 16 mutations were collected from the literature. The theoretical consequences of splice site mutations, predicted with the bioinformatics tool Human Splice Finder, were investigated and evaluated in relation to in vivo results. Ninety-six percent of the mutations identified in 45 patients with classical MD were predicted to have a significant effect on splicing, which concurs with the absence of any detectable wild-type transcript in all 19 patients investigated in vivo. Sixty-seven percent of the mutations identified in 12 patients with milder phenotypes were predicted to have no significant effect on splicing, which concurs with the presence of wild-type transcript in 7 out of 9 patients investigated in vivo. Both the in silico predictions and the in vivo results support the hypothesis previously suggested by us and others, that the presence of some wild-type transcript is correlated to a milder phenotype. © 2011 Skjørringe et al.
PubMed | The Kennedy Center
Type: Journal Article | Journal: Human mutation | Year: 2010
Bardet-Biedl syndrome (BBS) is an autosomal recessive disease characterized by retinal dystrophy, polydactyly, obesity, learning disabilities, renal involvement, and male hypogenitalism. BBS is genetically heterogeneous with mutations of 14 genes, accounting for approximately 70% of cases. Triallelic inheritance has been suggested in about 5% of cases. Forty-nine unrelated BBS patients were screened for mutations by DHPLC analysis in BBS1, BBS2, BBS4, BBS6/MKKS, BBS10, and BBS12. The selected genes either account for more than 5% of the mutational load or are commonly reported in triallelic inheritance. Eight patients with only one or no BBS mutation were further investigated by single nucleotide polymorphism (SNP) analysis. In total, mutations were detected in 44 patients. Twenty percent had two mutations in BBS1, 18% in BBS2, 4% in BBS9, 43% in BBS10, and 2% in BBS12. Five patients were heterozygous for a sequence variation in BBS6/MKKS. We found eight patients with three sequence variations in two genes, which could be explained by triallelic inheritance, by the prevalence of heterozygous carriers or the third sequence variations representing rare polymorphisms. All changes found in a second BBS gene were amino acid substitutions. Genotype-phenotype correlations suggest a milder phenotype for BBS1 compared to BBS2 and BBS10, which we ascribe to the hypomorphic p.Met390Arg-mutation.
News Article | November 9, 2015
Dustin Yellin, a 40-year-old Brooklyn artist who has posed naked for Vanity Fair, dated Michelle Williams, and billed as the art world's next "it boy," is a fun guy to interview. Over the phone, he asked me if I thought God had fuzzy bunny ears, and thought that after you died, you went to a level-select screen, like in some giant cosmic video game. Talking to him is like being dropped into a kaleidoscope where references to art, pop culture, and the metaphysical all sort of swirl in explosions together. In other words, Yellin, the person, is a lot like the six new figures he has put on display outside of the six-building Columbia Square Compound in Hollywood, which was for decades the headquarters of CBS's West Coast operations. He calls them Psychogeographies, and although they resemble three-dimensional figures from afar, their volume is actually an optical illusion, created by sandwiching cuttings from magazines, photographs, and books between up to 28 distinct layers of glass. Yellin thinks of them as colorful explosions of humanity, like a Body Worlds sculpture, except instead of bone, blood, and guts, he uses a person's thoughts, emotions, fears, and pop-culture fascinations. Yellin has made about 80 Psychogeographies to date. Helped by a team of assistants, each one starts with some almost stream-of-conscious spitballing from Yellin. "I'll create some crazy multi-dimensional narrative that will live within the vessel," he says. "I might say, this one's going to have two heads, and both heads will telepathically be communicating with each other by this tendril of thought, and I want there to be a seascape inside the chest cavity, made up of Roman and pre-Columbian artifacts, and small children falling into the sea." To make these ideas a reality, Yellin has an extensive cutting room, with a "taxonomy of drawers" which file away pre-clipped images and photos; there are drawers for humans, mushrooms, trees, plants, African artifacts, icebergs, and so on. After finding all the proper images, Yellin and his team spend months arranging them on slides of glass, then fit them together until they create the illusion of a 3-D figure, trapped within a tank. Although Yellin's design process sounds scattershot, many of his Psychogeographies have focused themes. A recent installation Yellin did for The Kennedy Center contained 12 figures, originally exhibited by the New York City Ballet, all arranged in 12 poses. And for the Columbia Square Compound, all six Psychogeographies on display were all created with Tinseltown ephemera, including cutouts of the Lone Ranger, Orson Welles, and Bob Dylan, among other. "I snuck into these explosions of consciousness all these different attributes that correlate to the landscape of Hollywood, a city that's going to eventually fall into the sea, and which is the strange environment which creates all these movies in our lives," he says. Yellin has no intention to stop making Psychogeographies any time soon, telling me he eventually hopes to top out at 120. Why 120? Here, the sly businessman behind the eccentric artist slips into the conversation. "It's arbitrary," he admits. "But I'm hedging my bets that if I make 120, I'll get at least 48 back from installations and exhibitions at the end of the day, which will be enough to take this show on the road."