Li M.-Z.,The First Peoples Hospital of Jingzhou City |
Hu X.-M.,The First Peoples Hospital of Jingzhou City
World Chinese Journal of Digestology | Year: 2014
Aim: To investigate the treatment and survival of gastric cancer patients with metachronous liver metastases. Methods: Clinical data for 92 gastric cancer patients pathologically diagnosed with metachronous liver metastases treated from January 2004 to December 2009 were included. The patients received treatments including chemotherapy (n = 44), chemotherapy + hepatic artery chemoembolization (TACE) (n = 28), and chemotherapy + liver cancer resection (n = 20). The patients were followed for 6 mo to 70 mo, and the 5-year survival rate was calculated. Prognostic factors were assessed using univariate and Cox regression analysis. Results: The total effective rate was 50.00% and the 1-, 3- and 5-year survival rates were 72.73%, 22.73% and 2.27% in the patients receiving chemotherapy alone; the corresponding percentages were 57.14%, 71.43%, 28.57% and 10.71% in the chemotherapy + TACE group, and 60.00%, 75.00%, 60.00% and 40.00% in the chemotherapy + liver cancer resection group. Although the total effective rate and 1-year survival rate showed no significant difference among the three group (P > 0.05), the differences in the 3- and 5-year survival rates were statistically significant (P < 0.05). Univariate analysis showed that the diameter of primary tumor, differentiation, hepatic metastasis, liver cancer type, the number of cancer metastases, and treatment efficacy were associated with the prognosis in gastric cancer patients with metachronous liver metastases (all P < 0.05). Cox regression analysis showed that the diameter of primary tumor, the number of liver metastases and liver cancer type were independent risk factors. Conclusion: Chemotherapy + liver cancer resection can effectively improve survival in gastric cancer patients with metachronous liver metastases. When selecting appropriate treatment, the type of liver cancer, tumor size and the number of liver metastases should be taken into account. © 2014 Baishideng Publishing Group Inc. All rights reserved.
Luo W.,The First Peoples Hospital of Jingzhou City |
Li M.-X.,The First Peoples Hospital of Jingzhou City |
Zheng W.-H.,The First Peoples Hospital of Jingzhou City |
Ding M.-Y.,Huazhong University of Science and Technology
Yiyong Shengwu Lixue/Journal of Medical Biomechanics | Year: 2014
Objective: In order to meet the needs of more precise surgical navigation during interventional procedures and minimally invasive surgery, Aurora electromagnetic tracking technology-assisted surgical navigation with free combination of various surgical instruments was tested, trying to further solve problems encountered in surgery. Methods: Aurora electromagnetic tracking system was used to match the medical surgical environment with metal-containing material. The built-in control software in this electromagnetic tracking system, which was equipped with the software development kit, was used to write a set of VC programming language suitable for real-time display of clinical surgical navigation system, and relative performance tests and comparative experiments were conducted for different medical surgical navigation application in the hospital to measure the precision degree of the tracking system, as well as the statistics of various surgical instruments corresponding to the application in different surgeries. Results: 160 patients in interventional surgery with coronary angiography were randomly selected, 80 patients treated by digital subtraction angiography (DSA) with electromagnetic tracking systems as the experimental group, and 80 patients by DSA only as the control group. It was found out that with obviously less operating time, the amount of contrast agent was significantly reduced in the experimental group, and the degree of controllability for interventional surgical procedure was increased from 95% success rate to 99%. Conclusions: The comparative experiments proved that Aurora electromagnetic tracking technology could significantly improve the accuracy in surgery, with the mean value of navigation less than 2 mm. In terms of interventional procedures and minimally invasive surgery, this electromagnetic tracking technology can greatly relieve patients' suffering and reduce medical risks to make medical care safer, and enhance the surgical technology level in hospital.