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Zou H.,The First Peoples Hospital
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery | Year: 2012

To explore the clinical manifestations, diagnosis and treatment of primary thyroid B cells lymphoma. Eight cases of primary thyroid B cells lymphoma were retrospectively analysed, which were combinely diagnosed and treated. Follow up was being for two to seven years. Three cases were loss of visit, one case died, and four cases survived. Two-year survival rate was 85.1%, and five-year survival rate was 76.3%. A combination of various diagnostic and therapeutic methods of primary thyroid B cells lym-phoma can improve the diagnosis rate, reduce the misdiagnosis rate and improve the curative effect. Source


Wu S.,The First Peoples Hospital
Chinese Journal of Rehabilitation Medicine | Year: 2013

Objective: To study the effects of manipulation treatment on visual P300 potential of patients in cognitive function assessment after stroke. Method: Forty-eight patients were randomly divided into two groups, special manipulation treatment group (25 cases) and control group (23 cases). Patients in manipulation group were regularly given a passive quantitative movement on affected joints 1h/time, 2times/d, for lmonth, while patients in control group were irregularly given a passive movement or ordered to perform an autonomic movement. The visual P300 potential and mini-mental state examination (MMSE) assessment were administered pre-treatment and post-treatment (after one month) respectively. Result: (1) The latency of visual P300 was severely shortened after the manipulation treatment, and the amplitude of visual P300 wave was heightened significantly. (2) MMSE score increased after manipulation treatment, but the difference was not significant between 2 groups (P ≤ 0.05). Conclusion: Visual P300 indexes might be useful in measuring cognitive function changes after stroke and the special manipulation treatment could also improve the patient's cognitive function. Source


Zeng Y.,The First Peoples Hospital
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery | Year: 2011

To compare the therapeutic effect between endoscopic thyroidectomy and open thyroidectomy. One hundred and nine patients were randomly divided into two groups. The first group with 52 patients were carried out endoscopic thyroidectomy; and the second group with 57 patients was carried out open thyroidectomy. Clinical features including operation time, operative blood loss, hospitalization and complications were compared between the two groups. The average operative time was (105.1 +/- 30.2) min in endoscopic group and (145.3 +/- 27.4) min in open group (P<0.01); the mean operative blood loss was (7.5 +/- 4.2) ml in endoscopic group and (48.6 +/- 18.6) ml in open group (P<0.01); the average hospitalization after operation was (4.1 +/- 1.4) days and (8.0 +/- 1.9) days (P<0.01), the complication rate was 5.8% in endoscopic group and 8.8% in open group (P<0.01). Compared to the traditional open surgery, endoscopic thyroidectomy is safe and effective,with advantages in terms of the aesthetic property,the amount of bleeding and the postoperative complications. Source


Zhou R.-Z.,The First Peoples Hospital
International Eye Science | Year: 2013

AIM: To explore the effect of glaucoma drugs joint surgical treatment on patients with tear of MUC5AC and ocular surface. METHODS: Totally 26 cases (29 eyes) underwent glaucoma and cataract surgery who with history of glaucoma drugs admitted to our hospital in March 2010 to September 2011 were included. The content of tear MUC5AC and the ocular surface function scores of patients and healthy people at different time point were measured and analyzed. The relativity between types and taking time of medication, and ocular surface function scores before and after surgery was analyzed. The change of ocular surface function score, and the content of tear MUC5AC before and after surgery was compared. RESULTS: Content of tear MUC5AC of glaucoma patients at each period was significantly lower than that of healthy people. There was statistically significance at preoperative 1 day, postoperative 1 month, 3 months (P=0.0168, P=0.0001, P=0.0150), and there was no statistically significance postoperative 6 months (P=0.2230). The content of tear MUC5AC of glaucoma patients decreased significantly post-operation, then gradually increased. Comparing the content of tear MUC5AC 1 month post-operation with 1 day pre-operation, 3 months and 6 months post-operation, there was statistically significance (P=0.0365, P=0.0329, P=0.0004). There was a positive correlation between preoperative ocular surface function score and the taking time and types of medication (P=0.0427, P=0.0327), and there was no correlation 6 months post-operation (P=0.1788, P=0.9916). The ocular surface function score of glaucoma patients was significantly higher, then gradually reduced, there was statistically significance between 1 month post-operation and 1 day pre-operation, 3 months and 6 months post-operation (P=0.0012, P=0.0001, P=0.0000). Ocular surface function score was significantly lower 6 months post-operation, compared with the preoperative 1 day, there was statistically significance (P=0.0049). CONCLUSION: Glaucoma medications combined with glaucoma and cataract surgery impaired tear MUC5AC and ocular surface, such kind of damage is more obvious with the increase of taking time and types of the drug and gradually improves with the post-operative time extending. Copyright 2013 by the IJO Press. Source


Fan C.X.,The First Peoples Hospital
Zhonghua zhong liu za zhi [Chinese journal of oncology] | Year: 2010

To explore the enhancing effect of compound Kusheg injection in chemotherapy for patients with stage III and IV non-small cell lung cancer (NSCLC). A total of 286 patients with advanced NSCLC were enrolled in this study. The patients were treated with either compound Kusheng injection in combination with NP (NVB + CBP) chemotherapy (vinorelbine and carboplatin, n = 144), or with NP (NVB + CBP) chemotherapy alone (n = 142). The chemotherapy was performed for 4 cycles of 3 weeks, and the therapeutic efficacy was evaluated every 2 weeks. The following indicators were observed: levels of Hb, WBC, PLT and T cell subpopulations in blood, serum IgG level, short-term efficacy, adverse effects and quality of life. The gastrointestinal reactions and the myelosuppression in the combination chemotherapy group were alleviated as compared with the chemotherapy alone group, showing a significant difference (P < 0.05). CD(8)(+) cells were markedly declined in the combination chemotherapy group, and the CD(4)(+)/CD(8)(+) ratio showed an elevation trend in the chemotherapy alone group. The KPS scores and serum IgM and IgG levels were higher in the combination chemotherapy group than those in the chemotherapy alone group (P < 0.01 and P < 0.05). The serum lgA levels were not significantly different in the two groups. The compound Kusheng injection plus NP chemotherapy regimen shows better therapeutic effect, reduces adverse effects of chemotherapy and improves the quality of life in patients with stage III and IV NSCLC. Source

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