The First Affiliated Hospital of Xian Medical College University

Fengcheng, China

The First Affiliated Hospital of Xian Medical College University

Fengcheng, China
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Li J.-H.,PLA Fourth Military Medical University | Li J.-H.,Academy of Military Medical Science | Jiang D.-P.,Academy of Military Medical Science | Wang Y.-F.,U.S. Center for Disease Control and Prevention | And 7 more authors.
Environmental Toxicology and Pharmacology | Year: 2017

Public concern is growing about the exposure to electromagnetic fields (EMF) and its effect on male reproductive health. Detrimental effect of EMF exposure on sex hormones, reproductive performance and sex-ratio was reported. The present study was designed to clarify whether paternal exposure to electromagnetic pulse (EMP) affects offspring sex ratio in mice. 50 male BALB/c mice aged 5–6 weeks were exposed to EMP daily for 2 weeks before mated with non-exposed females at 0d, 7d, 14d, 21d and 28d after exposure. Sex hormones including total testosterone, LH, FSH, and GnRH were detected using radioimmunoassay. The sex ratio was examined by PCR and agarose gel electrophoresis. The results of D0, D21 and D28 showed significant increases compared with sham-exposed groups. The serum testosterone increased significantly in D0, D14, D21, and D28 compared with sham-exposed groups (p < 0.05). Overall, this study suggested that EMP exposure may lead to the disturbance of reproductive hormone levels and affect the offspring sex ratio. © 2017

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