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Patent
The-Edge | Date: 2016-11-17

According to some embodiments, a skin treatment assembly comprises a handpiece comprising a distal end, the handpiece comprising a recess or cavity configured to receive a cartridge or other fluid container, a tip configured to be positioned along the distal end of the handpiece, the tip being configured to contact a skin surface of a subject during use, and at least one rollerball configured to extend to or near the tip, wherein the rollerball is configured to be in fluid communication with an interior of a cartridge or other fluid container secured to the handpiece, wherein the at least one rollerball is configured to contact the skin surface of the subject during use and to facilitate the delivery of fluids to said skin surface as the rollerball is moved relative to said skin surface.


Patent
The-Edge and Ludwig Institute for Cancer Research | Date: 2016-12-27

The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.


Patent
The-Edge | Date: 2015-07-06

A convertible pallet alternately displays and ships/transports associated product received thereon is disclosed herein. The pallet includes a substantially planar support member for receiving the associated product thereon. At least first and second wheels are mounted to the pallet. A convertible support surface is movably mounted to the pallet, the convertible support surface having (i) a first position where the convertible support surface receives loads imposed on the upper surface and transfers the loads directly to an associated surface, and (ii) a second position where the wheels extend outwardly from the lower surface for engagement with the associated surface so that loads imposed on the upper surface are transferred to the associated surface through the wheels and for converting the pallet into a movable cart.


An energy saving alternate current (AC) series voltage regulator comprises an AC high frequency (HF) series voltage buck power regulator, a bypass contactor (K1), a bidirectional AC semiconductor device (S1) connected in parallel with the bypass contactor and a control circuitry. Under the condition of an input AC mains voltage (Vin) drops below a specified and set optimum energy savings voltage or a lower selected voltage point, the control circuitry transitions both the slow bypass contactor and the fast bidirectional AC semiconductor device, then the AC high frequency (HF) series voltage buck power regulator are switched out to save the AC high frequency (HF) series voltage buck power regulator internal power electronics usage. Under this condition, the lower input AC mains voltage is directly delivered to an electrical load by the contactor bypass system, hence achieving more energy savings.


Patent
The-Edge and Ludwig Institute for Cancer Research | Date: 2017-06-07

The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.


Patent
The-Edge | Date: 2016-11-04

A system and method for removing and replacing fire-tubes. The system can include a powered system, a fire-tube puller coupled to said powered system. The fire-tube puller has a puller back which is coupled to a plug rest. A plug rest is approximately perpendicular to the puller back, and the fire-tube will rest upon the plug rest when the fire-tube is being removed or installed. The system can also include a stack adjuster which is coupled to the plug rest. The stack adjuster can couple to a stack so as to reposition the stack.


An energy saving alternate current (AC) series voltage regulator comprises an AC high frequency (HF) series voltage buck power regulator, a bypass contactor (K1), a bidirectional AC semiconductor device (S1) connected in parallel with the bypass contactor and a control circuitry. Under the condition of an input AC mains voltage (Vin) drops below a specified and set optimum energy savings voltage or a lower selected voltage point, the control circuitry transitions both the slow bypass contactor and the fast bidirectional AC semiconductor device, then the AC high frequency (HF) series voltage buck power regulator are switched out to save the AC high frequency (HF) series voltage buck power regulator internal power electronics usage. Under this condition, the lower input AC mains voltage is directly delivered to an electrical load by the contactor bypass system, hence achieving more energy savings.


Patent
The-Edge | Date: 2017-01-13

A system for detecting presence of an external obstacle combining contact and non-contact sensing in a common safety edge of a motorized closure includes a sensing edge with an elongate sheath forming a cavity in which two electrically conductive elements are physically and electrically separated. A control circuit includes an oscillator electrically connected to the conductive elements and that drives each at a drive frequency to establish an electric field. A controller is electrically connected to the first and second conductive elements and determines whether (i) the first and second conductive elements are in electrical contact with one another or (ii) a change to the drive frequency exceeds a threshold value. In response to a finding of either condition (i) or (ii), the controller outputs a signal to initiate or disrupt motion of the motorized closure. Two inductors connected to the conductive elements isolate the oscillator from the controller.


Patent
The-Edge | Date: 2017-04-05

A flexible pipe fitting for joining a first length of pipe to a second length of pipe at an arbitrary angle is provided. The apparatus includes a primary fitting having a substantially circular opening at a first end thereof for receiving an end of a first length of pipe, and an enlarged opening at a second end thereof for receiving a first flexible coupling member. The first flexible coupling member includes an outer wall having an outer surface engaging an inner surface of the enlarged opening, and an inner wall having a lower end connected to a lower end of the outer wall. The inner wall further includes a substantially circular opening therein for receiving a second, rigid member. The inner surface of the second, rigid member is configured to receive an end of the second length of pipe. The enlarged opening in the primary fitting is preferably fish-mouth shaped, or alternatively, cone shaped. Adhesive, such as PVC cement may be used to bond the various fittings, and lengths of pipe together to form a sealed joint.


According to some embodiments, a skin treatment assembly comprises a tip comprising a proximal end and a distal end, a container configured to secure to the tip along the proximal end of the tip, wherein the container is configured to contain a liquid, and a porous member configured to extend at least partially within an interior of the container such that it contact a liquid contained within the container, wherein the porous member is configured to extend at least partially within an interior of the tip and is configured to facilitate the transfer of liquid from the container to the distal end of the tip.

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