London, United Kingdom
London, United Kingdom

Time filter

Source Type

PubMed | The Doctors Laboratory, Royal Free Hospital, Laboratoire Pasteur Cerba, University of Virginia and 3 more.
Type: Comparative Study | Journal: European journal of cancer (Oxford, England : 1990) | Year: 2014

To compare triage strategies using different human papillomavirus (HPV) consensus and genotyping tests and a p16(INK4a) test.1228 women referred with a borderline or single mildly dyskaryotic smear. Samples were taken at colposcopy using PreservCyt. Tests included Hybrid Capture 2, Abbott RealTime PCR, BD HPV, Cobas 4800, PreTect HPV-Proofer, APTIMA and p16(INK4a). Results were based on the worst histology within 9 months.97/1228 (7.9%) women had CIN3+ (203/1228 (17%) CIN2+). HPV testing alone using Hybrid Capture 2, Abbott RealTime PCR, BD HPV, Cobas 4800 or APTIMA had a sensitivity for CIN3+ ranging from 99.0% to 100.0% and specificity for


SMi Group reports: World Courier, Finnair, MHRA, IATA, Teva, GSK, J&J, Sanofi will meet in London this December at Cold Chain Distribution 2016 London, United Kingdom, November 17, 2016 --( 11th annual Cold Chain Distribution, taking place in London, UK, on the 12th and 13th of December, brings together 100+ representatives from big pharma, biotech and service providers with responsibilities in supply chain, cold chain, logistics, distribution, packaging, operations, production, manufacturing, QA and QC from Austria, Belgium, Denmark, Finland, France, Ireland, Israel, Netherlands, Switzerland, United Kingdom and other countries to keep abreast of cold chain distribution developments! Further information available at www.coldchain-distribution.com/PRCom Cold Chain Distribution 2016 speaker line up includes key decision makers and leading pharma cold chain experts representing MHRA, Danish Medicines Agency, IATA, NHS Blood & Transplant, Sanofi-Aventis, Johnson & Johnson, GlaxoSmithKline, GSK Biologicals, Teva Pharmaceutical, The Grimsby Institute, World Courier, Finnair Cargo, PCI Pharma Services, Cell and Gene Therapy Catapult, Modalis, Exelsius, Vertex International Ltd and more. The complete 2-day event programme including all speakers and their topics can be viewed at www.coldchain-distribution.com/PRCom “The aviation industry has made improvements for cold chain distribution, despite improvements there are still challenges that remain unanswered. It's time to discuss the next trends of cold chain distribution as air cargo." - Frederik Wildtgrube, Head of Global Sales, Finnair. Confirmed attendees include key decision makers from Accord Healthcare, Al Medicines, Almac Group, Avery Dennison Materials Europe B.V., BIOTRANS SA, Birmingham Children’s Hospital, Bristol-Myers Squibb, Business Unit Pharma, Catapult Cell & Gene Therapy, Cell Therapy Catapult, Copenhagen Capacity, Copenhagen Univeristy, Danish Medicines Agency, Day Lewis Plc, DBS Ltd, Eberspaecher, Envirotainer, Exelsius , Finnair Cargo, Genzyme Pharmaceuticals, GlaxoSmithKline, GSK Biologicals, GW Pharmaceuticals, IATA, Janssen Pharmaceutica N.V., JB360solutions, Johnson & Johnson, Kings College London, Kyowa Kirin International plc., Lysogene, MHRA, Modalis, MSD, NHS Blood & Transplant, Norgine Ltd, Panalpina, PCI Pharma Services, Pfizer Group, Porton Biopharma, ReNeuron, Roche Pharmaceuticals, Sanofi-Aventis, Seer Pharma, Shionogi Ltd, Shire/Global Logistics Validation, Softbox Systems Ltd, Teva Pharmaceutical, The Doctors Laboratory Ltd, The Grimsby Institute, va-Q-tec AG, Vertex Pharmaceuticals (Europe), Wockhardt UK, World Courier, Yourway Transport and many more! “We consider SMi’s Cold Chain Distribution conference as the industry-leading event in the UK which has always attracted a good mix and level of speakers and delegates, including both our customers and suppliers, who are all key opinion leaders in their respective fields. It serves as a good platform for us to engage with attendees, share best practices and challenge our theories on the future of temperature controlled distribution. As cold chain distribution is our core business, it’s imperative that we continue to evolve in accordance with the needs of our customers.” -David Spillett, Key Account Director, World Courier. Further information available at www.coldchain-distribution.com/PRCom Cold Chain Distribution 2016 offers to its attendees a fantastic networking opportunity with the leading experts in the industry at a drinks reception on day one followed by a Gala Dinner (invitation only) hosted by World Courier. Cold Chain Distribution 2016 is proud to be sponsored by the leading service providers including: World Courier (Lead Sponsor), Berlinger & Co. AG, Eberspächer, ELPRO, Emball'iso, Finnair Cargo, Peli BioThermal, Sensitech, SMO Group, Testo Limited, Topa Thermal, va-Q-tech and Yourway Transport. 11th Annual Cold Chain Distribution Conference and Exhibition Park Plaza Victoria, London, UK 12th-13th December, 2016 www.coldchain-distribution.com/PRCom Sponsors/Exhibitors: Contact Alia Malick at +44 (0) 7827 6168, amalick@smi-online.co.uk Delegates/Groups: Contact Fateja Begum at +44 (0) 20 7827 6184, fbegum@smi-online.co.uk Media Enquiries: Contact Julia Rotar at jrotar@smi-online.co.uk About SMi Group: Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world’s most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at http://www.smi-online.co.uk London, United Kingdom, November 17, 2016 --( PR.com )-- Over the last 24 months, new logistics hubs have been established around the globe by forwarders and distributors, in order to service and support a more round-the-clock global network for pharmaceutical product supply. Nonetheless, challenges remain with the increasingly fragile biologics product and tightened GDP regulations.11th annual Cold Chain Distribution, taking place in London, UK, on the 12th and 13th of December, brings together 100+ representatives from big pharma, biotech and service providers with responsibilities in supply chain, cold chain, logistics, distribution, packaging, operations, production, manufacturing, QA and QC from Austria, Belgium, Denmark, Finland, France, Ireland, Israel, Netherlands, Switzerland, United Kingdom and other countries to keep abreast of cold chain distribution developments!Further information available at www.coldchain-distribution.com/PRComCold Chain Distribution 2016 speaker line up includes key decision makers and leading pharma cold chain experts representing MHRA, Danish Medicines Agency, IATA, NHS Blood & Transplant, Sanofi-Aventis, Johnson & Johnson, GlaxoSmithKline, GSK Biologicals, Teva Pharmaceutical, The Grimsby Institute, World Courier, Finnair Cargo, PCI Pharma Services, Cell and Gene Therapy Catapult, Modalis, Exelsius, Vertex International Ltd and more.The complete 2-day event programme including all speakers and their topics can be viewed at www.coldchain-distribution.com/PRCom“The aviation industry has made improvements for cold chain distribution, despite improvements there are still challenges that remain unanswered. It's time to discuss the next trends of cold chain distribution as air cargo." - Frederik Wildtgrube, Head of Global Sales, Finnair.Confirmed attendees include key decision makers from Accord Healthcare, Al Medicines, Almac Group, Avery Dennison Materials Europe B.V., BIOTRANS SA, Birmingham Children’s Hospital, Bristol-Myers Squibb, Business Unit Pharma, Catapult Cell & Gene Therapy, Cell Therapy Catapult, Copenhagen Capacity, Copenhagen Univeristy, Danish Medicines Agency, Day Lewis Plc, DBS Ltd, Eberspaecher, Envirotainer, Exelsius , Finnair Cargo, Genzyme Pharmaceuticals, GlaxoSmithKline, GSK Biologicals, GW Pharmaceuticals, IATA, Janssen Pharmaceutica N.V., JB360solutions, Johnson & Johnson, Kings College London, Kyowa Kirin International plc., Lysogene, MHRA, Modalis, MSD, NHS Blood & Transplant, Norgine Ltd, Panalpina, PCI Pharma Services, Pfizer Group, Porton Biopharma, ReNeuron, Roche Pharmaceuticals, Sanofi-Aventis, Seer Pharma, Shionogi Ltd, Shire/Global Logistics Validation, Softbox Systems Ltd, Teva Pharmaceutical, The Doctors Laboratory Ltd, The Grimsby Institute, va-Q-tec AG, Vertex Pharmaceuticals (Europe), Wockhardt UK, World Courier, Yourway Transport and many more!“We consider SMi’s Cold Chain Distribution conference as the industry-leading event in the UK which has always attracted a good mix and level of speakers and delegates, including both our customers and suppliers, who are all key opinion leaders in their respective fields. It serves as a good platform for us to engage with attendees, share best practices and challenge our theories on the future of temperature controlled distribution. As cold chain distribution is our core business, it’s imperative that we continue to evolve in accordance with the needs of our customers.” -David Spillett, Key Account Director, World Courier.Further information available at www.coldchain-distribution.com/PRComCold Chain Distribution 2016 offers to its attendees a fantastic networking opportunity with the leading experts in the industry at a drinks reception on day one followed by a Gala Dinner (invitation only) hosted by World Courier.Cold Chain Distribution 2016 is proud to be sponsored by the leading service providers including: World Courier (Lead Sponsor), Berlinger & Co. AG, Eberspächer, ELPRO, Emball'iso, Finnair Cargo, Peli BioThermal, Sensitech, SMO Group, Testo Limited, Topa Thermal, va-Q-tech and Yourway Transport.11th Annual Cold Chain Distribution Conference and ExhibitionPark Plaza Victoria, London, UK12th-13th December, 2016www.coldchain-distribution.com/PRComSponsors/Exhibitors: Contact Alia Malick at +44 (0) 7827 6168, amalick@smi-online.co.ukDelegates/Groups: Contact Fateja Begum at +44 (0) 20 7827 6184, fbegum@smi-online.co.ukMedia Enquiries: Contact Julia Rotar at jrotar@smi-online.co.ukAbout SMi Group:Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world’s most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at http://www.smi-online.co.uk Click here to view the list of recent Press Releases from SMi Group


Pharma Cold Chain Distribution: Big Pharma, MHRA and Leading Logistics Companies to Meet in London This December at SMi's Cold Chain Distribution SMi Group reports: World Courier, Finnair, MHRA, IATA, Teva, GSK, J&J, Sanofi will meet in London this December at Cold Chain Distribution 2016. London, United Kingdom, November 30, 2016 --( Just a fortnight remains until the SMi Group opens their doors to host the 11th annual conference on Cold Chain Distribution. This year’s event will bring over 120 attendees from all over the world including senior representatives from big pharma, biotech and service providers with responsibilities in supply chain, cold chain, logistics, distribution, packaging, operations, production, manufacturing, QA and QC from Austria, Belgium, Denmark, Finland, France, Ireland, Israel, Netherlands, Switzerland, United Kingdom and other countries to keep abreast of cold chain distribution developments. Further information available at www.coldchain-distribution.com/PrCom. Cold Chain Distribution 2016 speaker line up includes key decision makers and leading pharma cold chain experts representing MHRA, Danish Medicines Agency, IATA, NHS Blood & Transplant, Sanofi-Aventis, Johnson & Johnson, GlaxoSmithKline, GSK Biologicals, Teva Pharmaceutical, The Grimsby Institute, World Courier, Finnair Cargo, PCI Pharma Services, Cell and Gene Therapy Catapult, Modalis, Exelsius, Vertex International Ltd and more. The complete 2-day event programme including all speakers and their topics can be viewed at www.coldchain-distribution.com/PrCom. "The aviation industry has made improvements for cold chain distribution, despite improvements there are still challenges that remain unanswered. It's time to discuss the next trends of cold chain distribution as air cargo." - Frederik Wildtgrube, Head of Global Sales, Finnair Confirmed attendees include key decision makers from Accord Healthcare, Actelion Pharmaceuticals UK, Al Medicines, Alliance Healthcare, Almac Group, Avery Dennison Materials Europe B.V., BIOTRANS SA, Birmingham Children’s Hospital, Bristol-Myers Squibb, Brussels Airport Company, Business Unit Pharma, Catapult Cell & Gene Therapy, Cell Therapy Catapult, Copenhagen Capacity, Copenhagen Univeristy, Danish Medicines Agency, Day Lewis Plc, DBS Ltd, Eberspaecher, Eli Lilly Italia SpA, Envirotainer, Exelsius, Finnair Cargo, Genzyme Pharmaceuticals, GlaxoSmithKline, GSK Biologicals, GW Pharmaceuticals, IATA, Janssen Pharmaceutica N.V., JB360solutions, Johnson & Johnson, Kings College London, Kyowa Kirin International plc., Lysogene, MHRA, Modalis, MSD, NHS Blood & Transplant, Norgine Ltd, Novartis Business Services, Panalpina, PCI Pharma Services, Pfizer Group, Porton Biopharma, ReNeuron, Roche Pharmaceuticals, Sanofi-Aventis, Seer Pharma, Shionogi Ltd, Shire/Global Logistics Validation, Softbox Systems Ltd, Teva Pharmaceutical, The Doctors Laboratory Ltd, The Grimsby Institute, va-Q-tec AG, Vertex Pharmaceuticals (Europe), Wockhardt UK, World Courier, Yourway Transport and many more. “We consider SMi’s Cold Chain Distribution conference as the industry-leading event in the UK which has always attracted a good mix and level of speakers and delegates, including both our customers and suppliers, who are all key opinion leaders in their respective fields. It serves as a good platform for us to engage with attendees, share best practices and challenge our theories on the future of temperature controlled distribution. As cold chain distribution is our core business, it’s imperative that we continue to evolve in accordance with the needs of our customers.” - David Spillett, Key Account Director, World Courier Further information available at www.coldchain-distribution.com/PrCom. Cold Chain Distribution 2016 offers to its attendees a fantastic networking opportunity with the leading experts in the industry at a drinks reception on day one followed by a Gala Dinner (invitation only) hosted by World Courier. Cold Chain Distribution 2016 is proud to be sponsored by the leading service providers including: World Courier (Lead Sponsor), Berlinger & Co. AG, Eberspächer, ELPRO, Emball'iso, Finnair Cargo, NEFTAG, Peli BioThermal, Sensitech, SMO Group, Testo Limited, Topa Thermal, va-Q-tech and Yourway Transport. 11th Annual Cold Chain Distribution Conference and Exhibition Park Plaza Victoria, London, UK 12th-13th December, 2016 www.coldchain-distribution.com/PrCom Sponsors/Exhibitors: Contact Alia Malick on amalick@smi-online.co.uk Delegates/Groups: Contact Fateja Begum on fbegum@smi-online.co.uk Media Enquiries: Contact Julia Rotar on jrotar@smi-online.co.uk About SMi Group: Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world’s most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at http://www.smi-online.co.uk. London, United Kingdom, November 30, 2016 --( PR.com )-- Over the last 24 months, the new logistics hubs have been established around the globe by forwarders and distributors, in order to service and support a more round-the-clock global network for pharmaceutical product supply. Nonetheless, challenges remain with the increasingly fragile biologics product and tightened GDP regulations.Just a fortnight remains until the SMi Group opens their doors to host the 11th annual conference on Cold Chain Distribution. This year’s event will bring over 120 attendees from all over the world including senior representatives from big pharma, biotech and service providers with responsibilities in supply chain, cold chain, logistics, distribution, packaging, operations, production, manufacturing, QA and QC from Austria, Belgium, Denmark, Finland, France, Ireland, Israel, Netherlands, Switzerland, United Kingdom and other countries to keep abreast of cold chain distribution developments.Further information available at www.coldchain-distribution.com/PrCom.Cold Chain Distribution 2016 speaker line up includes key decision makers and leading pharma cold chain experts representing MHRA, Danish Medicines Agency, IATA, NHS Blood & Transplant, Sanofi-Aventis, Johnson & Johnson, GlaxoSmithKline, GSK Biologicals, Teva Pharmaceutical, The Grimsby Institute, World Courier, Finnair Cargo, PCI Pharma Services, Cell and Gene Therapy Catapult, Modalis, Exelsius, Vertex International Ltd and more.The complete 2-day event programme including all speakers and their topics can be viewed at www.coldchain-distribution.com/PrCom."The aviation industry has made improvements for cold chain distribution, despite improvements there are still challenges that remain unanswered. It's time to discuss the next trends of cold chain distribution as air cargo." - Frederik Wildtgrube, Head of Global Sales, FinnairConfirmed attendees include key decision makers from Accord Healthcare, Actelion Pharmaceuticals UK, Al Medicines, Alliance Healthcare, Almac Group, Avery Dennison Materials Europe B.V., BIOTRANS SA, Birmingham Children’s Hospital, Bristol-Myers Squibb, Brussels Airport Company, Business Unit Pharma, Catapult Cell & Gene Therapy, Cell Therapy Catapult, Copenhagen Capacity, Copenhagen Univeristy, Danish Medicines Agency, Day Lewis Plc, DBS Ltd, Eberspaecher, Eli Lilly Italia SpA, Envirotainer, Exelsius, Finnair Cargo, Genzyme Pharmaceuticals, GlaxoSmithKline, GSK Biologicals, GW Pharmaceuticals, IATA, Janssen Pharmaceutica N.V., JB360solutions, Johnson & Johnson, Kings College London, Kyowa Kirin International plc., Lysogene, MHRA, Modalis, MSD, NHS Blood & Transplant, Norgine Ltd, Novartis Business Services, Panalpina, PCI Pharma Services, Pfizer Group, Porton Biopharma, ReNeuron, Roche Pharmaceuticals, Sanofi-Aventis, Seer Pharma, Shionogi Ltd, Shire/Global Logistics Validation, Softbox Systems Ltd, Teva Pharmaceutical, The Doctors Laboratory Ltd, The Grimsby Institute, va-Q-tec AG, Vertex Pharmaceuticals (Europe), Wockhardt UK, World Courier, Yourway Transport and many more.“We consider SMi’s Cold Chain Distribution conference as the industry-leading event in the UK which has always attracted a good mix and level of speakers and delegates, including both our customers and suppliers, who are all key opinion leaders in their respective fields. It serves as a good platform for us to engage with attendees, share best practices and challenge our theories on the future of temperature controlled distribution. As cold chain distribution is our core business, it’s imperative that we continue to evolve in accordance with the needs of our customers.” - David Spillett, Key Account Director, World CourierFurther information available at www.coldchain-distribution.com/PrCom.Cold Chain Distribution 2016 offers to its attendees a fantastic networking opportunity with the leading experts in the industry at a drinks reception on day one followed by a Gala Dinner (invitation only) hosted by World Courier.Cold Chain Distribution 2016 is proud to be sponsored by the leading service providers including: World Courier (Lead Sponsor), Berlinger & Co. AG, Eberspächer, ELPRO, Emball'iso, Finnair Cargo, NEFTAG, Peli BioThermal, Sensitech, SMO Group, Testo Limited, Topa Thermal, va-Q-tech and Yourway Transport.11th Annual Cold Chain Distribution Conference and ExhibitionPark Plaza Victoria, London, UK12th-13th December, 2016www.coldchain-distribution.com/PrComSponsors/Exhibitors: Contact Alia Malick on amalick@smi-online.co.uk Delegates/Groups: Contact Fateja Begum on fbegum@smi-online.co.ukMedia Enquiries: Contact Julia Rotar on jrotar@smi-online.co.ukAbout SMi Group:Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world’s most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at http://www.smi-online.co.uk. Click here to view the list of recent Press Releases from SMi Group


Smelov V.,Karolinska Institutet | Smelov V.,Saint Petersburg State University | Arroyo Muhr L.S.,Karolinska Institutet | Bzhalava D.,Karolinska Institutet | And 3 more authors.
Journal of Medical Virology | Year: 2014

To investigate which microorganisms may be present in expressed prostate secretions (EPS) metagenomic sequencing (MGS) was applied to prostate secretion samples from five men with prostatitis and five matched control men as well as to combined expressed prostate secretion and urine from six patients with prostate cancer and six matched control men. The prostate secretion samples contained a variety of bacterial sequences, mostly belonging to the Proteobacteria phylum. The combined prostate secretion and urine samples were dominated by abundant presence of the JC polyomavirus, representing >20% of all detected metagenomic sequence reads. There were also other viruses detected, for example, human papillomavirus type 81. All combined prostate secretion and urine samples were also positive for Proteobacteria. In summary, MGS of expressed prostate secretion is informative for detecting a variety of bacteria and viruses, suggesting that a more large-scale use of MGS of prostate secretions may be useful in medical and epidemiological studies of prostate infections. J. Med. Virol. 86:2042-2048, 2014. © 2014 Wiley Periodicals, Inc.


Smelov V.,Karolinska Institutet | Smelov V.,North State Medical University | Novikov A.,North State Medical University | Brown L.J.,The Doctors Laboratory | And 6 more authors.
International Journal of STD and AIDS | Year: 2013

Symptomatic male urethral Chlamydia trachomatis infection resulted in inflammation of the prostate, with associated increases in both prostate-specific (PSA) and prostate cancer-specific (PCA3) markers with prostate biopsies showing no evidence of malignancy. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.


Homa S.T.,The Doctors Laboratory | Vessey W.,The Doctors Laboratory | Perez-Miranda A.,The Doctors Laboratory | Riyait T.,The Doctors Laboratory | Agarwal A.,Cleveland Clinic
Journal of Assisted Reproduction and Genetics | Year: 2015

Purpose: High levels of reactive oxygen species (ROS) are a leading cause of male factor infertility. Measurement of ROS has been hampered by a lack of standardisation and confounding variables including choice of controls and sample selection. This study aimed to determine a reference range for ROS in human semen. Methods: Semen samples were obtained from men attending for routine semen analysis who gave informed consent for the study. Samples were assigned groups: Group 1 (N = 94) normal semen parameters, no leucocytospermia; Group 2 (N = 100) abnormal semen parameters, no leucocytospermia; Group 3 (N = 41) any semen parameters with leucocytospermia. ROS levels were assayed in fresh neat semen using a chemiluminescence assay measured in a single tube luminometer. Data are reported in relative light units (RLU)/sec/106 sperm Results: ROS levels were significantly different between Groups 1, 2 and 3 (19.75 ± 8.12, 95.03 ± 33.63, 890.17 ± 310.23 RLU/sec/106 sperm respectively; p < 0.001). Group 3 gave the highest value confirming this group as the optimum choice for positive controls. The reference range < 24.1 RLU/sec/106 sperm was determined by ROC analysis that differentiates a reference population (Group 1) from a positive control group (Group 3), optimising the sensitivity and specificity (80.5 and 87.2 % respectively) of the test. Conclusions: We have determined a reference range for ROS in human semen and identified a patient population that falls outside the normal range. This simple, cost effective assay can be incorporated into routine diagnostic testing to aid in the diagnosis of male infertility, especially with regard to unexplained infertility. © 2015, Springer Science+Business Media New York.

Loading The Doctors Laboratory collaborators
Loading The Doctors Laboratory collaborators