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Duluth, MN, United States

The College of Saint Scholastica is a private college with its main campus located in Duluth, Minnesota, United States. Today St. Scholastica educates more than 4,000 students annually and has graduated more than 13,000 alumni.U.S. News & World Report ranks St. Scholastica in the Top Tier of regional universities in the Midwest. Wikipedia.

Donovan M.L.,The College of St. Scholastica | Corcoran M.A.,George Washington University | Corcoran M.A.,Shenandoah University
American Journal of Occupational Therapy | Year: 2010

OBJECTIVE. Most occupational therapy interventions for caregivers are designed to reduce negative consequences of caregiving by building skills to manage problem behaviors and dependence. However, therapists may be missing an opportunity to provide interventions that directly help caregivers to emphasize and act on positive aspects of care. We describe care-related thinking and action processes of long-term caregivers who report positive effects related to caring for a spouse with dementia. METHOD. We analyzed data from 15 experienced and uplifted (reporting improved well-being from caregiving) spouse caregivers to describe how they think about and carry out their care duties. RESULTS. We describe two primary themes of caregiver thinking and action: (1) engaging in positive behaviors and (2) making adjustments in attitudes. CONCLUSION. These findings support a new focus for occupational therapy caregiver intervention that promotes a positive approach to thinking about and enacting care tasks.

Gibbons T.E.,The College of St. Scholastica
SIGITE 2013 - Proceedings of the 2013 ACM SIGITE Annual Conference on Information Technology Education | Year: 2013

Taking cues from the root causes of anxiety and poor student performance, a new course framework is developed using three key elements of game play. These game play elements are abstracted into an integrated teaching framework that gives students a choice in actions, options for cooperation and competition, and allows for revisions of work. Two case studies are examined that demonstrate how this framework can be implemented. One shows how this framework can be incorporated in the final project of a systems analysis and design course. The other shows how the framework can be used in a game design course to prepare students for different career paths. © 2013 ACM.

Zhang J.,University of North Carolina at Chapel Hill | Sapienza P.J.,University of North Carolina at Chapel Hill | Ke H.,University of North Carolina at Chapel Hill | Chang A.,University of Wisconsin - Madison | And 4 more authors.
Biochemistry | Year: 2010

PDZ (PSD95/Discs large/ZO-1) domains are ubiquitous protein interaction motifs found in scaffolding proteins involved in signal transduction. Despite the fact that many PDZ domains show a limited tendency to undergo structural change, the PDZ family has been associated with long-range communication and allostery. One of the PDZ domains studied most in terms of structure and biophysical properties is the second PDZ ("PDZ2") domain from protein tyrosine phosphatase 1E (PTP1E, also known as PTPL1). Previously, we showed through NMR relaxation studies that binding of the RA-GEF2 C-terminal peptide substrate results in long-range propagation of side-chain dynamic changes in human PDZ2 [Fuentes, E. J., et al. (2004) J. Mol. Biol. 335, 1105-1115]. Here, we present the first X-ray crystal structures of PDZ2 in the absence and presence of RA-GEF2 ligand, determined to resolutions of 1.65 and 1.3 Å, respectively. These structures deviate somewhat from previously determined NMR structures and indicate that very minor structural changes in PDZ2 accompany peptide binding. NMR residual dipolar couplings confirm the crystal structures to be accurate models of the time-averaged atomic coordinates of PDZ2. The impact on side-chain dynamics was further tested with a C-terminal peptide from APC, which showed results nearly identical to those of RA-GEF2. Thus, allosteric transmission in PDZ2 induced by peptide binding is conveyed purely and robustly by dynamics. 15N relaxation dispersion measurements did not detect appreciable populations of a kinetic structural intermediate. Collectively, for ligand binding to PDZ2, these data support a lock-and-key binding model from a structural perspective and an allosteric model from a dynamical perspective, which together suggest a complex energy landscape for functional transitions within the ensemble. © 2010 American Chemical Society.

Miller B.P.,University of Michigan | Miller B.P.,Macalester College | Miller B.P.,The College of St. Scholastica | Gallo E.,University of Michigan | And 2 more authors.
Astrophysical Journal | Year: 2015

We investigate whether magnetic interaction between close-in giant planets and their host stars produce observable statistical enhancements in stellar coronal or chromospheric activity. New Chandra observations of 12 nearby (d < 60 pc) planet-hosting solar analogs are combined with archival Chandra, XMM-Newton, and ROSAT coverage of 11 similar stars to construct a sample inoculated against inherent stellar class and planet-detection biases. Survival analysis and Bayesian regression methods (incorporating both measurements errors and X-ray upper limits; 13/23 stars have secure detections) are used to test whether "hot Jupiter" hosts are systematically more X-ray luminous than comparable stars with more distant or smaller planets. No significant correlations are present between common proxies for interaction strength (M P/a 2 or 1/a) versus coronal activity (L X or L X/L bol). In contrast, a sample of 198 FGK main-sequence stars does show a significant (99% confidence) increase in X-ray luminosity with M P/a 2. While selection biases are incontrovertibly present within the main-sequence sample, we demonstrate that the effect is primarily driven by a handful of extreme hot-Jupiter systems with M P/a 2 > 450 M Jup AU-2, which here are all X-ray luminous but to a degree commensurate with their Ca II H and K activity, in contrast to presented magnetic star-planet interaction scenarios that predict enhancements relatively larger in L X. We discuss these results in the context of cumulative tidal spin-up of stars hosting close-in gas giants (potentially followed by planetary infall and destruction). We also test our main-sequence sample for correlations between planetary properties and UV luminosity or Ca II H and K emission, and find no significant dependence. © 2015. The American Astronomical Society. All rights reserved.

Freeman P.L.,The College of St. Scholastica | Bachman G.C.,University of Nebraska - Lincoln
American Midland Naturalist | Year: 2016

This study documents the causes of mortality of juveniles in a declining population of thirteen-lined ground squirrels (Ictidomys tridecemlineatus). We found a dramatic decline in juvenile numbers between emergence from the natal burrow and the onset of hibernation. From 2005 to 2007, an average 70.6% of all juveniles disappeared from the population (n = 168 males and 224 females), including a 72.0% loss of males and 65.2% loss of females (χ21 = 2.1, P > 0.10). Weekly loss of juvenile males peaked 3-4 w after emergence while female loss remained relatively stable through summer. Radio-tracking enabled us to eliminate dispersal as a cause of the decline in juvenile numbers. Predation accounted for at least 71.4% of mortalities in radio-collared juveniles (66.7% of males and 76.0% of females; χ21 = 0.087, P > 0.75). We found no sex differences in specific behaviors that could predispose one sex to predation, but males were less wary than females in response to a potentially frightening stimulus.

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