The Affiliated Peoples Hospital Guiyang Medical College

Guiyang, China

The Affiliated Peoples Hospital Guiyang Medical College

Guiyang, China

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Jian Y.,The Affiliated Peoples Hospital Guiyang Medical College | Tian X.,The Affiliated Peoples Hospital Guiyang Medical College | Li B.,The Affiliated Peoples Hospital Guiyang Medical College | Zhou Z.,The Affiliated Peoples Hospital Guiyang Medical College | Wu X.,The Affiliated Peoples Hospital Guiyang Medical College
Tumor Biology | Year: 2015

With great interest, we read the article “ERCC polymorphisms and prognosis of patients with osteosarcoma” (by Li JS et al.), which has reached important conclusions about the relationship between ERCC polymorphisms and osteosarcoma prognosis. Through quantitative analysis, the meta-analysis showed that ERCC2 Lys751Gln (ORGG vs. AA = 0.40 (95%CI = 0.1–0.86), Pheterogeneity = 0.502; I2 = 0 %) and ERCC5 His46His (ORCC vs. TT = 0.37 (95%CI = 0.15–0.93), Pheterogeneity = 0.569; I2 = 0 %) polymorphisms might influence the prognosis of patients with osteosarcoma [1]. The meta-analysis results are encouraging. Nevertheless, some deficiencies still existed that we would like to raise. © 2015, International Society of Oncology and BioMarkers (ISOBM).


PubMed | The Affiliated Peoples Hospital Guiyang Medical College
Type: Comment | Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine | Year: 2015

With great interest, we read the article ERCC polymorphisms and prognosis of patients with osteosarcoma (by Li JS et al.), which has reached important conclusions about the relationship between ERCC polymorphisms and osteosarcoma prognosis. Through quantitative analysis, the meta-analysis showed that ERCC2 Lys751Gln (ORGG vs. AA = 0.40 (95%CI = 0.1-0.86), P heterogeneity = 0.502; I (2)= 0 %) and ERCC5 His46His (ORCC vs. TT = 0.37 (95%CI = 0.15-0.93), P heterogeneity = 0.569; I (2)= 0 %) polymorphisms might influence the prognosis of patients with osteosarcoma [1]. The meta-analysis results are encouraging. Nevertheless, some deficiencies still existed that we would like to raise.

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