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Ahmed N.A.,Thai Moogambigai Dental College | Jacob C.A.,Saveetha Dental College | Nittla P.P.,Saveetha Dental College
Journal of Clinical and Diagnostic Research | Year: 2017

This case report records the replacement of two failed endodontically treated mandibular molars with one piece zirconia implants in a patient with metal hypersensitivity. The two molars were atraumatically extracted and curetted to remove any remnants of a periapical granuloma. Immediate implant placement with primary stability was achieved using one piece WhiteSky® Bredent zirconia implants which were restored after four months with a zirconia crown. One year follow up revealed successful osseointegration with optimal form and function. © 2017, Journal of Clinical and Diagnostic Research. All rights reserved.


PubMed | Kasturba Medical College and Thai Moogambigai Dental College
Type: Journal Article | Journal: Journal of maxillofacial and oral surgery | Year: 2015

To evaluate the effects of topical hemocoagulase on intra-oral extraction sockets and impact on the healing process as well as to produce a clinico-histological healing score.This prospective study compared two extraction sites in each subject. One site received topical hemocoagulase while other site did not receive it. Both the sites were chosen in the same patient and extraction was done at separate intervals. The biopsy was done on a random basis with the pathologist being blinded to the study. Clinical evaluation was done on days 7, 14 and 21. Biopsy was done either on days 7 or 14 for the case as well as for the control. A clinical as well as histological score was developed and the healing was assessed. Statistical analysis was done using Wilcoxon signed rank test and p value 0.05 was considered significant and z-score was also calculated.The clinical score did not show any statistical significance. The histological total score on day 14 and combined overall analysis of days 7 and 14 showed statistical significance. There was an increased incidence (n=4) of osteoid formation in the hemocoagulase group on day 14.The application of hemocoagulase may improve and accelerates the process of wound healing in extraction sockets.


Ahmed N.,Thai Moogambigai Dental College | Mony G.,SRM University | Parthasarthy H.,SRM University
Journal of Natural Science, Biology and Medicine | Year: 2014

External cervical resorption (ECR) is the loss of dental hard tissue as a result of odontoclastic action; it usually begins on the cervical region of the root surface of the teeth. The etiology, predisposing factors, diagnosis, and management of ECR have been reviewed here. Effective management and appropriate treatment can only be carried out if the true nature and exact location of the ECR lesion are known. This paper reports on the management of a case of external cervical root resorption (ECRR), which involved root canal treatment and removal of the resorbing area of the affected tooth as well as filling the resorbed area with mineral trioxide aggregate (MTA) and resin-modified glass ionomer filling material (RMGIC). The defect was filled with bone graft material and guided tissue regeneration (GTR) membrane. This case highlights the importance of using MTA and successful management of cervical resorption with a stable uneventful clinical recovery.


PubMed | Thai Moogambigai Dental College and Dean College
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2015

Periodontitis, is an inflammatory state of the tooth supporting structures and if left untreated, the disease continues to progressive bone destruction and subsequent tooth loss. The increasing prevelance of periodontal disease paved way to the development of new diagnostic tests that could detect the presence of active disease,the course of the disease and its response to treatment. Bone is a metabolically active tissue and undergo continuous remodelling, a process that largely relies on the activity of osteoclasts to remove bone and of osteoblasts to form bone. In health ,bone resorption and formation are coupled to each other and its long term maintenance of skeletal balance is brought about by the systemic hormones and local mediators.In contrasts,during disease there is a pronounced in balance in bone turnover. Bone biomarkers which are produced either in health or in disease state are tell tale markers which would be used to monitor the health status. This review highlights, the recent advances in the use of biomarkers of bone remodelling,that could facilitate the screening, diagnosis and management of periodontal diseases.


PubMed | Research Scholar and Thai Moogambigai Dental College
Type: Journal Article | Journal: Journal of pharmacy & bioallied sciences | Year: 2015

This study was taken up to compare the antimicrobial effect of few herbal dentifrices against cariogenic organism such as Streptococcus mutans and Lactobacillus acidophilus.This study was an in vitro model using the well method of microbial culture. Colgate total was used as the positive control and distilled water as the negative control. Dentifrices were prepared in 1:1 dilution using sterile distilled water. The standard strains were inoculated and incubated for 4 h. They were then lawn cultured. Wells were made using a standard template, and the dentifrices were placed in these wells Kruskal-Wallis test and Mann-Whitney test were used for statistical analysis.In case of S. mutans, the maximum antimicrobial effect among the six dentifrices was shown by Babool followed by Colgate Herbal. For L. acidophilus, the antimicrobial zone exhibited by all the six dentifrices were similar to the positive control.Babool and Colgate Herbal have more inhibitory effect against S. mutans than the other dentifrices of the group. Dabur Red, Colgate Herbal, and Himalaya are efficient against L. acidophilus.


Shankar Ram V.,Thai Moogambagi Dental College | Parthiban,Thai Moogambagi Dental College | Sudhakar U.,Thai Moogambagi Dental College | Mithradas N.,Thai Moogambagi Dental College | Prabhakar R.,Thai Moogambigai Dental College
Journal of Clinical and Diagnostic Research | Year: 2015

Periodontitis, is an inflammatory state of the tooth supporting structures and if left untreated, the disease continues to progressive bone destruction and subsequent tooth loss. The increasing prevelance of periodontal disease paved way to the development of new diagnostic tests that could detect the presence of active disease,the course of the disease and its response to treatment. Bone is a metabolically active tissue and undergo continuous remodelling, a process that largely relies on the activity of osteoclasts to remove bone and of osteoblasts to form bone. In health,bone resorption and formation are coupled to each other and its long term maintenance of skeletal balance is brought about by the systemic hormones and local mediators.In contrasts,during disease there is a pronounced in balance in bone turnover. Bone biomarkers which are produced either in health or in disease state are tell tale markers which would be used to monitor the health status. This review highlights, the recent advances in the use of biomarkers of bone remodelling,that could facilitate the screening, diagnosis and management of periodontal diseases. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved.


Arunachalam L.T.,Thai Moogambigai Dental College | Rao S.,Sri Ramachandra University
Indian Journal of Dental Research | Year: 2013

Background: Drug-induced gingival overgrowth (DIGO) is one of the unwanted side effects of amlodipine therapy, but the pathogenesis still remains unclear. Apoptosis, which plays a ubiquitous role in tissue homeostasis, including gingiva, may be involved in the development of gingival enlargement. Aims and Objectives: (i) To study the distribution of Bcl-2 in healthy and overgrown gingival tissues. (ii) To compare and correlate the Bcl-2 expression in gingival samples from subjects on amlodipine therapy to the findings in healthy controls. Materials and Methods: A total of 25 subjects were recruited for the study - 15 hypertensive patients and 10 systemically healthy subjects. Both the groups were analyzed for Bcl-2 expression using immunohistochemistry. Results: Few of the control specimens showed weak positivity to Bcl-2 antibody, with the distribution limited to the basal cell layers alone, whereas 10 hyperplastic specimens expressed Bcl-2 and, unlike the control group, the distribution pattern was seen in both basal and suprabasal layers. Conclusion: The results indicate that the pathogenesis of amlodipine-induced gingival overgrowth might involve inhibition of apoptosis, especially with morphogenesis of hyperplastic gingival epithelia.


Kannan K.S.,Thai Moogambigai Dental College | Prabhakar R.,Thai Moogambigai Dental College | Saravanan R.,Thai Moogambigai Dental College | Karthikeyan,Thai Moogambigai Dental College | Rajvikram,Thai Moogambigai Dental College
Journal of Clinical and Diagnostic Research | Year: 2013

Composite Compound Odontoma is a rare odontogenic tumour most commonly occuring in the anterior region of maxilla. An 11-year-old female patient reported a complaint of missing left central incisor. Clinical and diagnostic investigation revealed an odontogenic mass in the region of 21. This rare case report appraises the clinical diagnosis, surgical and orthodontic intervention which was planned and performed for its management.


Krithika C.,Thai Moogambigai Dental College | Kota S.,Meenakshi Ammal Dental College | Gopal K.S.,Thai Moogambigai Dental College | Koteeswaran D.,Thai Moogambigai Dental College
Dentomaxillofacial Radiology | Year: 2011

A radicular cyst associated with carious teeth is a very common odontogenic lesion in the oral cavity, but calcifications in residual radicular cysts are quite rare.We report one such case where a routine pre-implant radiographic assessment revealed a mixed periapical radiopaque radiolucent lesion in the right maxillary central incisor region. Histological and radiographic studies show that there is a slow increase in the mineralized deposits within the cyst lumen with time. This becomes prominent histochemically in cystsmore than 8 years old and radiographically 6 years later, as seen in our case. In this paper we would like to highlight the importance of a residual radicular cyst with calcifications in the differential diagnosis of a mixed periapical radiopaque radiolucent lesion. © 2011 The British Institute of Radiology.


PubMed | Thai Moogambigai Dental College
Type: Review | Journal: Journal of oral biology and craniofacial research | Year: 2016

Oral cancer refers to the malignancies that occur in the oral cavity, lip and pharynx with 90% of oral cancers being squamous cell carcinomas (OSCC). OSCC has the highest mortality ratio compared to other carcinomas. Although oral cavity is easily accessible, most oral cancers are detected at a later stage leading to lower survival rates. Early detection of OSCC is a key factor in improving the prognosis and survival rate of the patient. Rapid advancement in the field of diagnosis has enabled early diagnosis of many potentially malignant conditions even before its clinical manifestations. One such diagnostic modality that has gained much relevance in the field of molecular biology has been the discovery of salivary biomarkers (DNA, RNA and protein markers). These salivary biomarkers have been shown to play a non-invasive role in the diagnosis and surveillance of oral cancer. The direct contact between the saliva and the oral cancer lesions makes it a most sensitive and specific, screening method in diagnosis, staging and follow-up. This review aims to discuss the effectiveness and the potential of salivary biomarkers as a screening tool in OSCC.

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