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Fifth Street, TX, United States

Texas Wesleyan University is a private, coeducational, liberal arts university founded by the Methodist Episcopal Church, South, in 1890. The main campus is located in the Polytechnic Heights Neighborhood of Fort Worth, Texas, United States. Its mascot is the "ram." Wikipedia.

Burgert J.M.,Texas Wesleyan University
Health Policy and Technology | Year: 2014

Provision of safe and effective anesthesia relies on an adequate and uninterrupted supply of anesthetic drugs and drugs used to manage complications throughout the perioperative period. The confluence of regulatory and communication barriers impede the ability of the pharmaceutical industry, government and healthcare institutions to effectively respond to anesthetic drug shortages. These impediments directly threaten the health and safety of patients undergoing surgical and diagnostic procedures in the United States. The most common causes of drug shortages are product or quality issues and manufacturing capacity issues.This paper presents 2 policy alternatives directed towards the most common causes of drug shortages; an FDA-operated stakeholder communication center and a public/private partnership communication center. The feasibility of the 2 alternatives was assessed against 5 criteria including population benefit, ethics and equity, cost feasibility, administrative feasibility and political feasibility. Selection of the most favorable alternative was based on the final score from a decision matrix presenting evaluation criteria weighed against each proposed alternative.The final result reveals the public/private communication center as the most feasible alternative. This is consistent with stakeholder agreement that early, accurate communication and coordination will help mitigate and prevent present and future shortages. Specifically, the public/private center will improve the current state of communication, protect proprietary information and provide stakeholders with information regarding manufacturing, supply, distribution, and business issues encouraging coordination of action to attack the root causes of drug shortages. © 2013 Fellowship of Postgraduate Medicine.

Ozaki H.,Japan Society for the Promotion of Science | Loenneke J.P.,University of Mississippi | Thiebaud R.S.,Texas Wesleyan University | Abe T.,University of Mississippi
Acta physiologica Hungarica | Year: 2015

Cycle training is widely performed as a major part of any exercise program seeking to improve aerobic capacity and cardiovascular health. However, the effect of cycle training on muscle size and strength gain still requires further insight, even though it is known that professional cyclists display larger muscle size compared to controls. Therefore, the purpose of this review is to discuss the effects of cycle training on muscle size and strength of the lower extremity and the possible mechanisms for increasing muscle size with cycle training. It is plausible that cycle training requires a longer period to significantly increase muscle size compared to typical resistance training due to a much slower hypertrophy rate. Cycle training induces muscle hypertrophy similarly between young and older age groups, while strength gain seems to favor older adults, which suggests that the probability for improving in muscle quality appears to be higher in older adults compared to young adults. For young adults, higher-intensity intermittent cycling may be required to achieve strength gains. It also appears that muscle hypertrophy induced by cycle training results from the positive changes in muscle protein net balance.

Abe T.,University of Mississippi | Loenneke J.P.,University of Mississippi | Thiebaud R.S.,Texas Wesleyan University | Loftin M.,University of Mississippi
Ultrasound | Year: 2014

Unless a subject’s muscle is relatively small, a single image from a standard ultrasound can only measure muscle thickness (MT). Thus, it is important to know whether MT is related to morphological and functional characteristics of individual muscles of the extremity and trunk. In this review, we summarize previously published articles in the upper extremity and trunk demonstrating the relationships between ultrasound-measured MT and muscle morphology (cross-sectional area, CSA and muscle volume, MV) and muscular or respiratory function. The linear relationship between MT and muscle CSA or MV has been observed in biceps brachii, triceps brachii, pectoralis major, psoas major, and supraspinatus muscles. Previous studies suggest that MT in the upper arm and trunk may reflect muscle CSA and MV for the individual muscles. Unfortunately, few studies exist regarding the functional relationship with ultrasound MT in theupper extremity and trunk. Future research is needed to investigate these findings further. ©, 2014, SAGE Publications Ltd. All reserved reserved.

Miller B.R.,Indiana University Bloomington | Miller B.R.,Texas Wesleyan University | Dorner J.L.,Indiana University Bloomington | Bunner K.D.,Indiana University Bloomington | And 4 more authors.
Journal of Neurochemistry | Year: 2012

A corticostriatal-dependent deficit in the release of ascorbate (AA), an antioxidant vitamin and neuromodulator, occurs concurrently in striatum with dysfunctional GLT1-dependent uptake of glutamate in the R6/2 mouse model of Huntington's disease (HD), an autosomal dominant condition characterized by overt corticostriatal dysfunction. To determine if deficient striatal AA release into extracellular fluid is related to altered GLT1 activity in HD, symptomatic R6/2 mice between 6 and 9 weeks of age and age-matched wild-type (WT) mice received single daily injections of 200 mg/kg ceftriaxone, a β-lactam antibiotic that elevates the functional expression of GLT1, or saline vehicle for five consecutive days. On the following day, in vivo voltammetry was coupled with corticostriatal afferent stimulation to monitor evoked release of AA into striatum. In saline-treated mice, we found a marked decrease in evoked extracellular AA in striatum of R6/2 relative to WT. Ceftriaxone, in contrast, restored striatal AA in R6/2 mice to WT levels. In addition, intra-striatal infusion of either the GLT1 inhibitor dihydrokainic acid or DL-threo-beta- benzyloxyaspartate blocked evoked striatal AA release. Collectively, our results provide compelling evidence for a link between GLT1 activation and release of AA into the striatal extracellular fluid, and suggest that dysfunction of this system is a key component of HD pathophysiology. © 2012 The Authors Journal of Neurochemistry © 2012 International Society for Neurochemistry.

Hand M.M.,Texas Wesleyan University | Thomas D.,Louisiana Tech University | Buboltz W.C.,Louisiana Tech University | Deemer E.D.,Purdue University | Buyanjargal M.,University of Houston-Downtown
Cyberpsychology, Behavior, and Social Networking | Year: 2013

Online social networks, such as Facebook, have gained immense popularity and potentially affect the way people build and maintain interpersonal relationships. The present study sought to examine time spent on online social networks, as it relates to intimacy and relationship satisfaction experienced in romantic relationships. Results did not find relationships between an individual's usage of online social networks and his/her perception of relationship satisfaction and intimacy. However, the study found a negative relationship between intimacy and the perception of a romantic partner's use of online social networks. This finding may allude to an attributional bias in which individuals are more likely to perceive a partner's usage as negative compared to their own usage. Additionally, it was found that intimacy mediates the relationship between online social network usage and overall relationship satisfaction, which suggests that the level of intimacy experienced in a relationship may serve as a buffer that protects the overall level of satisfaction. © Mary Ann Liebert, Inc.

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