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Lubbock, TX, United States

Texas Tech University, often referred to as Texas Tech, Tech, or TTU, is a public research university in Lubbock, Texas, United States. Established on February 10, 1923, and originally known as Texas Technological College, it is the leading institution of the four-institution Texas Tech University System. The university's student enrollment is the sixth-largest in the state of Texas, as of the Fall 2014 semester. The university shares its campus with Texas Tech University Health science Center, making it the only campus in Texas to house an undergraduate university, law school, and medical school at the same location.The university offers degrees in more than 150 courses of study through 13 colleges and hosts 60 research centers and institutes. Texas Tech University has awarded over 200,000 degrees since 1927, including over 40,000 graduate and professional degrees. The Carnegie Foundation classifies Texas Tech as having "high research activity". Research projects in the areas of epidemiology, pulsed power, grid computing, nanophotonics, atmospheric science, and wind energy are among the most prominent at the university. The Spanish Renaissance-themed campus, described by author James Michener as "the most beautiful west of the Mississippi until you get to Stanford", has been awarded the Grand Award for excellence in grounds-keeping, and has been noted for possessing a public art collection among the ten best in the United States.The Texas Tech Red Raiders are charter members of the Big 12 Conference and compete in Division I for all varsity sports. The Red Raiders football team has made 36 bowl appearances, which is 17th most of any university. The Red Raiders basketball team has made 14 appearances in the NCAA Division I Tournament. Bob Knight, the second-winningest coach in men's NCAA Division I basketball history, served as the team's head coach from 2001 to 2008. The Lady Raiders basketball team won the 1993 NCAA Division I Tournament. In 1999, Texas Tech's Goin' Band from Raiderland received the Sudler Trophy, which is awarded to "recognize collegiate marching bands of particular excellence".Though the majority of the university's students originate in the southwestern United States, the school has served students from all 50 states and more than 100 foreign countries. Texas Tech University alumni and former students have gone on to prominent careers in government, business, science, medicine, education, sports, and entertainment. Wikipedia.

Cooper J.A.,Texas Tech University
Nutrition Research Reviews | Year: 2014

As obesity continues to be a global epidemic, research into the mechanisms of hunger and satiety and how those signals act to regulate energy homeostasis persists. Peptide YY (PYY) is an acute satiety signal released upon nutrient ingestion and has been shown to decrease food intake when administered exogenously. More recently, investigators have studied how different factors influence PYY release and circulating levels in humans. Some of these factors include exercise, macronutrient composition of the diet, body-weight status, adiposity levels, sex, race and ageing. The present article provides a succinct and comprehensive review of the recent literature published on the different factors that influence PYY release and circulating levels in humans. Where human data are insufficient, evidence in animal or cell models is summarised. Additionally, the present review explores the recent findings on PYY responses to different dietary fatty acids and how this new line of research will make an impact on future studies on PYY. Human demographics, such as sex and age, do not appear to influence PYY levels. Conversely, adiposity or BMI, race and acute exercise all influence circulating PYY levels. Both dietary fat and protein strongly stimulate PYY release. Furthermore, MUFA appear to result in a smaller PYY response compared with SFA and PUFA. PYY levels appear to be affected by acute exercise, macronutrient composition, adiposity, race and the composition of fatty acids from dietary fat. © 2014 The Authors.

Lodewyk M.W.,University of California at Davis | Siebert M.R.,Texas Tech University | Tantillo D.J.,University of California at Davis
Chemical Reviews | Year: 2012

Key background information, examples, and more recent techniques of computational prediction of 1H and 13C chemical shifts, are presented. A major step in calculating chemical shifts is to compute the NMR isotropic shielding constants for the various nuclei in the molecule. Migda and Rys noted that subtracting computed 13C isotropic shielding constants from TMS values resulted in mean absolute errors 2-3 times greater than when they used the intercept of a linear regression plot. An option for locating conformers involves running relaxed or rigid potential energy surface scans around the various rotatable bonds in the molecule of interest. In 2007, Zhang et al. compiled optimized bond lengths and angles for small organic molecules for which experimental bond distances and angles were also available and found that even HF can reproduce bond distances to about 0.01 Å resolution and bond angles to approximately 0.5.

Hui Q.,Texas Tech University
IEEE Transactions on Automatic Control | Year: 2011

This technical note focuses on finite-time rendezvous problems which refer to agreement on states in finite time within certain available information range. Using semistability theory for discontinuous dynamical systems, we develop a framework for designing finite-time semistable rendezvous protocols for multiagent dynamical systems. Specifically, we present distributed nonsmooth static state and dynamic output feedback controller architectures for finite-time rendezvous with a novel two-step proof of stability and finite-time convergence. © 2010 IEEE.

Rock C.D.,Texas Tech University
Trends in Plant Science | Year: 2013

The facility and versatility of microRNAs (miRNAs) to evolve and change likely underlies how they have become dominant constituents of eukaryotic genomes. In this opinion article I propose that trans-acting small interfering RNA gene 4 ( TAS4) evolution may be important for biosynthesis of polyphenolics, arbuscular symbiosis, and bacterial pathogen etiologies. Expression-based and phylogenetic evidence shows that TAS4 targets two novel grape ( Vitis vinifera L.) MYB transcription factors (VvMYBA6, VvMYBA7) that spawn phased small interfering RNAs (siRNAs) which probably function in nutraceutical bioflavonoid biosynthesis and fruit development. Characterization of the molecular mechanisms of TAS4 control of plant development and integration into biotic and abiotic stress- and nutrient-signaling regulatory networks has applicability to molecular breeding and the development of strategies for engineering healthier foods. © 2013 Elsevier Ltd.

Nes W.D.,Texas Tech University
Chemical Reviews | Year: 2011

Cholesterol and its relatives possessing the 1,2- cyclopentanoperhydrophenanthrene ring system form the sterolome, which comprises a chemical library of more than 1000 natural products found in all forms of eukaryotes and some prokaryotes that serve a myriad of biological functions. Central to the advances of the past two decades is the development of molecular genetic approaches that have witnessed the cloning, primary amino acid sequences, and functional characterization of a large number of enzymes that act on sterol and revealed unexpected inborn errors of cholesterol metabolism. The relevant committed step that distinguishes sterol from isoprenoid-triterpenoid biosynthesis occurs at the cyclization of oxidosqualene. There is still much to learn about sterol biosynthesis and the enzymes involved in the pathway.

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