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Lubbock, TX, United States

Texas Tech University, often referred to as Texas Tech, Tech, or TTU, is a public research university in Lubbock, Texas, United States. Established on February 10, 1923, and originally known as Texas Technological College, it is the leading institution of the four-institution Texas Tech University System. The university's student enrollment is the sixth-largest in the state of Texas, as of the Fall 2014 semester. The university shares its campus with Texas Tech University Health science Center, making it the only campus in Texas to house an undergraduate university, law school, and medical school at the same location.The university offers degrees in more than 150 courses of study through 13 colleges and hosts 60 research centers and institutes. Texas Tech University has awarded over 200,000 degrees since 1927, including over 40,000 graduate and professional degrees. The Carnegie Foundation classifies Texas Tech as having "high research activity". Research projects in the areas of epidemiology, pulsed power, grid computing, nanophotonics, atmospheric science, and wind energy are among the most prominent at the university. The Spanish Renaissance-themed campus, described by author James Michener as "the most beautiful west of the Mississippi until you get to Stanford", has been awarded the Grand Award for excellence in grounds-keeping, and has been noted for possessing a public art collection among the ten best in the United States.The Texas Tech Red Raiders are charter members of the Big 12 Conference and compete in Division I for all varsity sports. The Red Raiders football team has made 36 bowl appearances, which is 17th most of any university. The Red Raiders basketball team has made 14 appearances in the NCAA Division I Tournament. Bob Knight, the second-winningest coach in men's NCAA Division I basketball history, served as the team's head coach from 2001 to 2008. The Lady Raiders basketball team won the 1993 NCAA Division I Tournament. In 1999, Texas Tech's Goin' Band from Raiderland received the Sudler Trophy, which is awarded to "recognize collegiate marching bands of particular excellence".Though the majority of the university's students originate in the southwestern United States, the school has served students from all 50 states and more than 100 foreign countries. Texas Tech University alumni and former students have gone on to prominent careers in government, business, science, medicine, education, sports, and entertainment. Wikipedia.

Nes W.D.,Texas Tech University
Chemical Reviews | Year: 2011

Cholesterol and its relatives possessing the 1,2- cyclopentanoperhydrophenanthrene ring system form the sterolome, which comprises a chemical library of more than 1000 natural products found in all forms of eukaryotes and some prokaryotes that serve a myriad of biological functions. Central to the advances of the past two decades is the development of molecular genetic approaches that have witnessed the cloning, primary amino acid sequences, and functional characterization of a large number of enzymes that act on sterol and revealed unexpected inborn errors of cholesterol metabolism. The relevant committed step that distinguishes sterol from isoprenoid-triterpenoid biosynthesis occurs at the cyclization of oxidosqualene. There is still much to learn about sterol biosynthesis and the enzymes involved in the pathway. Source

Disclosed is a system and method for targeted therapy designs which model a cancer pathway for predicting the effectiveness of targeted anti-cancer drugs. The disclosed system and method includes utilization of a computer processor allowing for the selection of a set of drugs from available drugs using approximation algorithms utilizing cell viability data associated with a testable culture of a patients tumor for generating a probabilistic target inhibition map (PTIM) from viability data for considering the selection of a set of drugs from available drugs, and further supports a wide variety of scenarios for personalized cancer therapy, related products and services.

The present invention includes a method for the treatment of myeloma comprising identifying a patient with myeloma and administering to the patient a synergistic, effective amount of a truncated, dominant negative form of Galectin-3 and a proteasome inhibitor.

The present invention includes a method for the treatment of myeloma comprising identifying a patient with myeloma and administering to the patient a synergistic, effective amount of a truncated, dominant negative form of Gaicctin-3 and a proteasome inhibitor.

Texas Tech University and Nanjing University | Date: 2014-03-12

Provided herein are novel chiral sulfinamide and imine compounds. Also provided herein are methods of synthesizing novel chiral sulfinamide and imine compounds comprising simplified purification methods when compared to prior methods. The novel chiral sulfinamide and imine compounds are useful, for example, in the synthesis of complex natural products and pharmaceutical important compounds.

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