Technical University of Denmark

www.dtu.dk/
Lyngby, Denmark

The Technical University of Denmark , often simply referred to as DTU, is a university in Kongens Lyngby, just north of Copenhagen, Denmark. It was founded in 1829 at the initiative of Hans Christian Ørsted as Denmark's first polytechnic, and is today ranked among Europe's leading engineering institutions, and the best engineering university in the Nordic countries. Wikipedia.

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Patent
Technical University of Denmark | Date: 2017-01-04

The present invention relates to a resonant DC-DC power converter comprising an input side circuit comprising a positive and a negative input terminal for receipt of an input voltage or current and an output side circuit comprising positive and negative output terminals for supply of a converter output voltage and connection to a converter load. The resonant DC-DC power converter further comprises a rectification circuit connected between an output of a resonant network and the output side circuit. The resonant network is configured for alternatingly being charged from the input voltage or current and discharged through the rectification circuit by a first controllable switch arrangement in accordance with a first switch control signal. A second controllable switch arrangement of the resonant DC-DC power converter is configured to select a first impedance characteristic of the resonant network in a first switch state and select a second impedance characteristic of the resonant network in a second switch state. An output voltage or current control circuit is configured to adjust the converter output voltage and/or current by activating and interrupting the first switch control signal in accordance with the switch state of the second controllable switch arrangement.


Patent
Technical University of Denmark | Date: 2017-02-08

The present invention relates to a rotor for a pyrolysis centrifuge reactor, said rotor comprising a rotor body having a longitudinal centre axis, and at least one pivotally mounted blade being adapted to pivot around a pivot axis under rotation of the rotor body around the longitudinal centre axis. Moreover, the present invention relates to a pyrolysis centrifuge reactor applying such a rotor.


Patent
Technical University of Denmark | Date: 2017-02-15

The invention relates to a VCSEL structure based on a novel grating reflector. The grating reflector (1) comprises a grating layer (20) with a contiguous core grating region having a grating structure, wherein an index of refraction of high-index sections (21) of the grating structure is at least 2.5, and wherein an index of refraction of low-index sections (22) of the grating structure is less than 2. The core grating region defines a projection in a direction normal to the grating layer. The grating reflector further comprises a cap layer (30) abutting the grating layer (20), and an index of refraction of the cap layer within the projection of the core grating region onto the cap layer is at least 2.5, and within the projection of the core grating region, the cap layer is abutted by a first solid dielectric low-index layer, an index of refraction of the first low-index layer or air being less than 2; and within the projection of the core grating region, the grating layer is also abutted by a second low-index layer and/or by air, an index of refraction of the second low-index layer or air being less than 2. The VCSEL structure furthermore comprises a first reflector and an active region for providing a cavity and amplification. The cap layer (30) may comprise an active layer (32) between cladding layers (31,33) and electrical contacts (35,36) to provide a current through the active layer. Current confinement may be realized by low-index oxide regions (60).


The invention provides a method for the preparation of regioisomerically pure intermediates which are useful for the preparation of carboxy-fluorescein-type compounds. Such compounds have broad applications within bio-conjugation and/or fluorescent imaging.


A security scanning system (1) comprises a first stage module (3) having at least one X-ray source (6) and at least three first detectors (7) that are line-shaped and arranged in mutually different orientations and have at least dual energy resolution. A group of carry-on items (4) on a carrier are scanned simultaneously in the first stage module solely by transmission contrast radiography generating projections of two-dimensional image data. A processing device (9) reconstructs a 3D representation of the carry-on items and analyzes the 3D representation to determine whether further scanning is required.


Patent
Technical University of Denmark | Date: 2017-01-18

The present invention relates to a method for minimizing noise in a laser system, the laser system having two, or more, separate contacts for independently controlling currents to different sections of a diode laser; the method comprising the following steps:- determining noise in an emission of the laser system;- comparing the noise to a threshold value;- if the noise is above the threshold value, adjusting a current supplied to a first contact of said two or more separate contacts until the noise is below the threshold value,- if the noise is above the threshold value and the current supplied to said first contact is at a lowest current threshold level, adjusting the current supplied to a second contact of the two or more separate contacts.


Patent
Technical University of Denmark | Date: 2017-02-15

The invention relates to a guide blade (1) for an overflow structure (100) to be placed on a vessel, the guide blade comprising a primary contact surface (4) for guiding a stream of a water mixture into an overflow structure and a secondary contact surface (5) being a backside of the primary contact surface (4), the primary contact surface having an edge (2) configured for abutting an overflow structure (100) and at least one free edge, wherein the guide blade is configured for being attachable to a unit to be arrange on or in an inlet (109) of an overflow structure or directly on or in an inlet (109) of an overflow structure by means of one or more fastening elements or by welding. The invention further relates to an overflow system comprising one or more guide blades and an overflow structure. The invention further relates to a method of guiding a stream of a watery mixture approaching and/or entering an overflow structure by means of one or more guide blades.


A security scanning system (1) comprises a first stage module (3) and a second stage module (11). In the second stage, a group of carry-on items (4) determined in the first stage to have at least one local area (27) requiring further scanning is further scanned. The group of carry-on items and a X-ray source and a focusing device are mutually positioned so that a measuring position (25) is in line with the local area requiring further scanning, and the X-ray source emits photons in a polychromatic X-ray beam, which photons are focussed towards the measuring position by the focusing device (24), and at least one second detector (22) detects diffracted X-rays from the local area.


Marvig R.L.,Technical University of Denmark
Nature genetics | Year: 2015

Little is known about how within-host evolution compares between genotypically different strains of the same pathogenic species. We sequenced the whole genomes of 474 longitudinally collected clinical isolates of Pseudomonas aeruginosa sampled from 34 children and young individuals with cystic fibrosis. Our analysis of 36 P. aeruginosa lineages identified convergent molecular evolution in 52 genes. This list of genes suggests a role in host adaptation for remodeling of regulatory networks and central metabolism, acquisition of antibiotic resistance and loss of extracellular virulence factors. Furthermore, we find an ordered succession of mutations in key regulatory networks. Accordingly, mutations in downstream transcriptional regulators were contingent upon mutations in upstream regulators, suggesting that remodeling of regulatory networks might be important in adaptation. The characterization of genes involved in host adaptation may help in predicting bacterial evolution in patients with cystic fibrosis and in the design of future intervention strategies.


Kepp K.P.,Technical University of Denmark
Chemical Reviews | Year: 2012

A study was conducted to investigate the bioinorganic chemistry of Alzheimer's disease (AD). The two main histopathological criteria for AD were observations of extracellular deposits of fibrillar peptides, called senile plaques and of widespread intraneuronal fibrillar tangles. The senile plaques were formed from ̃40-residue fragments known as β-amyloids (Aβ), of the transmembrane amyloid precursor protein (APP) found in the membranes of cells and organelles such as mitochondria. The neurofibrillar tangles consisted of twisted strands of hyperphosphorylated tau protein, which was important for the structural integrity of microtubules, structural tubulin polymers of the cytoskeleton of the neurons, and were commonly observed upon neurodegeneration. The amyloid cascade hypothesis stated that impaired balance between Aβ production and clearance was the main cause of AD and that amyloids were the main neurotoxic substances in the disease.

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