Delft, Netherlands
Delft, Netherlands

Delft University of Technology ft]), also known as TU Delft, is the largest and oldest Dutch public technical university, located in Delft, Netherlands. With eight faculties and numerous research institutes it hosts over 19,000 students , more than 3,300 scientists and more than 2,200 people in the support and management staff.The university was established on January 8, 1842 by King William II of the Netherlands as a Royal Academy, with the main purpose of training civil servants for the Dutch East Indies. The school rapidly expanded its research and education curriculum, becoming first a Polytechnic School in 1864, Institute of Technology in 1905, gaining full university rights, and finally changing its name to Delft University of Technology in 1986.Dutch Nobel laureates Jacobus Henricus van 't Hoff, Heike Kamerlingh Onnes, and Simon van der Meer have been associated with TU Delft. TU Delft is a member of several university federations including the IDEA League, CESAER, UNITECH, and 3TU. Wikipedia.


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Patent
Technical University of Delft | Date: 2016-12-09

In a prior art reactor set up dense aggregates of microorganisms are formed, typically in or embedded in an extracellular matrix. Such may relate to granules, to sphere like entities having a higher viscosity than water, globules, a biofilm, etc. The dense aggregates comprise extracellular polymeric substances, or biopolymers, in particular linear polysaccharides. The present invention is in the field of extraction of a biopolymer from a granular sludge, a biopolymer obtained by such method, and a use of such method.


Disclosed is an ultrasonic transducer assembly comprising an ultrasonic transducer chip (100) having a main surface comprising a plurality of ultrasound transducer elements (112) and a plurality of first contacts (120) for connecting to said ultrasound transducer elements; a contact chip (400) having a further main surface comprising a plurality of second contacts (420); an backing member (300) comprising ultrasound absorbing and/or scattering bodies (310), said backing member comprising a first surface (302) on which the transducer chip is mounted and a second surface (306) on which the contact chip is mounted; and a flexible interconnect (200) extending over said backing member from the main surface to the further main surface, the flexible interconnect comprising a plurality of conductive tracks (210), each conductive track connecting one of said first contacts to a second contact. An ultrasound probe including such an assembly, an ultrasonic imaging system including such an ultrasound probes and manufacturing methods of such an assembly and probe are also disclosed.


A novel and useful mechanism for the skinning of 3D meshes with reference to a skeleton utilizing statistical weight optimization techniques. The mechanism of the present invention comprises (1) an efficient high quality linear blend skinning (LBS) technique based on a set of skeleton deformations sampled from the manipulation space; (2) a joint placement algorithm to optimize the input skeleton; and (3) a set of tools for a user to interactively control the skinning process. Statistical skinning weight maps are computed using an as-rigid-as-possible (ARAP) optimization. The method operates with a coarsely placed initial skeleton and optimizes joint placements to improve the skeletons alignment. Bones may also be parameterized incorporating twists, bends, stretches and spines. Several easy to use tools add additional constraints to resolve ambiguous situations when needed and interactive feedback is provided to aid users. Quality weight maps are generated for challenging deformations and various data types (e.g., triangle, tetrahedral meshes), including noisy, complex and topologically challenging examples (e.g., missing triangles, open boundaries, self-intersections, or wire edges).


Patent
Technical University of Delft | Date: 2015-02-25

The invention is directed to a method for recovering a lipid or hydrocarbon from a fermentation mixture, comprising the steps ofproviding a fermentation mixture wherein the lipid or hydrocarbon is produced by microbial fermentation in a fermentation vessel, which mixture comprises an aqueous phase and a liquid product phase, wherein the liquid product phase comprises the lipid or hydrocarbon; andfeeding at least part of the aqueous phase and part of the liquid product phase to a second vessel, thereby forming a second mixture; andpromoting phase-separation of the aqueous and product phase by injecting a gas into the second mixture, thereby separating the product phase from the aqueous phase; andcollecting the product phase comprising the lipid or hydrocarbon.


Patent
Technical University of Delft | Date: 2015-07-27

A novel and useful mechanism for the skinning of 3D meshes with reference to a skeleton utilizing statistical weight optimization techniques. The mechanism of the present invention comprises (1) an efficient high quality linear blend skinning (LB S) technique based on a set of skeleton deformations sampled from the manipulation space; (2) a joint placement algorithm to optimize the input skeleton; and (3) a set of tools for a user to interactively control the skinning process. Statistical skinning weight maps are computed using an as-rigid-as-possible (ARAP) optimization. The method operates with a coarsely placed initial skeleton and optimizes joint placements to improve the skeletons alignment. Bones may also be parameterized incorporating twists, bends, stretches and spines. Several easy to use tools add additional constraints to resolve ambiguous situations when needed and interactive feedback is provided to aid users. Quality weight maps are generated for challenging deformations and various data types (e.g., triangle, tetrahedral meshes), including noisy, complex and topologically challenging examples (e.g., missing triangles, open boundaries, self-intersections, or wire edges).


Patent
Technical University of Delft | Date: 2017-01-04

A method of maneuvering a smaller ship which is located alongside a larger ship whereas both ships initially have the same course and the same speed. The smaller ship includes a bow rudder or a Magnus rotor at a bow thereof and is maneuvered away from the larger ship by means of changing the orientation of its bow rudder or activating its Magnus rotor, respectively.


Straathof A.J.J.,Technical University of Delft
Chemical Reviews | Year: 2014

Transformation of biomass into commodity chemicals using enzymes or cells will be successful if the production process is more attractive than for alternative options to produce these chemicals. Sufficient second generation biomass should be available for a reasonable price, the price will not only be dictated by the biomass production but also by competitive uses of this biomass such as combustion for energy generation. All biomass components should be convertible into product, or otherwise into valuable coproduct. Too high bioreactor investments, due to high O2 requirements or too low productivities, should be avoided. Biochemical processes compete with chemical processes that aim at similar routes from biomass to product. The biochemical process should be more selective or should avoid production and isolation of intermediate chemicals. Scientific discoveries and method development have been very important to increase the rate of development of biochemical routes.


Sheldon R.A.,Technical University of Delft
Chemical Society Reviews | Year: 2012

In this tutorial review, the fundamental concepts underlying the principles of green and sustainable chemistry - atom and step economy and the E factor - are presented, within the general context of efficiency in organic synthesis. The importance of waste minimisation through the widespread application of catalysis in all its forms - homogeneous, heterogeneous, organocatalysis and biocatalysis - is discussed. These general principles are illustrated with simple practical examples, such as alcohol oxidation and carbonylation and the asymmetric reduction of ketones. The latter reaction is exemplified by a three enzyme process for the production of a key intermediate in the synthesis of the cholesterol lowering agent, atorvastatin. The immobilisation of enzymes as cross-linked enzyme aggregates (CLEAs) as a means of optimizing operational performance is presented. The use of immobilised enzymes in catalytic cascade processes is illustrated with a trienzymatic process for the conversion of benzaldehyde to (S)-mandelic acid using a combi-CLEA containing three enzymes. Finally, the transition from fossil-based chemicals manufacture to a more sustainable biomass-based production is discussed. © 2012 The Royal Society of Chemistry.


Sheldon R.A.,Technical University of Delft
Green Chemistry | Year: 2014

The various strategies for the valorisation of waste biomass to platform chemicals, and the underlying developments in chemical and biological catalysis which make this possible, are critically reviewed. The option involving the least changes to the status quo is the drop-in strategy of complete deoxygenation to petroleum hydrocarbons and further processing using existing technologies. The alternative, redox economic approach, is direct conversion of, for example, carbohydrates to oxygenates by fermentation or chemocatalytic processes. Examples of both approaches are described, e.g. fermentation of carbohydrates to produce hydrocarbons, lower alcohols, diols and carboxylic acids or acid catalyzed hydrolysis of hexoses to hydroxymethyl furfural (HMF) and subsequent conversion to levulinic acid (LA), γ-valerolactone (GVL) and furan dicarboxylic acid (FDCA). Three possible routes for producing a bio-based equivalent of the large volume polymer, polyethylene terephthalate (PET) are delineated. Valorisation of waste protein could, in the future, form an important source of amino acids, such as l-glutamic acid and l-lysine, as platform chemicals, which in turn can be converted to nitrogen containing commodity chemicals. Glycerol, the coproduct of biodiesel manufacture from triglycerides, is another waste stream for which valorisation to commodity chemicals, such as epichlorohydrin and acrolein, is an attractive option. © 2014 The Royal Society of Chemistry.


Hanefeld U.,Technical University of Delft
Chemical Society Reviews | Year: 2013

Hydroxynitrile lyases are a versatile group of enzymes that are applied both in the laboratory and on an industrial scale. What makes them particularly interesting is that to date five structurally unrelated categories of hydroxynitrile lyases have been discovered. Given their great importance they have often been immobilised utilising many different methodologies. Therefore the hydroxynitrile lyases are ideally suited to compare different immobilisation methods and their dependence on the structural features of the enzyme in question, since the activity is the same in all cases. This review examines all the different immobilisation methods applied to hydroxynitrile lyases and draws conclusions on the effect of the approach. © 2013 The Royal Society of Chemistry.

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