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Belo Horizonte, Brazil

Amr M.,Mansoura University | Volpe F.M.,Teaching and Research Management
Asian Journal of Psychiatry

Background: Anhedonia and impulsivity are prominent symptoms of many psychiatric disorders and may indicate worse prognosis, notably in schizophrenia and major depression. Despite the convergence of negative outcomes from both dimensions, the relationship between anhedonia and impulsivity in psychiatric disorders has been seldom directly assessed. The objective of the present study is to examine the correlations between anhedonia and impulsivity in three diagnostic groups: major depression, schizophrenia and schizoaffective disorder. Sampling and methods: 121 outpatients (Mansoura University Hospital, Egypt) with major depressive disorder (N= 29), schizophrenia (N= 59), and schizoaffective disorder (N= 33), were assessed and responded to the Beck Depression Inventory, Barrat's Impulsivity Scale-11, and Chapman's Social and Physical Anhedonia Scales. Results: Physical and social anhedonia scores were negatively correlated to impulsivity scores in major depression patients. Conversely, higher scores in physical and social anhedonia predicted higher impulsivity scores in schizophrenia. No correlations between impulsivity and anhedonia were evidenced among schizoaffectives. Conclusion: The relationship between self-reported physical and social anhedonia and impulsivity is diagnosis-specific. © 2013 Elsevier B.V. Source

Pereira A.B.,Veiga de Almeida University | de Melo Silva G.S.,Veiga de Almeida University | Assuncao A.R.M.,Hospital Universitario Pedro Ernesto | Atherino C.C.T.,Hospital Universitario Pedro Ernesto | And 2 more authors.
Brazilian Journal of Otorhinolaryngology

Introduction: Cervical vestibular evoked myogenic potential is a test used in neurotological examination. It verifies the integrity of vestibular function through a muscular response evoked by an acoustic stimulation which activates the saccular macula. Normal standards in adults have been established, however, there are few published data on the normal responses in children. Objective: To establish normal standards for vestibular myogenic responses in children without neurotological complaints. Methods: This study's design is a cohort with cross-sectional analysis. The sample consisted of 30 subjects, 15 females (50%) and 15 males (50%). Results: The age of the subjects ranged between 8 and 13 years, with a mean of 10.2 (± 1.7). P1 peak showed an average latency of 17.26 (± 1.78). ms and a mean amplitude of 49.34 (± 23.07). μV, and the N2 peak showed an average latency of 24.78 (± 2.18). ms and mean amplitude of 66.23 (± 36.18). μV. P1-N2 mean amplitude was 115.6 (± 55.7). μV. There were no statistically significant differences when comparing by gender or by laterality. Conclusion: We established normal values of cervical myogenic vestibular responses in children between 8 and 13 years without neurotological complaints. Introdução: Objetivo: Método: Resultados: Conclusão: © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Source

Galperim B.,Gastroenterology Service | Galperim B.,Federal University of Health Sciences, Porto Alegre | Mattos A.A.,Federal University of Health Sciences, Porto Alegre | Stein A.T.,Teaching and Research Management | And 6 more authors.
Brazilian Journal of Infectious Diseases

Background: Hepatitis C virus (HCV) infection is the most common cause of acute or chronic hepatitis in patients on hemodialysis (HD). The purpose of this study was to describe the prevalence of positive HCV RNA and investigate injection drug use as an emerging risk factor in patients with chronic renal disease on HD. Methods: This was a multicenter cross-sectional study with 325 patients with chronic renal disease on HD in the period between August 1, 2005 to August 30, 2006, receiving care at four institutions in the city of Porto Alegre, Southern Brazil. Epidemiological data were collected by means of a structured questionnaire. The following laboratory tests were performed: alanine aminotransferase (ALT), anti-hepatitis C virus antibodies (anti-HCV), and qualitative polymerase chain reaction (PCR). Results: Of 325 patients, 68 had positive HCV RNA results. The comparison between patients with positive and negative PCR results revealed significant differences in duration of HD (mean = 71 versus 52.4 months; p = 0.02); previous blood transfusion (92% versus 72%; p < 0.01); injection drug use (13% versus 0.7%; p < 0.01); anti-HCV positivity at start of HD therapy (60% versus 4%; p < 0.01); and mean ALT value (39 versus 26.5; p < 0.01). Logistic regression analysis showed a positive HCV RNA independently associated to being on HD for more than five years [OR: 2.1 (95% CI 1.2 - 3.8)]; previous blood transfusion [OR: 3.7 (95% CI 1.4 - 9.5)]; and injection drug use [OR: 22.6 (95% CI 4.2 - 119.6)]. Conclusion: Injection drug use was an independent risk factor for HCV infection among chronic renal disease patients on HD. ©Elsevier Editora Ltda. Source

Pereira A.B.,Teaching and Research Management | Almeida L.A.F.,Teaching and Research Management | Pereira N.G.,Teaching and Research Management | De Menezes P.A.F.,Teaching and Research Management | And 2 more authors.
Chronobiology International

Vertigo and dizziness are among the most common medical complaints in the emergency room, and are associated with a considerable personal and health care burden. Scarce and conflicting reports indicate those symptoms may present a seasonal distribution. This study aimed at investigating the existence of a seasonal distribution of vertigo/dizziness in a tropical region, and the correlations of these findings with climatic variables. The charts of all patients consecutively admitted between 2009 and 2012 in the emergency room of a Brazilian general hospital were reviewed. A total of 4920 cases containing these terms were sorted from a sample of 276076 emergency records. Seasonality was assessed using Cosinor Analysis. Pearson's correlations were performed between the incidence of consultations, considering separately dizziness and vertigo and each of the predictor climatic variables of that index month. Significant seasonal patterns were observed for dizziness and vertigo in the emergency room. Vertigo was more frequent in late winter-spring, negatively correlating to humidity (r=-0.374; p=0.013) and rainfall (r=-0.334; p=0.020). Dizziness peaked on summer months, and positively correlated to average temperatures (r=0.520; p<0.001) and rainfall (r=0.297; p=0.040), but negatively to atmospheric pressure (r=-0.424; p=0.003). The different seasonal patterns evidenced for dizziness and vertigo indicate possible distinct underlying mechanisms of how seasons may influence the occurrence of those symptoms. © 2015 Informa Healthcare USA, Inc. Source

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