Tateyama Machine Co.

Toyama-shi, Japan

Tateyama Machine Co.

Toyama-shi, Japan
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Nabesawa H.,Chiba University | Nabesawa H.,Japan Central Research Institute of Electric Power Industry | Hiruma T.,Chiba University | Hitobo T.,Tateyama Machine Co. | And 5 more authors.
AIP Advances | Year: 2013

In this study, we have proposed a low-pressure reactive ion etching of bulk polymer materials with a gas mixture of CF4 and O2, and have achieved precise fabrication of poly(methyl methacrylate) (PMMA) and perfluoroalkoxy (PFA) bulk polymer plates with high-aspect-ratio and narrow gap array structures, such as, pillar, frustum, or cone, on a nano/micro scale. The effects of the etching conditions on the shape and size of each pillar were evaluated by changing etching duration and the size/material of etching mask. The fabricated PMMA array structures indicate possibilities of optical waveguide and nanofiber array. PFA cone array structures showed super-hydrophobicity without any chemical treatments. Also, polystyrene-coated silica spheres were used as an etching mask for the pillar array structure formation to control the gap between pillars. © 2013 © 2013 Author(s).


Asaji T.,National Institute of Technology, Toyama College | Nakamura T.,Japan National Institute of Advanced Industrial Science and Technology | Furuse M.,Japan National Institute of Advanced Industrial Science and Technology | Hitobo T.,Tateyama Machine Co. | And 3 more authors.
Review of Scientific Instruments | Year: 2016

A new electron cyclotron resonance ion source has been constructed at Oshima College with a 2.45 GHz magnetron microwave source and permanent magnets employed as the main components. In addition, a solid-state power amplifier with a frequency range of 2.5-6.0 GHz was installed to study two-frequency plasma heating. Three solenoid coils were set up for adjusting the axial magnetic fields. Argon plasma generation and ion beam production have been conducted during the first year of operation. Ion current densities in the ECR plasma were measured using a biased disk. For 2.45 and 4.65 GHz two-frequency plasma heating, the ion density was approximately 1.5 times higher than that of 2.45 GHz single-frequency heating. © 2015 AIP Publishing LLC.


Uchida T.,Toyo University | Minezaki H.,Toyo University | Tanaka K.,Tateyama Machine Co. | Muramatsu M.,Japan National Institute of Radiological Sciences | And 5 more authors.
Review of Scientific Instruments | Year: 2010

We developed an electron cyclotron resonance ion source (ECRIS) for new materials production on nanoscale. Our main target is the endohedral fullerenes, which have potential in medical care, biotechnology, and nanotechnology. In particular, iron-encapsulated fullerene can be applied as a contrast material for magnetic resonance imaging or microwave heat therapy. Thus, our new ECRIS is named the Bio-Nano ECRIS. In this article, the recent progress of the development of the Bio-Nano ECRIS is reported: (i) iron ion beam production using induction heating oven and (ii) optimization of singly charged C60 ion beam production. © 2010 American Institute of Physics.


Rehman M.U.,University of Toyama | Jawaid P.,University of Toyama | Uchiyama H.,Tateyama Machine Co. | Kondo T.,University of Toyama
Archives of Biochemistry and Biophysics | Year: 2016

Plasma medicine is increasingly recognized interdisciplinary field combining engineering, physics, biochemistry and life sciences. Plasma is classified into two categories based on the temperature applied, namely "thermal" and "non-thermal" (i.e., cold atmospheric plasma). Non-thermal or cold atmospheric plasma (CAP) is produced by applying high voltage electric field at low pressures and power. The chemical effects of cold atmospheric plasma in aqueous solution are attributed to high voltage discharge and gas flow, which is transported rapidly on the liquid surface. The argon-cold atmospheric plasma (Ar-CAP) induces efficient reactive oxygen species (ROS) in aqueous solutions without thermal decomposition. Their formation has been confirmed by electron paramagnetic resonance (EPR) spin trapping, which is reviewed here. The similarities and differences between the plasma chemistry, sonochemistry, and radiation chemistry are explained. Further, the evidence for free radical formation in the liquid phase and their role in the biological effects induced by cold atmospheric plasma, ultrasound and ionizing radiation are discussed. © 2016.


PubMed | Nagoya University, University of Toyama and Tateyama Machine Co.
Type: Comparative Study | Journal: PloS one | Year: 2015

Electron paramagnetic resonance (EPR)-spin trapping and flow cytometry were used to identify free radicals generated using argon-cold atmospheric plasma (Ar-CAP) in aqueous solutions and intracellularly in comparison with those generated by X-irradiation. Ar-CAP was generated using a high-voltage power supply unit with low-frequency excitation. The characteristics of Ar-CAP were estimated by vacuum UV absorption and emission spectra measurements. Hydroxyl (OH) radicals and hydrogen (H) atoms in aqueous solutions were identified with the spin traps 5,5-dimethyl-1-pyrroline N-oxide (DMPO), 3,3,5,5-tetramethyl-1-pyrroline-N-oxide (M4PO), and phenyl N-t-butylnitrone (PBN). The occurrence of Ar-CAP-induced pyrolysis was evaluated using the spin trap 3,5-dibromo-4-nitrosobenzene sulfonate (DBNBS) in aqueous solutions of DNA constituents, sodium acetate, and L-alanine. Human lymphoma U937 cells were used to study intracellular oxidative stress using five fluorescent probes with different affinities to a number of reactive species. The analysis and quantification of EPR spectra revealed the formation of enormous amounts of OH radicals using Ar-CAP compared with that by X-irradiation. Very small amounts of H atoms were detected whereas nitric oxide was not found. The formation of OH radicals depended on the type of rare gas used and the yield correlated inversely with ionization energy in the order of krypton > argon = neon > helium. No pyrolysis radicals were detected in aqueous solutions exposed to Ar-CAP. Intracellularly, OH, H2O2, which is the recombination product of OH, and OCl- were the most likely formed reactive oxygen species after exposure to Ar-CAP. Intracellularly, there was no practical evidence for the formation of NO whereas very small amounts of superoxides were formed. Despite the superiority of Ar-CAP in forming OH radicals, the exposure to X-rays proved more lethal. The mechanism of free radical formation in aqueous solutions and an intracellular milieu is discussed.


PubMed | Nagoya University, University of Toyama and Tateyama Machine Co.
Type: Journal Article | Journal: International journal of molecular medicine | Year: 2016

Cold atmospheric pressure plasma(CAP) is known as a source of biologically active agents, such as reactive oxygen species(ROS) and reactive nitrogen species(RNS). In the present study, we examined the effects of nitrogen(N2) on the apoptosis of and changes in gene expression in human lymphomaU937 cells exposed to argon(Ar)-CAP. Enormous amounts of hydroxyl(OH) radicals in aqueous solution were produced using ArCAP generated using a 20kHz low frequency at 18kV with a flow rate of 2l/min. The increase in the levels of OHradicals was significantly attenuated by the addition of N2 to Argas. On the other hand, the level of total nitrate/nitrite in the supernatant was significantly elevated in the Ar+N2-CAPexposed U937 cells. When the cells were exposed to ArCAP, a significant increase in apoptosis was observed, whereas apoptosis was markedly decreased in the cells exposed to Ar+N2-CAP. Microarray and pathway analyses revealed that a newly identified gene network containing a number of heat shock proteins(HSPs), anti-apoptotic genes, was mainly associated with the biological function of the prevention of apoptosis. Quantitative PCR revealed that the expression levels of HSPs were significantly elevated in the cells exposed to Ar+N2-CAP than those exposed to ArCAP. These results indicate that N2gas in ArCAP modifies the ratio of ROS to RNS, and suppresses the apoptosis induced by ArCAP. The modulation of gaseous conditions in CAP may thus prove to be useful for future clinical applications, such as for switching from a sterilizing mode to cytocidal effect for cancer cells.


PubMed | University of Toyama and Tateyama Machine Co.
Type: | Journal: Archives of biochemistry and biophysics | Year: 2016

Plasma medicine is increasingly recognized interdisciplinary field combining engineering, physics, biochemistry and life sciences. Plasma is classified into two categories based on the temperature applied, namely thermal and non-thermal (i.e., cold atmospheric plasma). Non-thermal or cold atmospheric plasma (CAP) is produced by applying high voltage electric field at low pressures and power. The chemical effects of cold atmospheric plasma in aqueous solution are attributed to high voltage discharge and gas flow, which is transported rapidly on the liquid surface. The argon-cold atmospheric plasma (Ar-CAP) induces efficient reactive oxygen species (ROS) in aqueous solutions without thermal decomposition. Their formation has been confirmed by electron paramagnetic resonance (EPR) spin trapping, which is reviewed here. The similarities and differences between the plasma chemistry, sonochemistry, and radiation chemistry are explained. Further, the evidence for free radical formation in the liquid phase and their role in the biological effects induced by cold atmospheric plasma, ultrasound and ionizing radiation are discussed.


Yamada S.,Niigata University | Hitobo T.,Tateyama Machine Co. | Sohgawa M.,Niigata University | Abe T.,Niigata University
IEEJ Transactions on Sensors and Micromachines | Year: 2014

In this paper, we report a micromachining of titanium using a desktop DRIE and fabrication of microstructure. We found out high speed exhaust characteristic is indispensable in the etching of titanium, and the etching rate more than 0.2 μm/min (a maximum rate is 0.4 μm/min) was provided in a small amount of etching gas (SF6). As the demonstration of the method, we fabricated microneedles imitating mosquito's proboscis. We revealed that it is available for fabricating precision microstructure. Titanium has excellent mechanical property and corrosion resistance, and it is expected to be used as a material for MEMS. In this method, it is expected to apply to fabricate the three-dimensional structures. © 2014 The Institute of Electrical Engineers of Japan.


Kamikura S.,Toyo University | Uchida T.,Toyo University | Naka K.,Toyo University | Asaji T.,Tateyama Machine Co. | And 2 more authors.
Diamond and Related Materials | Year: 2011

We demonstrate that the Co nanoparticles prepared by vacuum deposition on a surface-active liquid can be used as catalysts of single-walled carbon nanotube (SWCNT) growth using alcohol catalytic chemical vapor deposition method. These Co nanoparticles are embedded in the y-type zeolite powder. The Co nanoparticles used in this study is the highly efficient catalysts for CNT growth, which is comparable to the commonly-used Co-Fe binary metal catalysts embedded in the y-type zeolite. The preparation method of the metal nanoparticles used in this study is very simple. Thus, such metal nanoparticles might be promising as catalysts of CNT growth. © 2011 Elsevier B.V. All rights reserved.


PubMed | Tateyama Machine Co.
Type: Journal Article | Journal: The Review of scientific instruments | Year: 2012

Fullerene plasmas generated by pulse-modulated microwaves have been investigated under typical conditions at the Bio-Nano electron cyclotron resonance ion source. The effect of the pulse modulation is distinct from that of simply structured gases, and then the density of the fullerene plasmas increased as decreasing the duty ratio. The density for a pulse width of 10 s at the period of 100 s is 1.34 times higher than that for CW mode. We have studied the responses of fullerene and argon plasmas to pulsed microwaves. After the turnoff of microwave power, fullerene plasmas lasted 30 times longer than argon plasmas.

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