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Sun X.-G.,Tang County of Hebei Provincial Peoples Hospital | Gao H.-B.,No. 401 Hospital of China Nuclear Industry | Wang B.,Tang County of Hebei Provincial Peoples Hospital | Wang H.-T.,Tang County of Hebei Provincial Peoples Hospital | And 2 more authors.
Journal of Dalian Medical University | Year: 2014

Objective: To study the use of different recovery fluid in patients with uncontrolled hemorrhagic shock resuscitation fluid plasma TNF-α, the influence of IL-2, so as to provide basis for uncontrolled hemorrhagic shock were treated by liquid recovery way. Methods: Forty patients with uncontrolled hemorrhagic shock were selected between April 2010 to August 2010, they were randomly divided into observation group and control group, observation group using restrictive liquidrecovery, and control group using conventional liquid recovery before bleeding control, serum TNF-α, IL-2 levels of change and recovery liquid intake during recovery in two groups were observed. Results: The average recovery liquid of patients in observation group was (1 946 ± 349) mL input variables significantly lower than control group, (3 522 ± 540) mL, with statistical difference (P < 0.05). Two groups patients serum TNF-α level 60 min after the recovery are higher than before the recovery level, with statistical difference (P < 0.05), the observation group of patients with serum TNF-α level 60 min after recovery level were significantly lower than the control group, with statistical difference (P<0.05). The patient's level of serum IL-2 of two group were higher than normal amount of 60 min after the recovery and the level before recovery, with statistical difference (P < 0.05), the observation group of patients with serum level of IL-2 in the 60 min after recovery levels were significantly lower than the control group, with statistical difference (P < 0.05). Conclusion: limited fluid resuscitation can significantly reduce uncontrolled hemorrhagic shock in patients with blood loss, stable flow mechanics, guarantee the important organs such as heart, brain, kidney blood perfusion, reduce the excessive blood dilution and acidosis, reduce serum TNF-α and IL-2 levels, improve the prognosis.

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