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Chandra S.J.,Tamil Nadu Government Dental College
Journal International Medical Sciences Academy | Year: 2010

We are reporting cases of submandibular modalities of conventional radiography ultrasonogram (USG), Computed Tomography (C.T. scan) subsequent treatment approach. Source

Jayanthi R.,Stanley Medical College | Nasser K.S.G.A.,Tamil Nadu Government Dental College | Monica K.,Stanley Medical College
Journal of Association of Physicians of India | Year: 2016

Lidocaine Hydrochloride is an amide ester, which is widely used local anesthetic agent that is well tolerated but what is less known is the occurrence of systemic toxicity which manifests in the central nervous and cardiovascular systems. We report here 3 cases of Lidocaine associated Seizures. © 2016, Journal of Association of Physicians of India. All Rights reserved. Source

Padma Priya S.,Ajman University for Science and Technology | Higuchi A.,National Central University | Higuchi A.,King Saud University | Higuchi A.,National Health Research Institute | And 10 more authors.
Laboratory Investigation | Year: 2015

The ultimate goal of dental stem cell research is to construct a bioengineered tooth. Tooth formation occurs based on the well-organized reciprocal interaction of epithelial and mesenchymal cells. The dental mesenchymal stem cells are the best explored, but because the human odontogenic epithelium is lost after the completion of enamel formation, studies on these cells are scarce. The successful creation of a bioengineered tooth is achievable only when the odontogenic epithelium is reconstructed to produce a replica of natural enamel. This article discusses the untapped sources of odontogenic epithelial stem cells in humans, such as those present in the active dental lamina in postnatal life, in remnants of dental lamina (the gubernaculum cord), in the epithelial cell rests of Malassez, and in reduced enamel epithelium. The possible uses of these stem cells in regenerative medicine, not just for enamel formation, are discussed. © 2015 USCAP, Inc All rights reserved. Source

Gunasekar C.,Sanjay Gandhi Post Graduate Institute of Medical Sciences | Nasser K.S.G.A.,Tamil Nadu Government Dental College | Sabarigirinathan C.,Tamil Nadu Government Dental College | Kumar K.R.,Tamil Nadu Government Dental College
Indian Journal of Dental Research | Year: 2013

Restoration of near normal functions in patients who have been treated with hemimaxillectomy is generally difficult, in view of the restriction in mouth opening following healing of large surgical wound. Further, the extent and nature of the surgical defect differ from patient to patient. Thus, design of an obturator needs to be patient oriented. In this report, we describe a novel snap-on attachment with O-ring in a conventional two piece hollow bulb obturator for a 70-year-old male treated for carcinoma of the left maxilla and sinus. Source

Selvam N.,Tamil Nadu Government Dental College | Sadaksharam J.,Tamil Nadu Government Dental College | Singaravelu G.,Anna University | Ramu R.,Anna University
Journal of Cancer Research and Therapeutics | Year: 2015

Aim of the Study: Oral leukoplakia (OL) is the most common potentially malignant disorder that may transform into oral carcinoma. By treating leukoplakia in its incipient stage, the risk of occurrence of oral carcinoma can be prevented. In this aspect, photodynamic therapy (PDT) can serve as a useful treatment modality. The aim of the study is to treat patients with OL using PDT in which 5-aminolevulinic acid (ALA) is used as a photosensitizer. Materials and Methods: Five patients with OL were included in the study. They were treated with 10% ALA mediated PDT (light source: Xenon lamp, power: 0.1 W, wavelength: 630 ± 5 nm, total dose: 100 J/cm 2 per session) for 6-8 sessions. Follow-up was done for a period of 1 year. Results: One month (4 weeks) after ALA-PDT, the response was evaluated based on clinical examination. It was as follows: Complete response: Two patients; partial response: Two patients; and no response: One patient. There was no recurrence in any of the cases. Conclusion: There was satisfactory reduction in the size of the OL lesion without any side-effects. Thus, ALA mediated PDT seems to be a promising alternative for the treatment of OL. Source

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