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Dushanbe, Tajikistan

Tajik State Medical University is a public university in Tajikistan. Established in 1939, it is located in Dushanbe and named after Avicenna. It is managed by the Ministry of Health. During its membership in the Soviet Union, it was the second best university in the USSR. Wikipedia.


Gafurov B.A.,Tajik State Medical University | Mirsaidov I.U.,Academy of Sciences of Tajikistan | Nasrulloeva D.K.,Academy of Sciences of Tajikistan | Badalov A.,Osimi Tajik Technical University
Russian Journal of Physical Chemistry A | Year: 2013

Lanthanide borohydride tris-tetrahydrofuranates (Ln(BH4) ·3THF, where THF is tetrahydrofuran and Ln is La, Nd, Sm, Gd, Er, Yb, and Lu) is synthesized via the exchange reaction of lanthanide(III) chloride and sodium borohydride in THF. It is found that synthesis proceeds according to a stepwise mechanism and the product of the reaction (lanthanide borohydride) initiates the process. The two-step character of the desolvation of Ln(BH 4)3·3THF under steady-state conditions in the temperature range of 300 to 400 K is determined through X-ray phase and chemical analyses, tensiometry, and gas volumetry. It is established that one mole and then two moles of THF are removed from the initial sample at the first and second steps, respectively. Equations for barograms are obtained and the thermodynamic characteristics of desolvation of Ln(BH4) 3·3THF under study are calculated. Gibbs energy values of the stages of process are determined semi-empirically. The law of its change for the entire series of Ln(BH4)3·3THF is determined with the emergence of the tetrad effect. © 2013 Pleiades Publishing, Ltd. Source


Gaibov A.D.,Tajik State Medical University
Novosti Khirurgii | Year: 2015

Objectives. To evaluate the results of complex diagnostics and surgical treatment of patients with pheochromocytoma. Methods. Treatment results of 25 patients with pheochromocytoma (PCC) have been analyzed (15 (60%) females and 10 (40%) males). The average age of patients was 35,9±4,2 years. Average duration on the disease was 4,6±1,7 years. Diagnosis was confirmed by ultrasonography (US), computerized tomography (CT) and determination of metanephrines (MN) and vanillylmandelic acid (VMA) levels. Depending on the preoperative tactics all patients were divided into 2 groups. ?-blockers of short-acting (phentolamine) were used to the patients of the first group (n=8) only during the operation. ?-blockers (doxazosin) were administered to the patiens of the second group (n=17) in the preoperative period. Results. In all cases a reliable increase of MN and VMA levels was registered. No difference was found in studying MN excretion level depending on the tumor size and disease duration. Sensitivity of US and CT in PCC diagnostics made up 92% and 100%, and specificity 52% and 91,3%, respectively. In the 1st group 2 (25%) patients died due to the development of "uncontrolled hemodynamics" syndrome. There was no lethal outcome in the 2nd group (?<0,05). Complications were observed in 5 (21,7%) patients during the operation (n=2) and in the early postoperative period (n=3). There was 1 (4,3%) lethal outcome after adrenalectomy. In the long-term period (1-8 yrs) good results were obtained in 21 (91,3%) operated patients and satisfactory - in 1 (4,3%). Conclusion. The use of minimally invasive techniques in the treatment of pheochromocytoma can help reduce the incidence of postoperative complications and duration of hospitalization. In all cases the preoperative preparation should be carried out with the use of α-blockers. The patients are required clinical medical examination and proper conduction of hormone replacement therapy to prevent and treat adrenal insufficiency. Source


Tajik State Medical University | Entity website

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Versporten A.,University of Antwerp | Bolokhovets G.,Health Technologies and Pharmaceuticals | Abilova V.,Analytical Expertise Center for Medicines | Pyshnik G.,Ministry of Health | And 13 more authors.
The Lancet Infectious Diseases | Year: 2014

Background: There are no reliable data on antibiotic use in non-European Union (EU) southern and eastern European countries and newly independent states. We aimed to collect valid, representative, comparable data on systemic antimicrobial use in these non-EU countries of the WHO European region. Methods: Validated 2011 total national wholesale antibiotic-use data of six southern and eastern European countries and regions and seven newly independent states were analysed in accordance with the WHO anatomical therapeutic chemical (ATC)/defined daily doses (DDD) method and expressed in DDD/1000 inhabitants per day (DID). Findings: Total (outpatients and hospital care) antibiotic use ranged from 15·3 DID for Armenia to 42·3 DID for Turkey. Co-amoxiclav was mainly used in Georgia (42·9% of total antibiotic use) and Turkey (30·7%). Newly independent states used substantial quantities of ampicillin and amoxicillin (up to 55·9% of total antibiotic use in Azerbaijan). Montenegro and Serbia were the highest consumers of macrolides (15·8% and 19·5% of total antibiotic use, respectively), mainly azithromycin. Parenteral antibiotic treatment is common practice: 46·4% of total antibiotic use in Azerbaijan (mainly ampicillin; 5·3 DID) and 31·1% of total antibiotic use in Tajikistan (mainly ceftriaxone 4·7 DID). Interpretation: This study provides publicly available total antibiotic-use data for 13 non-EU countries and areas of the WHO European region. These data will raise awareness of inappropriate antibiotic use and stimulate policy makers to develop action plans. The established surveillance system provides a method to develop quality indicators of antibiotic use and to assess the effect of policy and regulatory actions. Funding: Netherlands Ministry of Health, Welfare, and Sport, and EU. © 2014 World Health Organization. Published by Elsevier Ltd/Inc/BV. All rights reserved. Source


Karim-Zade K.,Tajik State Medical University | Leak C.,London School of Hygiene and Tropical Medicine | Karim-Zade B.,Tajik State Medical University
Ophthalmic Epidemiology | Year: 2016

Purpose: Pediatric eye injury (PEI) is the leading cause of preventable monocular vision loss in children, with an estimated prevalence of 5.7 million cases. Epidemiological information on PEI is rare, skewed towards high-income countries, and commonly overlooked by non-governmental ophthalmological organizations. This study aims to quantitatively and qualitatively determine incidence of PEI in the Republic of Tajikistan. Methods: Data were collected from all pediatric eye injury records (N = 454) admitted to three pediatric ophthalmology hospitals in two regions of Tajikistan between 2010 and 2012. Results: A review of the records revealed a cumulative annual incidence of 12.8 PEI cases/100,000, with marked inter- and intra-regional differences. Mean age was 7.0 years (95% confidence interval, CI, 6.7–7.4), and male to female ratio was 2.5:1. PEI occurred predominantly outdoors (63%), in rural settings (76%) during unsupervised play, and typically resulted from the eye being hit (53%) by a pointed object (51%), resulting in an open-globe injury (56%). Median time-to-presentation was 24 hours (range 9.6 hours–10 days) and median duration of hospitalization was 15 days (range 2–29 days). Of the 454 cases, 111 (25%) resulted in a blind eye, 62 (14%) in severe visual impairment, and 45 (10%) in moderate visual impairment. Conclusions: PEI is a major cause of pediatric monocular visual impairment in Tajikistan, with a high rural incidence of severe blinding injuries. Potential risks and outcomes relate to Tajikistan’s cultural, historical, and physical settings. We anticipate that the information provided by this study will facilitate development of culturally derived strategies to reduce PEI in Tajikistan. © 2016 Taylor & Francis Source

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