Rao T.P.,Taiyo Kagaku Co.
Physiology and Behavior | Year: 2016
Appetite control and reduction of additional calorie intake may be a logical approach for proper weight management. Viscous dietary fibers are effective in appetite control but difficult to apply in normal serving sizes in foods and nutritional supplements due to their viscosity and required high doses. Guar fiber popularly known as partially hydrolyzed guar gum (PHGG) is near non-viscous soluble fiber that has been proven effective in providing many physiological benefits. Guar fiber has also been identified as potential natural food and nutritional supplement ingredient for appetite control. The aim of this review is to summarize all the clinical studies pertinent to its effects on appetite control in normal subjects and postulate the mechanism of action. Guar fiber exhibited appetite control via delaying the colonic transit time of digested food, stimulation of satiety hormone cholecystokinin (CCK) and induction of prolonged perception of post-meal satiation and satiety effects. Regular intake of guar fiber at a dose of 2 g/serving provided significant sustained post-meal satiation effects and minimized the inter-meal calorie intake by about 20% in normal subjects. The intake of guar fiber alone at a dose > 5 g/serving or its combination with protein (2.6 g guar fiber + 8 g protein/serving) showed acute satiety effects in normal subjects. Guar fiber containing >. 85% dietary fiber, with clear solubility and negligible taste impact, may be an ideal natural dietary fiber for use in food and supplement applications at low dosage levels for appetite control. © 2016 Elsevier Inc.. Source
Orita T.,Mie University |
Orita T.,Taiyo Kagaku Co. |
Kato K.,Japan National Institute of Advanced Industrial Science and Technology |
Tomita M.,Mie University
Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan | Year: 2011
Mesoporous silicas (MPS) are potential materials for adsorption of antibodies on their surface as they have the following features: a) an ordered pore network and b) a high surface area. These unique features make MPS an excellent candidate as an immobilizing carrier for immunoassays. We present here the relationship between antibody molecules and pore diameters of various MPS; moreover, the thermal stability and the organic solvent stability of antibodies immobilized on MPS are evaluated. From six MPS, the entire amount of antibodies (44 μg) was adsorbed on four MPS (3 mg; pore sizes: 3.4, 11.0, 15.0, and 23.1 nm) but not on MPS with 5.8 and 8.1nm pores. However, the binding activities of antibodies to antigens were high only on MPS with 3.4 and 5.8nm pores. Regarding the thermal stability of antibodies immobilized on MPS, the antibody immobilized on 23.1nm pore MPS kept about 30% activity even after 3 h at 80°C, but that on 3.4nm pore MPS was markedly decreased (<10% activity) after that time. These results indicated that the Fab fragment, which is an antigen binding site of the antibody, was incorporated inside larger pores but remained outside smaller pores. © 2011 The Ceramic Society of Japan. Source
Orita T.,Mie University |
Orita T.,Taiyo Kagaku Co. |
Tomita M.,Mie University |
Kato K.,Japan National Institute of Advanced Industrial Science and Technology
Colloids and Surfaces B: Biointerfaces | Year: 2011
Regenerative medicine for repairing damaged body tissues has recently become critically important. Cell culture scaffolds are required for the control of cell attachment, proliferation, and differentiation in in vitro cell cultures. A new strategy to control cell adhesion, morphology, and proliferation was developed by culturing mouse osteoblast-like MC3T3-E1 cells on novel cell culture scaffolds fabricated using ordered nanometer-sized pores (100, 300, 500, and 1000. nm).Results of this study indicate that after 72. h of incubation, the number of cells cultured on a silica film with a pore size of 1000. nm was similar to or slightly lower than that cultured on a non-porous control silica film. Films with 100-500. nm pore sizes, however, resulted in the cell growth inhibition. Morphology of the cultured cells revealed increased elongation and the formation of actin stress fibers was virtually absent on macroporous silica films with 100-500. nm pore size. Vinculin molecules expressed in cells cultured on the non-porous silica films showed many clear focal adhesions, whereas focal contacts were insufficiently formed in cells cultured on macroporous films. The influence of hydroxyapatite (HAp) and alumina scaffolds on the behavior of MC3T3-E1 cells was also evaluated. The proliferation rate of MC3T3-E1 cells cultured on HAp films with 1000. nm pore size was increased to approximately 20% above than that obtained of cells cultured on non-porous HAp films. These results demonstrate that the pore size and constituents of films play a role in controlling the morphology and proliferation rate of MC3T3-E1cells. © 2011 Elsevier B.V. Source
Taiyokagaku Co. | Date: 2013-01-28
An object of the present invention is to provide a beverage packed in a sealed container, which can suppress occurrence of precipitation for a long period and retain high flavor. The above-described problem can be overcome by containing (1) theanine ranging from 100 mg to 1000 mg and (2) quinic acid ranging from 30 mg to 300 mg per 500 ml beverage.
City Of Nagoya and Taiyo Kagaku Co. | Date: 2011-08-18
An impact resistance enhancing agent for a polylactic acid-based resin, containing a polyglycerol fatty acid ester made from a fatty acid containing at least one member selected from the group consisting of caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, stearic acid, and oleic acid, in an amount of 80% by mass or more of the constituting fatty acids, and a polyglycerol having an average degree of polymerization of from 2 to 40. The polylactic acid-based resin composition containing an impact resistance enhancing agent for a polylactic acid-based resin of the present invention has excellent impact resistance properties, so that the resin composition can be suitably used in, for example, agricultural materials, food wrapping materials, and other wrapping materials, and the like.