Sakai, Japan

Taisei Gakuin University is a private university in Sakai, Osaka, Japan. The predecessor of the school was founded in 1916, and it was chartered as a junior college in 1987. The school became a four-year college in 1998 and adopted the present name in 2003. Wikipedia.


Time filter

Source Type

Tamaki J.,Kinki University | Iki M.,Kinki University | Fujita Y.,Kinki University | Kouda K.,Kinki University | And 7 more authors.
Osteoporosis International | Year: 2011

Summary: Our cross-sectional analysis of 1,576 men aged ≥65 years examined smoking effects on bone status. Number of smoking years was associated with decreased bone mineral density (BMD), after adjusting for age, height, weight, and number of cigarettes smoked daily. Smoking did not affect biochemical marker serum values for bone turnover. Introduction: The impact of smoking on bone status in men has not been conclusively established. We examined how smoking and its cessation influence bone status and metabolism in men. Methods: We analyzed 1,576 men among a baseline survey of Japanese men aged ≥65 years, the Fujiwara-kyo Osteoporosis Risk in Men study, conducted during 2007-2008. Results: Lumbar spine (LS) BMD values among never, former, and current smokers were 1.045 ± 0.194, 1.030 ± 0.189, and 1.001 ± 0.182 g/cm2 (P = 0.005), respectively, while total hip (TH) BMD values were 0.888 ± 0.120, 0.885 ± 0.127, and 0.870 ± 0.124 (P = 0.078), respectively. The significant trend for LS BMD remained after adjusting for the covariates; age, height, weight, physical activity, milk consumption, and drinking habit (P = 0.036). Among never and ever (current and former) smokers, LS and TH BMD decreased with the number of pack years or the number of smoking years, respectively, adjusted for those covariates. Among ever smokers, LS and TH BMD decreased with the number of smoking years after adjusting for age, height, weight, and number of cigarettes smoked daily. Smoking did not reveal significant effect for serum osteocalcin or tartrate resistant acid phosphatase isoenzyme 5b. Conclusion: The impact of smoking on bone status is mainly associated with the number of smoking years in elderly men. © 2010 International Osteoporosis Foundation and National Osteoporosis Foundation.


Fujita Y.,Kinki University | Iki M.,Kinki University | Tamaki J.,Kinki University | Kouda K.,Kinki University | And 7 more authors.
Bone | Year: 2013

End-stage renal failure deteriorates bone mass and increases fracture risk. However, there are conflicting reports in the literature regarding the effects of mild to moderate renal dysfunction on bone mineral density (BMD). We investigated the association between renal function and BMD at the spine and hip and bone metabolism markers in community-dwelling elderly Japanese men. From 2174 male volunteers aged ≥. 65. years, we examined 1477 men after excluding those with diseases or medications known to affect bone metabolism. Renal function was assessed by serum cystatin C and estimated glomerular filtration rate (eGFR) calculated using the Modification of Diet in Renal Disease Study equation. Bone metabolism was evaluated using levels of serum amino-terminal propeptide of type I procollagen (PINP) and tartrate-resistant acid phosphatase isoenzyme 5b (TRACP-5b), which represent bone metabolic status independent of renal function. eGFR was inversely associated with BMD after adjusting for potential confounders (P. <. 0.01). Cystatin C showed a weaker but significant association with BMD. eGFR was modestly positively associated with PINP levels (P. = 0.04), although cystatin C concentrations were neither associated with PINP nor TRACP-5b levels. Since BMD integrates bone metabolism from the past to present, inverse associations between renal function and BMD may be attributed to past factors, such as obesity. Our findings suggest that low renal function does not affect bone metabolism in a population of community-dwelling elderly Japanese men. Longitudinal studies will be necessary to clarify whether low renal function affects bone loss. © 2013 Elsevier Inc.


Kouda K.,Kinki University | Iki M.,Kinki University | Fujita Y.,Kinki University | Tamaki J.,Kinki University | And 8 more authors.
Bone | Year: 2011

There are no data concerning a relationship between alcohol and bone status from a large-scale community-based study of elderly Japanese men. The baseline survey for the Fujiwara-kyo Osteoporosis Risk in Men Study was performed in 2174 male participants during the period from 2007 to 2008 in Nara Prefecture, Japan. Among them 1665 fitted the following inclusion criteria: (a) age ≤65years, (b) no diseases or drug therapy that could affect bone mineral density (BMD). We analyzed 1421 men with complete information about alcohol intake. We found that alcohol intake and BMD were positively correlated after adjustment for age, body mass index, natto intake, milk intake, smoking, physical activity, education, marital status, and hypertension. Adjusted total hip BMD of men with alcohol intake >39g/day was 0.90g/cm 2 and that of abstainers was 0.85g/cm 2. With regard to bone turnover markers, alcohol intake was inversely associated with serum levels of osteocalcin and tartrate-resistant acid phosphatase isoenzyme 5b. A two-piece linear regression model revealed a positive relationship between alcohol intake and crude mean BMD for the total hip in those with alcohol intake of less than 55g/day. In contrast, alcohol intake and BMD in those with an alcohol intake of 55g/day or more was inversely correlated. The present large-scale study of elderly Japanese men revealed that although an alcohol intake of <55g/day was positively correlated to BMD, alcohol intake of ≤55g/day was inversely correlated to BMD. © 2011 Elsevier Inc.


Fujita Y.,Kinki University | Iki M.,Kinki University | Tamaki J.,Kinki University | Kouda K.,Kinki University | And 7 more authors.
Osteoporosis International | Year: 2012

Summary: A cross-sectional analysis of 1,662 community dwelling elderly Japanese men suggested that habitual natto intake was significantly associated with higher bone mineral density (BMD). When adjustment was made for undercarboxylated osteocalcin levels, this association was insignificant, showing the natto-bone association to be primarily mediated by vitamin K. Introduction: Low vitamin K intake is associated with an increased risk of hip fracture, but reports have been inconsistent on its effect on BMD. Our first aim was to examine the association between BMD and intake of fermented soybeans, natto, which contain vitamin K1 (20 μg/pack) and K2 (380 μg/pack). Our second aim was to examine the association between undercarboxylated osteocalcin (ucOC), a biomarker of vitamin K intake, and BMD to evaluate the role of vitamin K in this association. Methods: Of the Japanese men aged ≥65 years who participated in the baseline survey of the Fujiwara-kyo Osteoporosis Risk in Men study, 1,662 men without diseases or medications known to affect bone metabolism were examined for associations between self-reported natto intake or serum ucOC levels with lumbar spine or hip BMD. Results: The subjects with greater intake of natto showed significantly lower level of serum ucOC. Analysis after adjustment for confounding variables showed an association of greater intake of natto with both significantly higher BMD and lower risk of low BMD (T-score < -1 SD) at the total hip and femoral neck. This association became insignificant after further adjustment for ucOC level. Conclusion: Habitual intake of natto was associated with a beneficial effect on bone health in elderly men, and this association is primarily due to vitamin K content of natto, although the lack of information on dietary nutrient intake, including vitamin K1 and K2, prevented us from further examining the association. © 2011 International Osteoporosis Foundation and National Osteoporosis Foundation.


Iki M.,Kinki University | Tamaki J.,Kinki University | Fujita Y.,Kinki University | Kouda K.,Kinki University | And 7 more authors.
Osteoporosis International | Year: 2012

Summary: Recent animal studies have demonstrated that undercarboxylated osteocalcin upregulates insulin secretion via osteoblast-insulin signaling. However, it remains unclear whether such a pathway exists in humans. This study showed that serum undercarboxylated osteocalcin levels were inversely associated with fasting plasma glucose, hemoglobin A 1c, and homeostasis model assessment of insulin resistance (HOMA-IR) levels in community-dwelling elderly Japanese men. Introduction: Undercarboxylated osteocalcin (ucOC) was reported to increase insulin secretion and improve glucose tolerance via osteoblast-insulin signaling in animal-based studies. Whether this pathway also exists in humans is unknown. We aimed to clarify whether serum ucOC levels are associated with glycemic status and insulin resistance in the general Japanese population. Methods: We included 2,174 Japanese men (≥65 years) who were able to walk without aid from others and lived at home in four cities of Nara Prefecture. We excluded participants with a history of diseases or medications that affect bone metabolism, other than type 2 diabetes mellitus (T2DM). Fasting plasma glucose, glycated hemoglobin A 1c, and HOMA-IR levels were determined as outcome measures. Results: Of the 1,597 participants included in the analysis, both intact OC (iOC) and ucOC levels showed significant inverse correlations with all outcome measures, even after adjusting for potential confounders. Mean values of outcome measures showed a significant decreasing trend with higher quintiles of iOC or ucOC after adjusting for confounders. This trend remained significant for ucOC quintiles after further adjustment for iOC levels, but was not significant for iOC quintiles after adjusting for ucOC levels. These results were attenuated, but still apparent, after excluding participants receiving drug therapy for T2DM. Conclusions: Levels of ucOC, but not iOC, were inversely associated with glycemic index and insulin resistance in a population of Japanese men. These findings will need to be confirmed with longitudinal studies. © 2011 International Osteoporosis Foundation and National Osteoporosis Foundation.


Tanaka J.,Benesis Corporation | Nakae T.,Benesis Corporation | Onoe T.,Taisei Gakuin University | Horiuchi Y.,Kinki University | And 4 more authors.
Journal of Infection and Chemotherapy | Year: 2010

A bactericidal mechanism mediated by human serum was investigated by a field emission scanning electron microscope and a strain of drug-resistant Pseudomonas aeruginosa. When the bacteria were treated with meropenem, a carbapenem antibiotic, spheroplasts and bulges (spheroidization) appeared after 1-3 h. When 40% serum was added to the bacteria, the bacteria agglutinated within 2 min and then lysed after 5-30 min. Immunoelectron micrographic analyses showed dispositions of complement component C9 molecules on the cell surface of lysed bacteria by the serum treatment that might suggest formation of a membrane attack complex. Immunoglobulin G (IgG) depletion from the serum diminished the lytic activity and adding human intravenous immunoglobulin (IVIG) restored it, suggesting that lysis was induced by specific IgG binding to the bacteria. IVIG may help patients with less IgG against bacteria to overcome severe infection. © 2010 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases.


Komeda M.,Taisei Gakuin University | Furukawa C.,Taisei Gakuin University
Gan to kagaku ryoho. Cancer & chemotherapy | Year: 2014

The purpose of this study was to clarify whether melamine form has efficacy in preventing skin care during non-invasive positive pressure ventilation in nursing home residents. The study sample comprised 12 people who received non-invasive positive pressure ventilation at a nursing home in Osaka, Japan. Results showed that residents using melamine form had no significant differences in facial shape, though sebum volume, keratinous moisture, impressions, and skin problems were all significantly altered.


Inoue K.,Kobe University | Onoe T.,Taisei Gakuin University | Park P.,Kobe University | Ikeda K.,Kobe University
FEMS Microbiology Letters | Year: 2011

Magnaporthe oryzae germlings tightly attach to the host surface by producing extracellular matrix (ECM) from germ tubes and appressoria, which are important for the early infection process. To understand the adhesion mechanisms of ECM during differentiation of infection structure, we evaluated the effects of various enzymes on M. oryzae germlings and the disease symptoms of the host plant, wheat. Treatment with β-mannosidase, collagenase N-2, collagenase S-1, or gelatinase B at 1-h postinoculation (hpi) resulted in germling detachment, although producing normal appressoria. Treatment with matrix metalloproteinases (MMPs) at 6hpi also caused germling detachment. Furthermore, we confirmed by the inoculation tests and scanning electron microscopy that the germlings on the wheat plant were removed and did not manifest pathogenicity on treatment with MMPs. The most effective MMPs were crude collagenase, collagenase S-1, and gelatinase B, suggesting that the application of MMPs is promising for crop protection from fungal diseases by its detachment action. © 2011 Federation of European Microbiological Societies.


Taisei Gakuin University | Entity website


Taisei Gakuin University | Entity website

> 2016 2016 10001500/ 319() 529() 611() 619() 716() 731() 8 6() 8 7() 827() 828() 910() 925() 1029() > 716() 10:0510:35 2017 10:3510:55 2017 1 11:4512:15 2 14:0014:30 AO AO 12:1012:30 13:0013:30 10:05 / 12:45 / 13:45 () 11:0015:00 10:0015:00 11:3015:00 11:0015:00 11:0015:00 7 11:0015:00 12:3015:00 12:3015:00 1 11:0012:00 2 13:3014:30 12:3015:00 ! 1 11:0012:00 2 13:3014:30 12:3015:00 1 11:0012:00 2 13:3014:30 12:3015:00 1 11:0012:00 2 13:3014:30 12:3015:00 10:4511:45 13:0015:00 13:0014:00() 14:0015:00() 13:0015:00 731() 10:0510:35 2017 10:3510:55 2017 1 11:4512:15 2 14:0014:30 AO AO 12:1012:30 13:0013:30 10:05 / 12:45 / 13:45 () 11:0015:00 10:0015:00 11:3015:00 11:0015:00 11:0015:00 7 11:0015:00 12:3015:00 12:3015:00 1 11:0012:00 2 13:3014:30 12:3015:00 1 11:0012:00 2 13:3014:30 12:3015:00 1 11:0012:00 2 13:3014:30 12:3015:00 1 11:0012:00 2 13:3014:30 12:3015:00 10:4511:45 13:0015:00 13:0014:00() 14:0015:00() 13:0015:00

Loading Taisei Gakuin University collaborators
Loading Taisei Gakuin University collaborators