Chen H.-M.,Taoyuan Armed Forces General Hospital |
Chiou T.-J.,Taipei Veterans Genera Hospital Taipei
Journal of Internal Medicine of Taiwan | Year: 2014
Blood transfusion in some patients has been around conducted for decades. With the popularity of blood transfusion, the clinical benefits and risks of transfusion has been well reported. Among the adverse effects of transfusion, a fatal and serous one is the transfusion-associated graft-versus-host disease, referred to as TA-GvHD. Because of its high mortality rate, so how to prevent its occurrence has become an important clinical issue. Leukocyte reduction and exposure of blood products to irradiation are currently the standard of care for the prevention of TA-GVHD. In this article, we are trying our best to review the occurrence and pathogenesis of TA-GvHD and the methods to prevent its occurrence. (J Intern Med Taiwan 2014; 25:342-349).