Adam A.M.A.,Taif University
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy | Year: 2013
4-Aminoantipyrine (4AAP) is widely used in the pharmaceutical industry, biochemical experiments and environmental monitoring. However, residual amounts of 4AAP in the environment may pose a threat to human health. To provide basic data that can be used to extract or eliminate 4AAP from the environment, the proton-transfer complexes of 4AAP with quinol (QL) and picric acid (PA) were synthesized and spectroscopically investigated. The interactions afforded two new proton-transfer salts named 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H- pyrazol-4-aminium-4-hydroxyphenolate and 1,5-dimethyl-3-oxo-2-phenyl-2,3- dihydro-1H-pyrazol-4-aminium-2,4,6-trinitrophenolate for QL and PA, respectively, via a 1:1 stoichiometry. Elemental analysis (CHN), electronic absorption, spectrophotometric titration, IR, Raman, 1H NMR and X-ray diffraction were used to characterize the new products. The thermal stability of the synthesized CT complexes was investigated using thermogravimetric (TG) analyses, and the morphology and particle size of these complexes were obtained from scanning electron microscopy (SEM). It was found that PA and 4AAP immediately formed a yellow precipitate with a remarkable sponge-like morphology and good thermal stability up to 180 °C. Finally, the biological activities of the newly synthesized CT complexes were tested for their antibacterial and antifungal activities. The results indicated that the [(4AAP)(QL)] complex exhibited strong antimicrobial activities against various bacterial and fungal strains compared with standard drugs. © 2012 Elsevier B.V. All rights reserved.
Elfasakhany A.,Taif University
Energy Conversion and Management | Year: 2014
In this paper, exhaust emissions and engine performance have been experimentally studied for neat gasoline and gasoline/n-butanol blends in a wide range of working speeds (2600-3400 r/min) without any tuning or modification on the gasoline engine systems. The experiment has the ability of evaluating performance and emission characteristics, such as break power, torque, in-cylinder pressure, volumetric efficiency, exhaust gas temperature and concentrations of CO2, CO and UHC. Results of the engine test indicated that using n-butanol-gasoline blended fuels slightly decrease the output torque, power, volumetric efficiency, exhaust gas temperature and in-cylinder pressure of the engine as a result of the leaning effect caused by the n-butanol addition; CO, CO2 and UHC emissions decrease dramatically for blended fuels compared to neat gasoline because of the improved combustion since n-butanol has extra oxygen, which allows partial reduction of the CO and UHC through formation of CO2. It was also noted that the exhaust emissions depend on the engine speed rather than the n-butanol contents. © 2014 Elsevier Ltd. All rights reserved.
Adam A.M.A.,Taif University
Journal of Molecular Structure | Year: 2012
Intermolecular charge-transfer or proton-transfer complexes between the drug procaine hydrochloride (PC-HCl) as a donor and quinol (QL), picric acid (PA) or 7,7′,8,8′-tetracyanoquinodimethane (TCNQ) as a π-acceptor have been synthesized and spectroscopically studied in methanol at room temperature. Based on elemental analyses and photometric titrations, the stoichiometry of the complexes (donor:acceptor molar ratios) was determined to be 1:1 for all three complexes. The formation constant (KCT), molar extinction coefficient (* epsiv;CT) and other spectroscopic data have been determined using the Benesi-Hildebrand method and its modifications. The newly synthesized CT complexes have been characterized via elemental analysis, IR, Raman, 1H NMR, and electronic absorption spectroscopy. The morphological features of these complexes were investigated using scanning electron microscopy (SEM), and the sharp, well-defined Bragg reflections at specific 2θ angles have been identified from the powder X-ray diffraction patterns. Thermogravimetric analyses (TGAs) and kinetic thermodynamic parameters were also used to investigate the thermal stability of the synthesized solid CT complexes. Finally, the CT complexes were screened for their antibacterial and antifungal activities against various bacterial and fungal strains, and only the complex obtained using picric acid exhibited moderate antibacterial activity against all of the tested strains. © 2012 Elsevier B.V. All rights reserved.
Alaoui C.,Taif University
IEEE Transactions on Vehicular Technology | Year: 2013
Battery thermal management system (BTMS) is essential for electric-vehicle (EV) and hybrid-vehicle (HV) battery packs to operate effectively in all climates. Lithium-ion (Li-ion) batteries offer many advantages to the EV such as high power and high specific energy. However, temperature affects their performance, safety, and productive life. This paper is about the design and evaluation of a BTMS based on the Peltier effect heat pumps. The discharge efficiency of a 60-Ah prismatic Li-ion pouch cell was measured under different rates and different ambient temperature values. The obtained results were used to design a solid-state BTMS based on Peltier thermoelectric coolers (TECs). The proposed BTMS is then modeled and evaluated at constant current discharge in the laboratory. In addition, The BTMS was installed in an EV that was driven in the US06 cycle. The thermal response and the energy consumption of the proposed BTMS were satisfactory. © 2012 IEEE.
Sarhan A.M.,Taif University
Artificial Intelligence Review | Year: 2013
Complementary DNA (cDNA) microarray-based tumor gene expression profiles have been successfully used for cancer diagnosis. The main difficulty in processing cDNA microarrays is the ultra-high dimensionality of the microarrays. In this paper, we approach the dimensionality reduction using a novel wavelet-based approach that extracts classification features through microarray-block processing, thresholding, and averaging of approximation coefficients. The proposed cancer detection system presents the extracted features to a support vector machine SVM for classification (tumor or non-tumor). To show the robustness of the proposed system, its performance is tested on two public cancer microarray databases. © 2011 Springer Science+Business Media B.V.
Althomali T.A.,Taif University
Journal of Refractive Surgery | Year: 2013
PURPOSE: To report the outcomes of toric posterior chamber phakic intraocular lens (PIOL) implantation in children for the treatment of amblyopia due to anisometropia with astigmatism. METHODS: Six eyes of 6 amblyopic patients aged 5 to 15 years underwent toric PIOL (Visian Toric ICL; STAAR Surgical Company, Monrovia, CA) implantation for refractory anisometropic amblyopia. Preoperative and postoperative clinical evaluation included slit-lamp microscopy, visual acuity, anterior/posterior segment examination, and cycloplegic refraction. RESULTS: After a mean follow-up of 23 months (range: 15 to 34 months), mean spherical equivalent cycloplegic refraction improved from -10.21 ± 4.62 diopters (D) (range -7.5 to -19.5 D) preoperatively to -0.42 ± 0.39 D (range: -0.625 to +0.125 D) postoperatively. Corrected distance visual acuity ranged from 20/40 to 20/200 preoperatively and 20/20 to 20/60 postoperatively. Five of the 6 eyes gained more than 3 lines of corrected distance visual acuity with a maximum gain of 8 lines in one eye. One eye showed an improvement of more than 2 lines (change in preoperative visual acuity of 20/100 to 20/60 postoperatively). No patients lost any lines of visual acuity. All eyes remained quiet. All PIOLs remained well centered throughout the follow-up period. CONCLUSION: Toric PIOL implantation may be a viable therapeutic modality in children with clinically signifi cant anisometropic ametropia and astigmatism with secondary amblyopia who have been refractory to medical treatment including spectacles or contact lenses. Longer follow-up visits with larger sample populations will evaluate more effectively the long-term effi cacy and late-onset of complications. Copyright © SLACK Incorporated.
Taif University | Date: 2013-10-23
The present invention relates to a pharmaceutical emulsion composition comprising: at least one drug, at least one amino acid, at least one fatty acid and at least one surfactant, wherein the amino acid, the fatty acid and the surfactant form micelles and the drug is encapsulated into the micelles and its use as a medicament, in particular for oral administration in treatment of hyperglycemia and diabetes.
Taif University | Date: 2012-05-02
The present invention relates to a functional food composition, comprising: a thickening agent in an amount from 0.1 to 50% by weight, preferably 1 to 20% by weight; a raising and/or a bulk enhancing agent in an amount from 0.1 to 10% by weight, preferably 0.5 to 3% by weight; at least one edible oil in an amount from 0.1 to 20% by weight, preferably 2 to 10% by weight; at least one additive selected from the group consisting of flavor, surfactant, sweetener, preservative and coloring agent; and water in an amount from 20 to 90% by weight and the use of said functional food composition.
Taif University | Date: 2013-01-31
A method and system for traffic performance analysis, network reconfiguration, and real-time traffic monitoring and surveillance is described. Traffic performance analysis and congestion detection is achieved through discrete event simulation. The road network is translated to a graph. The translation is the result of the processing of a high resolution satellite or aerial image consisting of road extraction. In the resulting graph, road intersections are represented by vertices and road sections by edges. Edges have several properties such as the capacity of the section, presence of traffic signs and traffic lights, rate of generation (vehicles leaving parking), and rate of absorption (vehicles going to parking) Temporal simulation allows detecting congestions as well as congestion propagation. Real-time traffic monitoring consists of detecting abnormal traffic slowdowns. This is achieved by observing traffic with a camera. The video is processed to compute the optical flow which allows the computation of the traffic speed. Individual vehicle speed is also computed to detect speeding vehicles by comparing their speed to the nominal speed limit in the road section. The whole system can be grouped in a traffic control room or a traffic information system.
Taif University | Date: 2014-04-09
The present invention relates to a controlled release pharmaceutical composition comprising at least one pharmaceutically active agent and an excipient matrix, wherein the pharmaceutically active agent is substantially embedded in the excipient matrix and the excipient matrix is a mixture of a wax-like substance and chitosan; as well as to a method for its preparation.