Tabriz University of Medical Sciences
Tabriz, Iran

Tabriz University of Medical science is public medical science university located in Tabriz, East Azarbaijan Province, Iran. It is ranked as one of Iran's top medical schools, with more than 5000 students.The University consists of seven faculties: Medicine, Pharmacy, Dentistry, Paramedical science, Health & Nutrition, Rehabilitation, and Nursing & Midwifery. The school offers professional degrees in Medicine , Dentistry , Pharmacy ; Bachelor's, Master's, and Doctor of Philosophy in various other medically related subjects. The school also offers technical courses in pursuit of Associate's degrees and certification in medically related fields.In addition, TUMS operates over 10 teaching hospitals and is a major medical care provider in East Azarbaijan Province and the surrounding provinces. Wikipedia.

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Meshkini A.,Tabriz University of Medical Sciences
Spine | Year: 2017

STUDY DESIGN.: Case report OBJECTIVE.: To report a case of foreign body mimicking spinal tumor Background: Textiloma, SUMMARY OF BACKGROUND DATA.: Gossypiboma or more broadly Retained Foreign Object (RFO) is a surgical complication resulting from foreign materials such as cotton or gauze pads, surgical sponge, accidentally left inside a patientʼs body. Such foreign materials cause foreign body reaction in the surrounding tissue. METHODS.: A retrospective case report was performed. Informed consent obtained from patient RESULTS.: We describe a case of textiloma in which the patient presented with low- back- pain and radiculopathy 12 years after L5\S1 discectomy. Imaging revealed a round mass lesion in the sacral space. CONCLUSION.: At the end of surgery, the operative site should be flushed with saline and carefully examined for any foreign materials.Level of Evidence: 4 Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

Jaymand M.,Tabriz University of Medical Sciences
Polymer Chemistry | Year: 2014

It is an unquestionable fact that syndiotactic polystyrene (sPS) has stimulated great interest on the basis of its importance in basic scientific research and potential industrial applications. It is regarded as a new low-cost engineering polymer with various desirable properties, such as a high melting temperature (270 °C), fast crystallization rate, low dielectric constant, excellent mechanical properties, low permeability to gases, outstanding dimensional stability, excellent processing characteristics at a very low melt viscosity, and good chemical resistance. However, some drawbacks of sPS restrict its practical use: its brittleness, a disadvantage in applications where mechanical properties are important; the absence of polar groups for adhesion to substrates and compatibility with polar polymers; and the need to process sPS at high temperatures due to its high melting points. Thus, modification of sPS is necessary to expand its applications, and has been the subject of much investigation. This review provides a snapshot of recent progress in the chemical modification of syndiotactic polystyrene, including in situ functionalization of sPS (syndiospecific copolymerization of styrene with a second monomer and catalytic chain transfer to a chain transfer agent), post-functionalization of sPS (introduction of polar groups into sPS, graft or block copolymerization onto sPS, and hydrogenation of sPS or its copolymers) and monomer modification. © 2014 the Partner Organisations.

Danesh-Bahreini M.A.,Tabriz University of Medical Sciences
International journal of nanomedicine | Year: 2011

Leishmaniasis is a protozoan disease, affecting 12 million people in different regions of the world with a wide spectrum of diseases. Although several chemotherapeutic agents have been used for treating the disease, long-term therapy, limited efficacy and the development of drug-resistant parasites remain the major limitations. To develop a new nanovaccine for leishmaniasis, recombinant Leishmania superoxide dismutase (SODB1) was loaded onto chitosan nanoparticles by the ionotropic gelation method. Size and loading efficiency of the nanoparticles were evaluated and optimized, and an immunization study was undertaken on BALB/c mice. The mice received phosphate buffer saline (PBS), superoxide dismutase B1 (SODB1) in PBS and nanoparticles via subcutaneous injection. Soluble Leishmania Antigens (SLA) and complete Freund's adjuvant (CFA) were also injected subcutaneously three times every three weeks (some groups received only a single dose). Three weeks after the last injection, blood samples were collected and assessed with ELISA to detect IgG2a and IgG1. Immunological analysis showed that in single and triple doses of SODB1 nanoparticles, IgG2a and IgG2a/IgG1 were significantly higher than the other groups (P<0.05). The results revealed that formulations of SODB1 in biodegradable and stable chitosan nanoparticles can increase the immunogenicity toward cell-mediated immunity (T(H)1 cells producing IgG2a in mice) that is effective in Leishmania eradication and could be presented as a single dose nanovaccine for leishmaniasis.

Jaymand M.,Tabriz University of Medical Sciences
RSC Advances | Year: 2014

In recent decades, there has been growing interest in the development of organic-inorganic hybrid materials in order to obtain new kinds of materials with synergetic or complementary behavior for various practical and technological applications. Among the numerous kinds of these materials the conductive polymers/zeolite (nano-)composites represent a new class of materials system due to their novel physicochemical properties and potential for various practical and technological applications such as sensors, cathodes of the cells, anticorrosive, membranes, and selective removal of heavy metal ions from sea water and industrial waste water. However, these materials were under-exploited and there were only a few studies conducted for the preparation and application of conductive polymer/zeolite hybrids. This review provides a snapshot of recent progress in the synthesis, materials properties, and applications of conductive polymers/zeolite (nano-)composites reported until March 2014. This journal is © the Partner Organisations 2014.

Jaymand M.,Tabriz University of Medical Sciences
Progress in Polymer Science | Year: 2013

Polyaniline (PANI) has been the subject of considerable recent interest because of their unique electrical behavior, good environmental stability in doped and neutral states, ease of synthesis and wide applications in different fields. However, the main drawback of PANI is lack of solubility, which explains its limited processability due to a rigid backbone. Various procedures have been adapted to improve its processability. The major part of this review is a discussion of some of the methods employed for chemical modification of PANI, including doping via Acid-Base chemistry, sulfonation of PANI or copolymerization of aniline with sulfonated aniline derivatives, synthesis of PANI composites with processable polymers, copolymerization of aniline with substituted corresponding monomers, incorporation of polymeric chains or long and flexible alkyl chains in the PANI backbone, and enzymatic polymerization of aniline during the last decade. © 2013 Elsevier Ltd. All rights reserved.

Ahangarzadeh Rezaee M.,Tabriz University of Medical Sciences
Japanese journal of infectious diseases | Year: 2012

We investigated the prevalence of multidrug resistance, production of extended-spectrum β-lactamases (ESBLs), and presence of class 1 and 2 integrons in 150 clinical isolates of Klebsiella pneumoniae from northwest Iran by performing phenotypic confirmatory tests and polymerase chain reaction (PCR) analysis. Of the 150 isolates, 149 (99.3%) were multidrug resistant (MDR). Of the MDR isolates, 124 (83.2%) were ESBL positive. The results of the PCR analysis showed that 117 (78.5%) and 20 (13.4%) MDR K. pneumoniae isolates carried intI1 and intI2, respectively, and 16 (10.7%) MDR K. pneumoniae isolates contained the integrase genes of both class 1 and class 2. Resistance of the isolates to gentamicin, tetracycline, ceftazidime, cephalothin, chloramphenicol, and nalidixic acid was observed to be significantly associated with the presence of class 1 integrons; however, the resistance to tetracycline was observed to be associated with the presence of class 2 integrons alone. This study showed that integrons are widely prevalent in the clinical isolates of K. pneumoniae from northwest Iran, and that they may be playing an important role in attributing multidrug resistance to the clinical K. pneumoniae isolates. To the best of our knowledge, this is the first report showing the presence of class 1 and class 2 integrons in MDR K. pneumoniae isolates from clinical settings in northwest Iran.

Valizadeh L.,Tabriz University of Medical Sciences
Epilepsy & behavior : E&B | Year: 2013

Epilepsy is a significant health problem in Iran and other countries. Previous epilepsy studies conducted in Iran have often focused on physiological aspects and pharmacological therapy, and little attention has been paid to the psychological and social aspects of care, particularly in adolescence. This paper aims to fill this gap by assessing the relationship between psychosocial care and attitudes toward illness in adolescents with epilepsy. A descriptive correlational design was adopted, and 74 adolescents who experienced generalized seizures and were treated at the neurology clinic affiliated with the Tabriz University of Medical Sciences in 2010 were examined. The data were collected using instruments including (1) the patient demographic characteristics, (2) the Child Report of Psychosocial Care Scale, and (3) the Child's Attitude Toward Illness Scale. There was a significant positive correlation between psychosocial care and attitudes toward illness (p<.05). There is no evidence for routine psychological consultation for our sample; it would be helpful if psychological consultation with and without parents made available to adolescents with epilepsy. Copyright © 2012 Elsevier Inc. All rights reserved.

Badalzadeh R.,Tabriz University of Medical Sciences
Journal of cardiovascular pharmacology and therapeutics | Year: 2012

The interaction of diabetes with cardioprotection by postconditioning in ischemia/reperfusion injury remains unclear. The aim of this study was to investigate the concomitant effects of ischemic postconditioning (IPostC) and cyclosporine-A (CsA) on nitric oxide (NO) content and parameters of cardiac function of the diabetic myocardium injured by ischemia/reperfusion. Diabetes was induced by single injection of streptozotocin (50 mg/kg; intraperitoneally [ip]) in Wistar rats (250-320 g) and the diabetic period was 8 weeks. The hearts (n = 96) were removed quickly, mounted on Langendorff apparatus, and then subjected to 30-minute regional ischemia followed by 45-minute reperfusion. Ischemic postconditioning was induced by 3 cycles of 30-second reperfusion/ischemia at the onset of reperfusion. Myocardial function was measured throughout the experiment, and infarct size (IS) was identified by triphenyltetrazolium chloride (TTC) staining. Total amounts of NO metabolites were determined using Griess method and enzyme-linked immunosorbent assay (ELISA) reader. Administration of either IPostC or CsA alone in nondiabetic animals significantly improved myocardial function and reduced the ISs (28% ± 1.9% or 23% ± 2.0% vs 41% ± 2.9% of the risk zone [RZ], respectively; P < .01), but they had no effect on diabetic hearts (35% ± 1.8% or 32% ± 2.1% vs 39% ± 3.1%, respectively). In addition, myocardial NO level was significantly increased by IPostC only in nondiabetic animals (P < .01). However, after administration of CsA (5 minutes before and 10 minutes after the onset of reperfusion) in postconditioned animals, the cardioprotective and NO-enhancing effects of IPostC were restored in diabetic rats (IS: 21% ± 1.1% vs 39% ± 3.1%), similar to those in nondiabetic controls (19% ± 1.3% vs 41% ± 2.9%; P < .01). The present study indicated that IPostC or CsA failed to affect NO levels and failed to protect the diabetic myocardium against ischemia/reperfusion injury. Moreover, concomitant administration of CsA and IPostC at reperfusion can increase NO content and protect the diabetic myocardium.

Dolatabadi J.E.N.,Tabriz University of Medical Sciences
International Journal of Biological Macromolecules | Year: 2011

Flavonoids occupy an important position in chemistry and pharmacology. Various flavonoids, particularly quercetin have potential to form molecular complexes with nucleic acid structure and have attracted recent attention for their prospective clinical and pharmacological utility. This review highlights the properties of quercetin and its different metal complexes as well as their interactions with DNA reported by several research groups. Various analytical techniques were employed including absorbance, fluorescence and circular dichroism spectroscopies, viscosity and voltammetry to provide more details about binding mechanism of these materials with DNA. © 2010 Elsevier B.V.

Tabrizi A.B.,Tabriz University of Medical Sciences
Journal of Hazardous Materials | Year: 2010

A novel, simple and efficient method for the iron (Fe) speciation and determination in different water samples was developed using dispersive liquid-liquid microextraction (DLLME) technique followed by spectrophotometric analysis. The procedure is based on complexation of Fe(II) with O-phenanthroline (O-Phen), the subsequent ion-association formation with picrate anion, then extraction of the complex using DLLME technique. Some important parameters such as the type and volume of extraction and dispersive solvents as well as the extraction time were investigated and optimized in detail. Under the optimum conditions, the calibration graphs were linear over the range of 0.025-1.0μgmL-1 with limit of detection of 7.5μgL-1. Relative standard deviation for five replicate determinations of Fe at 0.2μgmL-1 concentration level was calculated to be 1.2%. Average recoveries for spiked samples were determined to be between 90% and 108%. The method was applied to water samples and parenteral solutions and the amounts of Fe found in these samples using the proposed method were similar with those obtained by a standard method. © 2010 Elsevier B.V.

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