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Agency: Cordis | Branch: H2020 | Program: CSA | Phase: ISIB-02-2015 | Award Amount: 2.00M | Year: 2016

EuroDairy will foster development and dissemination of practice-based innovations in dairy farming on key sustainability issues for the post-quota era. Work Package 1 (Project co-ordination) oversees formation of the Thematic Network, ensures interconnectivity in generation, capture and demonstration of innovation and best practice, and reports project outputs including recommendations for further innovation-driven research. WP 2 (Network of innovating pilot farmers and Knowledge Transfer Centres) establishes a community of innovating dairy farmers which through experience and practice on their own farms, bring good ideas and implementable solutions to EuroDairy. The farms participate in regional multi-actor operational groups, and connect as a network to share knowledge across borders. WPs 3-6 focus on four key topics - Resource efficiency, Biodiversity, Animal care, and Socio-economic resilience. These WPs provide leadership, direction and technical expertise for the exchange of innovative thinking, tools, technologies and best practice across the thematic network (pilot farmers, Knowledge Transfer Centres, and regional operational groups). WP 7 (Synergies in scientific and practice-based knowledge) draws from WPs 3-6 to capture new insights from combining science with practice-based knowledge, including benefits and trade-offs in solutions identified. WP 8 (Production and communication of end-user materials) implements a mix of novel and tried-and-tested approaches to internal and external communications. A diverse range of end-user outputs will be produced, made widely accessible to farmers. EuroDairy supports H2020 objectives to increase productivity, improve competitiveness and impact less on the environment. Involvement of dairy levy bodies, farmers organisations and cooperatives in an interactive, bottom-up approach will ensure practical relevance, and multiply benefits across Europe. Direct links to Hennovation and AgriSPIN, will add value to the project.

Agency: Cordis | Branch: H2020 | Program: RIA | Phase: SFS-01b-2014 | Award Amount: 10.52M | Year: 2015

SAPHIR aims to develop vaccine strategies effective against endemic pathogens responsible for high economic losses in livestock in order to strengthen the profitability of food animal systems, improve animal welfare and reduce xenobiotic usage in farming with a One Health perspective. SAPHIR will bring novel vaccine strategies to the market i) at short term, with several promising vaccines brought to demonstration (RTL6), ii) at long term, with cutting edge strategies brought at proof of concept (RTL3) and iii) in line with socio-economic requirements. SAPHIR has selected two representative pathogens of pigs (Porcine Reproductive and Respiratory Syndrome Virus and Mycoplasma hyopneumoniae), chickens (Eimeria and Clostridium perfringens) and cattle (Bovine Respiratory Syncytial Virus, Mycoplasma bovis) to develop generic vaccine approaches applicable to other pathogens. SAPHIR will issue i) knowledge of immune mechanisms of protection, ii) affordable, safe and multivalent vaccines with DIVA properties, iii) efficient adjuvants targeting dendritic cells, optimal formulations, new mucosal and skin delivery systems, a new generation of DNA vectors and viral replicon platforms for fostering an earlier and longer duration of immunity including the perinatal period, and iv) basal biomarkers of individual immuno-competence for future breeding strategies. The SAPHIR dissemination and training programme includes creation of an integrated health management website, launch of a Global Alliance for Veterinary Vaccines and organization of workshops directed at food animal system stakeholders. This will ensure optimal research translation of SAPHIR outputs to market and field applications. SAPHIR brings together interdisciplinary expertise from fourteen academic institutes including a Chinese partner, five SMEs and two pharmaceutical companies.

Agency: Cordis | Branch: FP7 | Program: CP-IP | Phase: ENV.2011.2.1.2-1 | Award Amount: 8.88M | Year: 2011

REFORM is targeted towards development of guidance and tools to make river restoration and mitigation measures more cost-effective and to support the 2nd and future River Basin Management Plans (RMBPs) for the WFD. Aims of REFORM are (1) to provide a framework for improving the success of hydromorphological restoration measures and (2) to assess more effectively the state of rivers, floodplains and connected groundwater systems. The restoration framework addresses the relevance of dynamic processes at various spatial and temporal scales, the need for setting end-points, analysis of risks and benefits, integration with other societal demands (e.g. flood protection and water supply), and resilience to climate change. The consortium comprises scientists and practitioners covering a wide range of disciplines (hydrology, hydraulics and geomorphology, ecology, socio-economics). The workplan is organized in three modules: (1) natural processes, (2) degradation, (3) restoration. Data from monitoring programmes and restoration projects will be pooled and linked with landscape-scale hydromorphological and physiographic data and catchment models. Targeted field and experimental studies using common protocols will fill data gaps on the role of scale in restoration success. A wide range of statistical modeling approaches will improve indicators for hydromorphological change and factors determining restoration success. All work packages are multidisciplinary and will feed into products for application in river basin management, e.g. guidelines for successful restoration and a web-based tool for exchanging experiences with river restoration measures facilitated and enhanced through consultation with stakeholders. In addition to its impact on the RBMPs, REFORM will provide guidance to other EU directives (groundwater, floods, energy from renewable resources, habitats) to integrate their objectives into conservation and restoration of rivers as sustainable ecosystems

Agency: Cordis | Branch: FP7 | Program: CP-TP | Phase: KBBE.2013.1.3-03 | Award Amount: 12.00M | Year: 2013

Production diseases compromise health and welfare, generating inefficiencies which impact adversely on profitability, environmental footprint, antibiotic use and product quality. The PROHEALTH project will develop understanding of the multi-factorial dimension of animal pa-thologies linked to the intensification of production and use this to develop, evaluate and disseminate ef-fective control strategies to reduce impact. It will address production diseases of pigs and poultry raised in a wide range of EU intensive systems, using both epidemiological and experimental approaches to consider the extent of, and the risk factors associated with diseases, the influence of genotype and its modification by early life experience, and the dynamic influences of the environment on disease. The mechanisms underlying differences in disease susceptibility will be explored at different levels. Improvement strategies for diseases including neo-natal mortality, gut and respiratory disorders, leg and metabolic disorders will be evaluated in farm scale tests, and data from diverse systems used to model whole-chain socioeconomic implications of disease states and their alleviation. The consortium has expertise in veterinary science and epidemiology, physiology and immunology, ge-netics, nutrition, socioeconomics, welfare and production science of pigs and poultry. The 10 academic, 1 association 4 industry and 7 SME partners cover the full European geographic range to derive meaningful epidemiological data and test interventions across diverse production circumstances. Dissemination activities will encompass all stakeholders in the food chain and establish new e-learning tools. PROHEALTH will deliver novel diagnostics for the propensity to develop production diseases and their occurrence, and multifactorial improvement strategies that can be applied to produce better quality products in a welfare friendly manner and improve competitiveness and sustainability of EU pig & poultry systems

Agency: Cordis | Branch: FP7 | Program: CP-IP | Phase: KBBE.2010.2.2-02 | Award Amount: 11.95M | Year: 2011

NU-AGE is a large multidisciplinary consortium (30 partners, from 16 EU countries) involving nutritionists, biogerontologists, immunologists and molecular biologists from the most prestigious institutions in Europe, 5 large food industries, 8 traditional food companies and 1 biotech SME, SPES GEIE and FooDrinkEurope, covering the SME Food Industrial Associations of 13 European countries and the European Confederation the food and drink industry. NU-AGE aims are: 1. to counteract the physical/cognitive decline occurring in the elderly as a consequence of the progressive alteration of different organs/systems (immune and cardiovascular systems, bone, brain, muscle and intestine) by one year elderly-tailored whole diet intervention on 1250 healthy elderly men and women aged 65-79 years (half diet, half control) from 5 different EU regions; 2. to assess the effect of the newly designed food pyramid specific for 65\ EU citizens on the different organs/systems using a large set of biomarkers related to nutrition and ageing, with particular attention to the low grade, chronic, systemic inflammatory status named inflammageing, a major risk factor for common age-related diseases; 3. to perform in a subgroup of 120 subjects in depth studies and high throughput omics to identify cellular/molecular targets/mechanisms responsible for whole diet effect; 4. to perform genetic and epigenetic studies to assess the role of individual variability on the response to diet; 5. to adopt an integrative comprehensive approach (systems biology) to analyze the whole set of data. The results of dietary intervention will be used to develop elderly-tailored prototypes of functional foods and to improve traditional foods. The research activity will be accompanied and followed by a strong activity of dissemination and industrial exploitation to support EU strategies on nutritional recommendations, thus contributing to the implementation of legislation related to nutritional and health claims for elderly in Europe.

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