Syracuse University, commonly referred to as Syracuse, 'Cuse, or SU, is a private research university located in Syracuse, New York. The institution's roots can be traced to the Genesee Wesleyan Seminary , founded by the Methodist Episcopal Church in Lima, New York, in 1831. Following several years of debate over relocating the college to Syracuse, the university was established in 1870, independent of the college. Since 1920, the university has identified itself as nonsectarian, although it maintains a relationship with The United Methodist Church.The campus is located in the University Hill neighborhood of Syracuse, east and southeast of downtown, on one of the larger hills. Its large campus features an eclectic mix of buildings, ranging from nineteenth-century Romanesque Revival structures to contemporary buildings. SU is organized into 13 schools and colleges, with nationally recognized programs in information studies and library science, architecture, communications, business administration, sport management, public administration, engineering and the College of Arts and science.Syracuse University athletic teams, known as the Orange, participate in 20 intercollegiate sports. SU is a member of the Atlantic Coast Conference for all NCAA Division I athletics, except for women's ice hockey, and the rowing team. SU is also a member of the Eastern College Athletic Conference. Wikipedia.
Syracuse University | Date: 2016-09-01
Small molecule ghrelin O-acyltransferase inhibitors found using an assay to detect ghrelin O-acyltransferase activity using an acrylodan-labeled peptide mimic of ghrelin that provides for high-throughput screening for ghrelin O-acyltransferase inhibitors and detection via high performance liquid chromatography. The newly discovered class of synthetic triterpenoids efficiently inhibits ghrelin acylation by GOAT and function as covalent reversible inhibitors of GOAT. In cell studies, the most potent members of this family of compounds efficiently block ghrelin acylation at submicromolar concentrations and offer a foundation for continued development and evaluation of novel hGOAT inhibitors as therapeutics targeting disorders such obesity, type II diabetes, gastroparesis, and Prader-Willi syndrome.
Syracuse University | Date: 2016-09-02
A system of topographic patterns for the prevention of bacterial adhesion and biofilm formation. The patterns may be provided on the surfaces of certain devices that are prone to bacterial adhesion and biofilm formation, such as urinary catheters. To reduce bacterial adhesion and biofilm formation, and to remove existing biofilms, the patterns are induced to transform from a first topography to a second topography. For example, the surface patterns may be formed from a shape memory polymer and then heated to transform the patterns from the first topography to the second topography to dislodge bacteria and prevent fouling.
Syracuse University | Date: 2016-09-23
A method for characterizing at least a portion of the biodiversity of a sample. The method includes the steps of: (i) obtaining a sample having nucleic acid from a plurality of different organisms; (ii) extracting at least a portion of the nucleic acid from the sample; (iii) optionally performing a whole-genome amplification of the extracted nucleic acid; (iv) optionally performing a second, targeted amplification; (v) sequencing the amplified nucleic acid to obtain sequence data comprising a nucleic acid sequence for at least some of the plurality of different organisms; (vi) querying, using the obtained sequence data, a sequence database, where querying the sequence database identifies one or more of the plurality of different organisms; and (vii) determining, using the identified one or more of the plurality of different organisms, a characteristic of the sample.
Syracuse University | Date: 2016-10-26
A self-replenishing biocompatible hydrogel having a zwitterionic polymer embedded throughout the matrix system to act as a lubricant and a surface modified with the same zwitterionic polymer. When surface material loss occurs in the hydrogel, such as a surface crack or a scratch, the damage propagates through the matrix rupturing the pockets of lubricant. The zwitterionic polymer is then drawn into the site due to the change in entropy at the surface and the positive and negative charge groups of the side chains fuse across the damage cite due to strong electrostatic attraction causing inter-chain association.
Syracuse University | Date: 2017-02-14
The present invention describes the use of nanoparticle interfaces to chemically process solid nanomaterials into ones with tailorable core-void-shell architectures. The internal void sizes are proportional to the nanoparticle size, the shell thickness and composition, and can be either symmetric or asymmetric depending on the nature of the interface, each of which is controlled by the process of making.
Syracuse University | Date: 2015-12-03
A method for determining the presence or absence of an illicit plant-derived compound in a sample. The method includes the steps of: (i) providing a sample potentially containing an illicit plant-derived compound; (ii) extracting DNA in the illicit plant-derived compound from the identified sample; (iii) amplifying, using PCR, the target plant DNA sequence from the extracted DNA; and (iv) detecting an amplified target plant DNA sequence, where detection of the amplified target plant DNA sequence indicates the presence of the illicit plant-derived compound.
Syracuse University | Date: 2016-12-02
A system configured to characterize a ratio of contributors to a DNA mixture within a sample, the system including: a sample preparation module configured to generate initial data about the DNA mixture within the sample; a processor comprising a ratio of contributors determination module configured to: (i) receive the generated initial data; (ii) analyze the generated initial data to determine the ratio of contributors to the DNA mixture within the sample; and an output device configured to receive the determined ratio of contributors from the processor, and further configured to output information about the received determined ratio of contributors.
Syracuse University | Date: 2016-12-08
A porous solid oxide fuel cell (PSOFC) system for electricity and syngas co-generation. The system has a porous layer, a porous electrolyte layer with catalyst, a porous anode layer, and a porous catalyst layer. A fuel air/O_(2 )mixture is introduced from through the porous cathode layer so that it next passes through the porous electrolyte layer with catalyst, then the porous anode layer, and finally the porous catalyst layer. Syngas exits the porous catalyst layer with electricity being produced across the anode and cathode layers.
Zhang P.,Syracuse University
MIS Quarterly: Management Information Systems | Year: 2013
Affect is a critical factor in human decisions and behaviors within many social contexts. In the information and communication technology (ICT) context, a growing number of studies consider the affective dimension of human interaction with ICTs. However, few of these studies take systematic approaches, resulting in inconsistent conclusions and contradictory advice for researchers and practitioners. Many of these issues stem from ambiguous conceptualizations of various affective concepts and their relationships. Before researchers can address questions such as "what causes affective responses in an ICT context" and "what impacts do affective responses have on human interaction with ICTs," a theoretical foundation for affective concepts and their relationships has to be established. This theory and review paper addresses three research questions: (1) What are pertinent affective concepts in the ICT context? (2) In what ways are these affective concepts similar to, or different from each other? (3) How do these affective concepts relate to or influence one another? Based on theoretical reasoning and empirical evidence, the affective response model (ARM) is developed. ARM is a theoretically bound conceptual framework that provides a systematic and holistic reference map for any ICT study that considers affect. It includes a taxonomy that classifies affective concepts along five dimensions: the residing, the temporal, the particular/general stimulus, the object/behavior stimulus, and the process/outcome dimensions. ARM also provides a nomological network to indicate the causal or co-occurring relationships among the various types of affective concepts in an ICT interaction episode. ARM has the power for explaining and predicting, as well as prescribing, potential future research directions. Copyright © 2013 by the Management Information Systems Research Center (MISRC) of the University of Minnesota.
Vidali G.,Syracuse University
Chemical Reviews | Year: 2013
The importance of understanding how molecular hydrogen is formed in space is 4-fold. Rapid progress in surface science, and especially in the interaction of atoms or molecules with surfaces, was obtained in the 1980s and 1990s in part due to availability of ultrahigh vacuum techniques and the use of single crystal surfaces for which cleaning and characterization methods could be readily established. Improvements in the application of DFT to atom-surface interaction have led to a more accurate handling of the interaction at large distances where weak dispersion-like forces should dominate. The first involves long-range dispersion forces and the characteristics energies are in the tens to a few hundred meV, while chemisorption is about eV energies and chemical bonding. Obviously, this is just a coarse way to categorize an otherwise wide range of complex interactions.