French National Institute for Agricultural Research and Synchrotron Soleil | Date: 2016-04-27
The invention relates to a tandem mass spectrometer comprising an ionization source that can produce ions; a mass analyser comprising an ion trap arranged in such a way as to receive ions from the ion source and a detector that can detect ions leaving the ion trap according to the mass to charge (m/z) ratio thereof; ion activation means for activating ions that can fragment at least some of the ions trapped in the ion trap; and coupling means arranged between the ion trap and said ion activation means. According to the invention, the ion activation means consists of a glow discharge lamp that can generate a light beam oriented towards the ion trap, said light beam being electromagnetic radiation in the vacuum ultraviolet wavelength range with photon energies of between 8 eV and 41 eV in such a way as to fragment at least some of the ions trapped in the ion trap.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: INFRAIA-1-2014-2015 | Award Amount: 10.00M | Year: 2015
Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials. iNEXT (infrastructure for NMR, EM and X-rays for Translational research) will provide high-end structural biology instrumentation and expertise, facilitating expert and non-expert European users to translate their fundamental research into biomedical and biotechnological applications. iNEXT brings together leading European structural biology facilities under one interdisciplinary organizational umbrella and includes synchrotron sites for X-rays, NMR centers with ultra-high field instruments, and, for the first time, advanced electron microscopy and light imaging facilities. Together with key partners in biological and biomedical institutions, partners focusing on training and dissemination activities, and ESFRI projects (Instruct, Euro-BioImaging, EU-OPENSCREEN and future neutron-provider ESS), iNEXT forms an inclusive European network of world class. iNEXT joint research projects (fragment screening for drug development, membrane protein structure, and multimodal cellular imaging) and networking, training and transnational access activities will be important for SMEs, established industries and academics alike. In particular, iNEXT will provide novel access modes to attract new and non-expert users, which are often hindered from engaging in structural biology projects through lack of instrumentation and expertise: a Structural Audit procedure, whereby a sample is assessed for its suitability for structural studies; Enhanced Project Support, allowing users to get expert help in an iNEXT facility; and High-End Data Collection, enabling experienced users to take full benefit of the iNEXT state-of-the-art equipment.
Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2015-ETN | Award Amount: 3.18M | Year: 2016
In the ASPIRE project, whose academic and industrial beneficiaries are world leading in their complementary fields of expertise, the overarching research goal is the measurement of photoelectron angular distributions (PADs) in the molecular frame (MF) of systems of biological relevance. These MF-PADs can be interpreted as electron diffraction patterns, achieved by illuminating the molecule from within, and enable the shapes and motions of individual molecules to be interrogated. Such knowledge is needed for the development of new medicines (the shapes of drug molecules dictate their function) and new materials (efficient solar cells can be constructed if energy dissipation processes in molecules are understood). Progress in this area is highly technologically driven, requiring high repetition rate, short wavelength light sources and fast detectors. The input of private sector beneficiaries is therefore critical to the scientific objectives, as well as to the enhanced training environment. Work packages on advanced light source and detector developments will feed into the overall goal through secondments, regular virtual meetings and face-to-face network meetings. The symbiosis of the developments that will take place in ASPIRE will create a research and training environment that is world-leading and optimally tailored to capitalise, for example, on the investment that has been made in the European XFEL facility. The ESRs will be trained in world-leading laboratories and will benefit from the exchange of best practice among beneficiaries and partners, and from unique training events. ASPIRE will therefore ensure that European research remains competitive in the global market, and that the trained researchers will be uniquely well-placed to contribute to the development of novel instrumentation in the future.
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: INFRASUPP-01-2016 | Award Amount: 2.10M | Year: 2017
The OPEN SESAME project will ensure optimal exploitation of the Synchrotron light for Experimental Science and Applications in the Middle East (SESAME) light source. With this aim, OPEN SESAME has three key objectives: 1. To train SESAME staff in the storage ring and beamline instrumentation technology, research techniques and administration for optimal use of a modern light source facility. 2. To build-up human capacity in Middle East researchers to optimally exploit SESAMEs infrastructure. 3. To train SESAME staff and its user community in public outreach and corporate communications, and to support SESAME and its stakeholders in building awareness and demonstrating its socio-economic impact to assure longer term exploitation. Each objective is tackled by a work package. Firstly, SESAME staff training is addressed by 65 staff exchanges planned between SESAME and the European partners. Secondly, capacity-building is targeted by five training schools, a short-term fellowship programme and an industrial workshop. Finally, a proactive communications strategy will be created, including an educational roadshow to all of the SESAME Members, and a training programme in research infrastructure administration and their economic role and impact for young science managers of SESAME Member stakeholders. The project directly addresses the INFRASUPP-2016-2017 call to support SESAME. OPEN SESAME is well aligned to the broader scope of the work programme with activities that will have a lasting impact on a reinforced European Research Area, and particularly in strengthening international cooperation for research infrastructures with a key Region located close to Europe. The project has been developed closely with SESAME, its Directors and international Training Advisory Committee. The OPEN SESAME consortium is composed of ten European institutes (six light sources, The Cyprus Institute, CERN, CNRS and Instruct) along with SESAME itself.
Agency: European Commission | Branch: FP7 | Program: CP-CSA-Infra | Phase: INFRA-2012-1.1.24. | Award Amount: 23.40M | Year: 2013
Research accelerators are facing important challenges that must be addressed in the years to come: existing infrastructures are stretched to all performance frontiers, new world-class facilities on the ESFRI roadmap are starting or nearing completion, and strategic decisions are needed for future accelerators and major upgrades in Europe. While current projects concentrate on their specific objectives, EuCARD-2 brings a global view to accelerator research, coordinating a consortium of 40 accelerator laboratories, technology institutes, universities and industry to jointly address common challenges. By promoting complementary expertise, cross-disciplinary fertilisation and a wider sharing of knowledge and technologies throughout academia and with industry, EuCARD-2 significantly enhances multidisciplinary R&D for European accelerators. This new project will actively contribute to the development of a European Research Area in accelerator science by effectively implementing a distributed accelerator laboratory in Europe. Transnational access will be granted to state-of-the-art test facilities, and joint R&D effort will build upon and exceed that of the ongoing EuCARD project. Researchers will concentrate on a few well-focused themes with very ambitious deliverables: 20 T accelerator magnets, innovative materials for collimation of extreme beams, new high-gradient high-efficiency accelerating systems, and emerging acceleration technologies based on lasers and plasmas. EuCARD-2 will include six networks on strategic topics to reinforce synergies between communities active at all frontiers, extending the scope towards innovation and societal applications. The networks concentrate on extreme beam performance, novel accelerator concepts with outstanding potential, energy efficiency and accelerator applications in the fields of medicine, industry, environment and energy. One network will oversee the whole project to proactively catalyze links to industry and the innovation potential.
French Institute of Health, Medical Research, Synchrotron Soleil and University Paris - Sud | Date: 2016-06-01
The present invention relates to a method for measuring a biological value Vb in a liver wherein said method comprises the steps of: a/ applying an infrared radiation having at least a first wave number range between 2800 cm^(1 )and 3000 cm^(1 )to one or more portions, p_(i), of a sample of said liver, b/ detecting the intensity of the radiation after it has passed through each of one or more portions, p_(i), and generating a signal related to the detected intensity. c/ processing the generated signal(s) to calculate an average value v_(a); d/ comparing said average value V_(a )to a standard to obtain the biological value Vb.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: INFRAIA-1-2014-2015 | Award Amount: 8.16M | Year: 2015
IPERION CH aims to establish the unique pan-European research infrastructure in Heritage Science by integrating national world-class facilities at research centres, universities and museums. The cross-disciplinary consortium of 23 partners (from 12 Member States and the US) offers access to instruments, methodologies and data for advancing knowledge and innovation in the conservation and restoration of cultural heritage. Fourth in a line of successful projects (CHARISMA-FP7, Eu-ARTECH-FP6 and LabS-TECH network-FP5), IPERION CH widens trans-national access by adding new providers with new expertise and instruments to the three existing complementary platforms ARCHLAB, FIXLAB and MOLAB. The quality of access services will be improved through joint research activities focused on development of new advanced diagnostic techniques and (with DARIAH ERIC) tools for storing and sharing scientific cultural heritage data. Networking activities will (a) promote innovation through technology transfer and dynamic involvement of SMEs; (b) improve access procedures by setting up a coordinated and integrated approach for harmonising and enhancing interoperability among the facilities; (c) identify future scientific challenges, best practices and protocols for measurements; (d) optimise the use of digital tools in Heritage Science. To advance the international role of EU cultural heritage research, IPERION CH will generate social and cultural innovation by training a new generation of researchers and professionals and by worldwide dissemination and communication to diverse audiences. To ensure long-term sustainability, the advanced community of IPERION CH will work towards inclusion in the new ESFRI Roadmap and constitution of a RI with its own EU legal entity (e.g. ERIC). Synergies with national and local bodies, and with managing authorities in charge of ESIF, will expand the scope and impact of IPERION CH in terms of competitiveness, innovation, growth and jobs in ERA.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: INFRADEV-1-2014 | Award Amount: 3.00M | Year: 2015
EuPRAXIA will produce a conceptual design report for the worldwide first 5 GeV plasma-based accelerator with industrial beam quality and user areas. EuPRAXIA is the required intermediate step between proof-of-principle experiments and ground-breaking, ultra-compact accelerators for science, industry, medicine or the energy frontier (plasma linear collider). The study will design accelerator technology, laser systems and feedbacks for improving the quality of plasma-accelerated beams. Two user areas will be developed for a novel Free Electron Laser and High Energy Physics detector science. An implementation model will be proposed, including a comparative study of possible sites in Europe, a cost estimate and a model for distributed construction and installation at one central site. EuPRAXIA will be a new large research infrastructure with an estimated footprint of about 250 m. If the design study is approved, then it will lay the foundation for a possible decision on construction in 2020. A consortium of 16 laboratories and universities from 5 EU member states has formed for preparing this proposal. 18 associated partners from 8 countries have joined with in-kind commitments (linking 3 additional EU member states). The scientists represent expertise from accelerator operation for photon science and HEP, design and construction of leading accelerators like LHC and Soleil, advanced acceleration test facilities like SPARC and frontier laser projects like CLF, CILEX-APOLLON and ELI. A project with 14 work packages has been defined, 8 of them with funding requested from EU. The proposal has been discussed in the European Steering Group for Accelerator R&D (ESGARD). A statement of strong support has been received. The EuPRAXIA technology is closely linked to EU industry. The director of the THALES Laser Business Unit and the CEO of Amplitude Technologies have sent letters of strong support for the EuPRAXIA proposal.