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Nanded, India

Swami Ramanand Teerth Marathwada University was established in 1994. Named after Swami Ramanand Teerth, it is located at Nanded in Maharashtra, India. The university is intended to serve primarily the southern part of Marathwada, specifically the districts of Nanded, Latur, Parbhani, and Hingoli. The main university campus, which is about 10 km south of Nanded township, occupies approximately 525 acres , and there is a 22-acre sub-campus at Latur. Wikipedia.

Deosarkar S.D.,Swami Ramanand Teerth Marathwada University
Russian Journal of Physical Chemistry A

The density, viscosity and ultrasonic velocity of some substituted pyrazoles viz. 5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4-benzoylpyrazol, 5-(2-hydroxyphenyl)-3-(3-nitrophenyl)-4-(3-pyridinoyl)-pyrazol, 5-(2-hydroxyphenyl)-3-(3-nitrophenyl)-4-benzoylpyrazol and 5-(2-hydroxyphenyl)- 3-phenyl-4-(3-pyridinoyl)-pyrazole have been measured in 70: 30 (vol/vol) acetone-water mixture at 298, 303, 308, and 313 K for 0.01 mol dm -3 concentration of pyrazoles. The acoustical parameters such as adiabatic compressibility (β s), relative association (R A), specific acoustic impedance (Z), apparent molar volume (φ v), apparent molar adiabatic compressibility (φ K), and intermolecular free length (L f) were calculated from the experimental densities and velocities. The changes in acoustical properties have been used to interpret the molecular interactions in solutions. The activation energies of viscous flow of pyrazole solutions were determined from the data of viscosity at different temperature. © 2012 Pleiades Publishing, Ltd. Source

Joshi Y.S.,Lal Bahadur Shastri Mahavidyalaya | Kumbharkhane A.C.,Swami Ramanand Teerth Marathwada University
Fluid Phase Equilibria

The complex permittivity of 2-butoxyethanol (BE)-water mixtures over entire concentrations has been measured as a function of frequency from 10MHz to 30GHz. All spectra were fitted using Cole-Davidson (CD) relaxation spectral function which gives an asymmetric distribution of relaxation times. As composition of butoxyethanol in water increases the width of distribution function broadens. By using least squares fit method the dielectric parameters such as static dielectric constant (e{open} 0), dielectric constant at high frequency (e{open} ∞), relaxation time (τ) and relaxation distribution parameter (β) were extracted from complex permittivity spectra at temperature range from 25°C to 0°C. The heterogeneous interaction in unlike molecules and intramolecular interaction in same molecules has been discussed using the excess dielectric properties, Kirkwood correlation factor, thermodynamic properties and Bruggeman factor. © 2012 Elsevier B.V. Source

Chaudhari A.,Swami Ramanand Teerth Marathwada University
International Journal of Quantum Chemistry

This work reports an interaction of 1,4-dioxane with one, two, and three water molecules using the density functional theory method at B3LYP/6- 311++G * level. Different conformers were studied and the most stable conformer of 1,4-dioxane-(water)n (n = 1-3) complex has total energies -384.1964038, -460.6570694, and -537.1032381 hartrees with one, two, and three water molecules, respectively. Corresponding binding energy (BE) for these three most stable structures is 6.23, 16.73, and 18.11 kcal/mol. The hydrogen bonding results in red shift in O-O stretching and C-C stretching modes of 1,4-dioxane for the most stable conformer of 1,4-dioxane with one, two, and three water molecules whereas there was a blue shift in C-O symmetric stretching and C-O asymmetric stretching modes of 1,4-dioxane. The hydrogen bonding results in large red shift in bending mode of water and large blue shift in symmetric stretching and asymmetric stretching mode of water. © 2009 Wiley Periodicals, Inc. Source

Gacche R.N.,Swami Ramanand Teerth Marathwada University

Since the establishment of tumor angiogenesis as a therapeutic target, an excitement in developing the anti-angiogenic agents was resulted in tailoring a humanized monoclonal antibody (Bevacizumab) against vascular endothelial growth factor (VEGF): a key factor in recruiting angiogenesis. The past three decades' research in the area of angiogenesis also invented a series of novel and effective anti-angiogenic agents targeting the VEGF signaling axis. Despite the demonstrable clinical benefits of anti-angiogenic therapy, the preclinical and clinical data of the current therapeutic settings clearly indicate the transient efficacy, restoration of tumor progression and aggressive recurrence of tumor invasion after the withdrawal of anti-angiogenic therapy. Therefore, the impact of this therapeutic regime on improving overall survival of patients has been disappointing in clinic. The recent advances in pathophysiology of tumor angiogenesis and related molecular and cellular underpinnings attributed the conspiracy of compensatory angiogenic pathways in conferring evasive and intrinsic tumor resistance to anti-angiogenic agents. The understandings of how these pathways functionally cross-talk for sustaining tumor angiogenesis during VEGF blockade is essential and perhaps may act as a basic prerequisite for designing novel therapeutic strategies to combat the growing arrogance of tumors toward anti-angiogenic agents. The present review offers a discourse on major compensatory angiogenic pathways operating at cellular and molecular levels and their attributes with resistance to anti-angiogenic agents along with strategic opinions on future setting in targeting tumor angiogenesis. Source

Deosarkar S.D.,Swami Ramanand Teerth Marathwada University
Russian Journal of Physical Chemistry A

Densities and refractive indices of KOH solutions of three different concentrations in solutions of ethanol in water with different concentrations were measured at 303.15 K. From densities and refractive indices the specific refractions and molar refractions were estimated and interpreted in terms of molecular interactions. Concentration dependence of (n D 2 - 1)/(n D 2 + 2) has been studied. © 2013 Pleiades Publishing, Ltd. Source

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