SUNTORY HOLDINGS Ltd and Suntory Ltd | Date: 2013-03-05
Processed health food, dietary and nutritional supplements, in granular, powder, capsular, liquid and bar form containing tea extract as a major ingredient. Health food in granular, powder, capsular, liquid and bar form containing tea as a major ingredient, namely, soy or vegetable based snack foods. Tea; coffee and cocoa; confectionery, namely, candy, frozen confectionery, fondants; bread and buns; seasonings other than spices; unprocessed coffee, namely, un-roasted coffee; cereal preparations, namely, ready-to-eat cereals, cereal based snack foods.
Suntory Holdings Ltd and SUNTORY Ltd | Date: 2009-03-03
Suntory Holdings Ltd and SUNTORY Ltd | Date: 2009-03-10
Artificial plant cultivation soil; artificial plant cultivation soil made of mineral materials; artificial plant cultivation soil made of plastic materials; planting soil; potting soil; fertilizers; compost; potting compost; peat pots for horticultural use; artificial plant cultivation compost; and artificial plant cultivation compost made of peat moss and urethane materials.
Ogawa E.,Shinshu University |
Ogawa E.,Tohoku University |
Owada Y.,Yamaguchi University |
Ikawa S.,Tohoku University |
And 10 more authors.
Journal of Investigative Dermatology | Year: 2011
Fatty acid-binding proteins (FABPs) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. Epidermal FABP (E-FABP/FABP5) is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. In this study, we found decreased expression of the differentiation-specific proteins keratin 1, involucrin, and loricrin in E-FABP / keratinocytes relative to E-FABP / keratinocytes. We also determined that incorporation of linoleic acid was significantly reduced in E-FABP / keratinocytes. Although linoleic acid did not directly affect keratinocyte differentiation, keratin 1 expression was induced by the linoleic acid derivative 13(S)-hydroxyoctadecadienoic acid (13(S)-HODE), and this induction was concomitant with increased NF-B activity. In E-FABP / keratinocytes, the expression of 13(S)-HODE and the subsequent induction of NF-B activity was lower than in wild-type keratinocytes. The reduction of linoleic acid in E-FABP / keratinocytes led to decreased cellular 13(S)-HODE content, resulting in decreased keratin 1 expression through downregulation of NF-B activity. The regulation of fatty acid metabolism by E-FABP during keratinocyte differentiation suggests that E-FABP may have a role in the pathogenesis of psoriasis. © 2011 The Society for Investigative Dermatology. Source