Sunjin Co.

Seoul, South Korea

Sunjin Co.

Seoul, South Korea
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PubMed | National University, Gyeongnam National University of Science and Technology and Sunjin Co.
Type: | Journal: Journal of animal science and technology | Year: 2015

The study was performed to investigate the effect of dietary supplementation of a lipid-encapsulated Zinc oxide on growth parameters and intestinal mucosal morphology piglets born to Duroc-sired LandraceYorkshire dams. Twenty-four 30-day-old piglets weaned at 25days of age were orally challenged with 510(8) colony forming units of enterotoxigenic Escherichia coli (ETEC) K88 and fed one of the four diets for 7days: (i) a nursery basal diet containing 100-ppm ZnO (referred to as BASAL), (ii) BASAL supplemented with 120-ppm apramycin (referred to as ANTIBIO), (iii) BASAL with 2,400-ppm ZnO (referred to as HIGH), and BASAL containing 100-ppm lipid-encapsulated ZnO (referred to as LE). All piglets were killed at the end of the experiment for histological examination on the intestine. The results showed that the average daily gain (ADG), the villus height: crypt depth (CD) ratio in the ileum, and the goblet cell density of the villus and crypt in the duodenum, jejunum, and colon were greater in the LE-fed group that those of the BASAL (p<0.05). Fecal consistency score (FCS) and the CD ratio in the ileum were less in the LE-fed group, compared to the BASAL-fed one (p<0.05). The effects observed in the LE-fed group were almost equal to those of the HIGH-fed group as well as even superior to those of the ANTIBIO-fed group. Taken together, our results imply that dietary supplementation of 100-ppm lipid-encapsulated ZnO is as effective as that of 2,400-ppm ZnO for promoting growth diarrhea and intestinal morphology caused by ETEC infection.


Park B.C.,Sunjin Co. | Jung D.Y.,Gyeongnam National University of Science and Technology | Kang S.Y.,Gyeongnam National University of Science and Technology | Ko Y.H.,Gyeongnam National University of Science and Technology | And 6 more authors.
Animal Feed Science and Technology | Year: 2015

The present experiment was performed to investigate the effects of a lipid-encapsulated ZnO product (Shield Zn) on growth, intestinal morphology, and digestive enzyme activities in (Yorkshire. ×. Landrace). ×. Duroc piglets. A total of 408 21-day-old weanling pigs were allotted by sex and body weight to 12 pens, with 34 animals per pen, in a randomized complete block design. The animals were fed a ZnO-free basal nursery diet supplemented with 125. mg ZnO (100. mg Zn)/kg (ZnO-100), 3125. mg ZnO/kg (ZnO-2500), or 139. mg of lipid-encapsulated Shield Zn (100. mg Zn)/kg (Shield Zn-100) for 14 days, after which 24 animals were killed for examination of intestinal morphology and digestive enzyme activities. The average daily gain of the Shield Zn-100 group (207. g/d) was greater (P<0.01) than that of the ZnO-100 group (184. g/d), but was less (P<0.01) than that of the ZnO-2500 group (235. g/d). The average daily feed intake was less in the Shield Zn-100 (326. g/d) than in the Zn-2500 group (367. g/d; P<0.01), not being different between the former and the ZnO-100 group (309. g/d; P=0.23). However, the gain:feed ratio was not influenced by the treatment. The fecal consistency (diarrhea) score subjectively measured by a 3-notch integer scale was greater (P<0.01) in the Shield Zn-100 (1.30) and ZnO-100 (1.31) groups vs. ZnO-2500 group (1.06). Hepatic and circulating Zn concentrations were less (P<0.01) in the Shield Zn-100 and ZnO-100 groups vs. ZnO-2500, not being different between the former two groups. The villus height, crypt depth and villus height:crypt depth ratio in the duodenum, jejunum, and ileum as well as specific activities of sucrase, maltase, leucine aminopeptidase in these intestinal regions and amylase and trypsin activities in the pancreas were not influenced by the dietary treatment. In conclusion, the present results indicate that supplementation of Shield Zn at a physiological level is superior to that of native ZnO at the same level in supporting weight gain of weanling pigs, but that the former is inferior to pharmacological ZnO in the growth-enhancing and diarrhea-suppressing effects. © 2014 Elsevier B.V.


Kwon C.-H.,Kangwon National University | Lee C.Y.,Gyeongnam National University of Science and Technology | Han S.-J.,Kangwon National University | Kim S.-J.,Kangwon National University | And 3 more authors.
Animal Science Journal | Year: 2014

This study was aimed to evaluate the effect of dietary supplementation of lipid-encapsulated (coated) zinc oxide ZnO on post-weaning diarrhea (colibacillosis) in weaned piglets challenged with enterotoxigenic Escherichia coli (ETEC). Thirty-two 35-day-old weaned piglets were orally challenged with 3×1010 colony forming units of ETEC K88 while eight piglets received no challenge (control). Each eight challenged piglets received a diet containing 100ppm ZnO (low ZnO), 2500ppm ZnO (high ZnO) or 100ppm of lipid (10%)-coated ZnO (coated ZnO) for 7 days; control pigs received the low ZnO diet. Daily gain, goblet cell density in the villi of the duodenum, jejunum and ileum, and villus height in the jejunum and ileum, which decreased due to the challenge, were equally greater in the coated ZnO and high ZnO groups versus low ZnO group. Fecal consistency score, serum interleukin-8 concentration, subjective score of fecal E.coli shedding, and digesta pH in the stomach, jejunum and ileum, which increased due to the challenge, were equally low in the coated ZnO and high ZnO groups versus low ZnO. Results suggest that a low level of coated ZnO might well substitute for a pharmacological level of native ZnO in dietary supplementation to alleviate colibacillosis of weaned piglets. © 2014 Japanese Society of Animal Science.


Park B.-C.,Sunjin Co. | Ha D.-M.,Gyeongnam National University of Science and Technology | Park M.-J.,Gyeongnam National University of Science and Technology | Lee C.Y.,Gyeongnam National University of Science and Technology
Animal Science Journal | Year: 2014

This study was aimed at investigating the long-term effects of provision of liquid milk replacer (MR) and solid starter diet (SD) during lactation on post-weaning (PW) growth of pigs. In experiment 1, 33 cross-bred litters were allotted to four treatments: no supplement (CON), MR ad libitum, SD ad libitum and 100 g SD/litter/day from lactation day 4 through weaning at day 21 during late fall. In experiment 2, 40 litters received MR or none in July. PW pigs received commercial diets to marketing. In experiment 1, weaning weight (WW), pre-weaning average daily gain (ADG) and mortality (2.4%) were not influenced by creep-feeding MR or SD. ADG was greater (P < 0.05) in the MR group versus CON during days 21-54, but did not differ across the treatments during days 54-162. In experiment 2, ADG during lactation and WW were greater in the MR group versus CON, with mortality lower in the former (5.6 vs. 10.3%). However, PW ADG to day 175 did not differ between the two groups. Results suggest that creep-feeding MR or SD has no effect on PW growth. However, it remains possible that MR reduces PW mortality during the hot season. © 2014 Japanese Society of Animal Science.


PubMed | Gyeongnam National University of Science and Technology and Sunjin Co.
Type: | Journal: Journal of animal science and technology | Year: 2015

The present study was performed to investigate the effects of two groups of sires with medium and high weight gain potentials (M-sires and H-sires, respectively) on growth of their progenies on varying planes of nutrition during the growing-finishing period. The ADG of the M-sires progeny was greater (P<0.05) than that of the H-sires progeny (0.51 vs. 0.47kg) during a 26- to 29-d early grower phase beginning from 55 d of age, but the opposite was true (0.66 vs. 0.72kg) during the latter grower phase. Overall grower-phase ADG was greatest on the high plane of nutrition (H plane) followed by the medium (M) and low (L) planes (0.65, 0.61, and 0.51kg, respectively; P<0.05) in the M-sires progeny, whereas in the H-sires progeny, ADG was greater on the H and M planes vs. L plane (0.63, 0.62, and 0.54kg, respectively). The ADG of pigs on the M or H plane during the grower phase and switched to the H plane thereafter (M-to-H or H-to-H planes) was greater than that of pigs on the L-to-L planes (0.99 vs. 0.78kg) during the early finisher phase in the M-sires progeny (P<0.01). However, in the H-sires progeny, ADG of pigs on the L-to-L planes did not differ from that of pigs on the M-to-M or H-to-M planes (0.94 vs. 0.96kg). Results suggest that the H-to-H or H-to-M planes and M-to-M or M-to-L planes are optimal for maximal growth of the M- and H-sires progenies, respectively.


PubMed | Kangwon National University, Gyeongnam National University of Science and Technology and Sunjin Co.
Type: | Journal: Journal of animal science and technology | Year: 2015

This study compared the effects of varying lipid content and dietary concentration of a lipid-encapsulated (LE) ZnO product to those of native ZnO and thereby to find insights into optimal lipid coating and dosage of the Zn supplement. A total of 192 21-d-old weanling pigs were allotted to 48 pens, after which each six pens received a ZnO-free basal diet supplemented with 125ppm ZnO (100ppm Zn; BASAL), 2,500ppm Zn as native ZnO (HIGH), or 100 or 200ppm Zn as LE ZnO (LE-100 or LE-250) containing 8%, 10%, or 12% lipid [LE-8%, LE-10%, or LE-12%, respectively; 23 factorial arrangement within the LE-ZnO diets (LE-ALL)] for 14 d. Forty pigs were killed at the end for histological and biochemical examinations. None of ADG, ADFI, gain:feed, and fecal consistency score differed between the LE-ALL and either of the BASAL and HIGH groups. Hepatic and serum Zn concentrations were greater (p <0.05) in the HIGH vs. LE-ALL group, but did not differ between LE-ALL and BASAL, between LE-100 and -250, or among LE-8%, -10%, and -12% groups. Villus height (VH), crypt depth (CD), and the VH:CD ratio in the duodenum, jejunum, and ileum did not differ between the LE-ALL and either of the BASAL and HIGH groups, except for a greater CD in the duodenum in the LE-ALL vs. HIGH group. Additionally, VH and CD in the duodenum and VH:CD in the jejunum were greater in the LE-250 vs. LE-100 group. Specific activities of sucrase, maltase, and leucine aminopeptidase in these intestinal regions and those of amylase and trypsin in the pancreas were not influenced by the lipid content or dietary concentration of LE ZnO and also did not differ between the LE-ALL and either of the BASAL and HIGH groups, except for a greater pancreatic amylase activity in the former vs. HIGH group. In conclusion, the present results indicate that the LE ZnO, regardless of its lipid percentage or supplementation level examined in this study, has no significant effect on growth performance, fecal consistency, or digestive enzyme activities of weanling pigs under the experimental conditions.


Choe J.H.,Korean University of Science and Technology | Choe J.H.,Korea University | Choi M.H.,Korean University of Science and Technology | Ryu Y.C.,Jeju National University | And 10 more authors.
Animal Production Science | Year: 2015

The objectives of this study were to investigate the correlations between various blood parameters compared with cortisol and lactate levels under the standard pre-slaughter procedure and handling conditions and to assess their potential as indicators of pork quality traits. Despite there being no additional pre-slaughter stress treatment, there is considerable variation in blood parameters at exsanguination. Serum cortisol and blood lactate levels, widely used indicators of stress, were positively correlated with blood glucose and electrolytes, such as calcium, potassium and sodium. Moreover, these parameters were significantly correlated with a rapid rate of early postmortem glycolysis and reduced water-holding capacity. In particular, blood lactate and glucose levels significantly differed between porcine quality classes. However, other blood parameters including electrolytes did not significantly differ between quality classes though they significantly correlated with pork quality traits. Therefore, serum cortisol, blood lactate and glucose have potential as indicators of the rate and extent of postmortem metabolism and ultimate pork quality under the standard procedure and handling conditions of pre-slaughter. © CSIRO 2015.

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