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Taneja V.,Subharti Medical College and Hospital | Taneja M.K.,Indian Institute of Ear Diseases
Indian Journal of Otology | Year: 2014

Ceruminous adenoma is a rare neoplasm of the external auditory meatus (EAM) with benign clinical behavior. They demonstrate a dual cell population of basal myoepithelial-type cells and luminal ceruminous cells. Cerumen pigment, cytokeratin 7 (CK7) and p63 can help to distinguish this tumor from other neoplasms that occur in the region. Complete surgical excision results in an excellent long-term clinical outcome. We present a case of histologically confirmed ceruminous adenoma of the EAM in a surgically treated 38-year-old female. She presented with recurrent serosanguineous discharge along with flakes from the right ear along with hearing impairment. She is doing well in last 8 months follow-up. Source


Mattoo K.A.,Subharti Dental College | Kumar S.,DJ Dental College and Hospital | Budhiraja V.,Subharti Medical College and Hospital
Indian Journal of Forensic Medicine and Toxicology | Year: 2011

The paper describes a simple procedure of facial reconstruction for forensic and other purposes utilizing tissue thickness determined from a cadaver of the same average age, body weight, race and ethnic origin. The technique reconstructs the face by making of an impression of the skull which is later poured with high strength gypsum. The thickness of the facial tissues is determined by measurements that were taken on a cadaver of same sex, age, ethnicity, body weight and origin. The muscles of the face were built using clay and then the clay model was refined by using the same clay of different consistency. A digital photograph is taken of the model which later serves as a 2- dimensional sketch for identification. Source


Sharma A.,Subharti Dental College and Hospital | Nagtilak S.,Subharti Medical College and Hospital | Khattak B.P.,Subharti Dental College and Hospital | Singh G.,LLRM Medical College | Bano T.,LLRM Medical College
International Journal of Pharma and Bio Sciences | Year: 2015

The purpose of the present study was to evaluate and compare the effect of nonsurgical periodontal therapy on salivary proteins in subjects with periodontitis and compare it with healthy subjects. A total of 30 subjects in age group between 30 and 45 years were enrolled, of which 15 had generalized severe Chronic Periodontitis (CP), and 15 periodontally healthy as a control (C). The clinical parameters included Plaque index (PI), Gingival index (GI), Pocket probing depth (PPD) Bleeding on probing (BOP) and Clinical attachment loss (CAL). Paraffin wax stimulated whole saliva was collected and immediately centrifuged at -4°C, assayed for salivary protein content using the Biuret Bicinchonic Acid protein assay reagent (BCA Kit)., both at baseline and at 4 week following scaling and root planing. Salivary proteins were significantly higher in Generalized Chronic Periodontitis subjects (p<0.05) as compared to control. After one month of scaling and root planing the salivary protein concentration between pre and post-periodontal therapy improved significantly (p<0.05).Subjects with established periodontitis exhibited elevated concentrations of salivary protein, suggesting that monitoring for change in salivary composition may be useful tool to establish favorable response to periodontal therapy. Source


Kannan S.,Subharti Medical College and Hospital | Gowri S.,Subharti Dental College | Tyagi V.,Subharti Medical College and Hospital | Kohli S.,Subharti Medical College and Hospital | And 3 more authors.
International Journal of Risk and Safety in Medicine | Year: 2015

BACKGROUND: Direct to physician advertisements and direct to consumer advertisement (DTCA) is a well-known marketing strategy of pharmaceutical companies. Studies from the West and also from the Indian sub-continent revealed several lacunae in such advertisements. OBJECTIVES: The present study was carried out to understand the international and national scenario regarding the lacunae in drug advertisements and the opinion of both physicians and patients regarding DTCA. METHODS: The present study was conducted after obtaining approval from the institutional ethics committee. Warning letters (WLs) issued to pharmaceutical companies by United States Food and Drug Administration (USFDA) and Therapeutic Goods Administration (TGA) due to discrepancies in the advertisements were analyzed for reasons that were grouped into one of the following categories: overstatement of efficacy; unapproved indication; lack of adequate directions to use; omission of adverse effects; misleading claims; advertisement made for an unapproved drug (investigational new product). Drug advertisements in Current Index of Medical Specialties (CIMS) April-July 2014 issue was also analyzed for lacunae depending on categories as mentioned above. Physicians and patients in a tertiary care medical college and hospital were administered a validated questionnaire exploring their views about crucial aspects of DTCA. Descriptive statistics was used for each of the categories. RESULTS: A total of 93 WLs issued by USFDA and 36 by TGA were assessed. Majority of the WLs by USFDA were issued for omission of adverse effects (61/93, 65.6%) followed by misleading claims (54/93, 58.1%). Similarly, WLs by TGA were also mainly issued for the presence of misleading claims (35/36, 97.2%) followed by overstatement of efficacy (26/36, 72.2%) and CIMS evaluation had revealed that 78/92 (84.8%) advertisements omitted adverse effects, 20/92 (21.7%) had misleading claims, 9/92 (9.8%) had unapproved indications and 7/92 (7.6%) overstated the efficacy. With regard to the opinion regarding DTCA, 69.9% physicians had a patient discussing DTCA that was clinically inappropriate. One hundred (64.5%) out of 155 physicians opined that DTCA encourage patients to attend physicians regarding preventive healthcare. On the contrary, 82/155 (52.9%) physicians felt that DTCA would damage the same. Similarly, 69 out of the total 100 patients felt that drug advertisements aid them to have better discussions with their treating physicians. Surprisingly, a large majority (91/100) were of the opinion that only safe drugs are allowed to be advertised. CONCLUSION: To conclude, from the findings of this study both the physicians and patients should be cautious and not overzealous while dealing with drug advertisements or promotional literature. More stringent scrutiny and issue of WLs or blacklisting of indulging pharmaceutical companies are mandatory by the regulatory agency to contain the same. © 2015 - IOS Press and the authors. All rights reserved. Source


Arora A.,Subharti Medical College and Hospital | Kannan S.,Subharti Medical College and Hospital | Kannan S.,Fiji National University | Gowri S.,Subharti Dental College | And 4 more authors.
Indian Journal of Medical Research | Year: 2016

Background & objectives: Substance abuse is found worldwide including among students. We carried out this study to estimate the prevalence of substance abuse among medical student studying in a medical college in north India. Methods: Using a validated questionnaire a cross-sectional survey was conducted among 230 undergraduate and postgraduate medical students in a private medical college. Results: The prevalence of substance abuse was 20.43 per cent (47/230) among medical students. An increase in substance abuse was observed in the latter years of medical education. A total of 43 of 47 (91.7%) students using these substances were aware of the ill effects. The most common reasons for substance use were relief from psychological stress (34/47, 72.4%) and occasional celebration (34/47, 72.4%). Of the 47 substance users, 28 (59.6%) made past attempts to quit the substance abuse. Interpretation & conclusions: Nearly one-fifth of medical students abuse at least one substance despite knowing the ill effects with the main predisposing factor being the psychological stress. © 2016, Indian Council of Medical Research. All rights reserved. Source

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