Student Research Center

Iran

Student Research Center

Iran

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Anvari F.,Student Research Center | Dabagh-Gorjani F.,Student Research Center | Soltani-Zangbar M.-S.,Student Research Center | Kamali-Sarvestani E.,Autoimmune Diseases Research Center | And 3 more authors.
Iranian Journal of Immunology | Year: 2015

Background: Pre-eclampsia (PE) is one of the most important and life-threatening pregnancy disorders that affect at least 3-5% of all pregnancies. Imbalance in helper T cell functions may play a role in predisposing to PE or severity of the disease. Elevated frequencies of Th17 cells in the peripheral blood of PE patients have been reported. Several single nucleotide polymorphisms (SNP) within IL-17 gene have been identified that may affect the IL-17 production. Objectives: To investigate the association between IL-17A (-197A/G) and IL-17F (+7488T/C) gene polymorphisms and susceptibility to PE in a group of Iranian women. Moreover, to study any correlation of the polymorphisms data with the level of IL-17, at mRNA level in the paternal and maternal parts of the placentas and also at protein level in the peripheral and placental blood samples. Methods: A group of 261 PE patients and 278 age-matched healthy women with at least two previous normal pregnancies formed the cases and controls of this study. IL-17A (-197A/G) and IL-17F (+7488T/C) polymorphisms were genotyped using PCR-RFLP method. The protein level of IL-17A was assessed in the sera of 40 PE and 40 healthy women using ELISA method and mRNA expression was also measured in placental samples of 19 PE and 19 control women using Q-PCR technique. Results: Statistical analysis indicated that there were no differences in genotype, allele or haplotype frequencies regarding the studied SNPs between cases and controls. The level of IL-17A was elevated in the placental blood and the fetal tissue at protein and mRNA levels (p< 0.009 and p<0.000, respectively) in PE as compared with the healthy women. Conclusions: The effect of IL-17 cytokine in pre-eclampsia is not due to the studied cytokine polymorphisms but local production of IL-17 might have an effect on the predisposition to the disease. © 2015, Shiraz University of Medical Sciences. All rights reserved.


Hasanlu M.R.,Islamic Azad University at Zanjan | Asadian F.,Islamic Azad University at Tehran | Arzjani Z.,Student Research Center | Khalafi J.,Agricultural and Natural Resources Research Center of Iran
Life Science Journal | Year: 2013

There are a number of elements impacting the expansion of current groundwater resources, including the role of structural operators viz. faults, seams and gaps, lithological agents among them are the structure of region and topographical elements like the slope and the height of the area in question. Geomorphologic processes and forms are among the most important elements controlling the supply, direction of flow, quality and quantity of groundwater resources and have a serious impact on them. For this reason, in current research, incorporating field studies with remote sensing (RS) we embark providing different maps of affecting factors on groundwater resources and finally incorporating them in Graphic Information System (GIS) which leads to geomorphic map of Saremsaghloo-Gharecharyan map in the Zanjan province. Afterwards, the figures and phenomena obtained are used as a ground for comparison and evaluation of their relationships with groundwater resources in question. According to the conclusions obtained from current research, there is a close relation between geomorphologic phenomena and groundwater resources which shows the possibility of using geomorphologic phenomena for locating groundwater resources. One can mention, according to these facts that plain's north highlands, floodplains, alluvial terraces and alluvial fans are among the most influential elements affecting groundwater resources. On the basis of relation between geomorphologic phenomena and groundwater resources, those regions capable of groundwater resources were diagnosed. After that, a number of suggestions have been putted forward for reinforcing and improving the Saremsaghloo plain, like locating appropriate places for artificial feeding of groundwater resources and constructing underground dams in those areas having groundwater and proper context.


PubMed | Isfahan University of Medical Sciences, Student Research Center and Nursing and Midwifery Care Research Center
Type: Journal Article | Journal: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit | Year: 2016

This qualitative study in the Islamic Republic of Iran aimed to explore facilitators and barriers to the use of reproductive health services by unmarried women. A purposive sample of unmarried women aged 25-60 years in Isfahan city were interviewed about their experiences of reproductive health services in public health centres. Content analysis of responses revealed that the favourable characteristics of reproductive health services in public centres were services that: were delivered by personnel of the same sex in a woman-friendly environment and available at a suitable price, and did not label clients. In contrast, the following characteristics made public health centres undesirable for unmarried women: not addressing single women for reproductive health services; lack of privacy; failure to maintain confidentiality; doubts about skills and scientific ability of personnel; and lack of integration of services.


Goli A.,Shiraz University | Kermany F.S.,Student Research Center | Askarian M.,Anesthesiology and Critical Care Research Center
International Journal of Preventive Medicine | Year: 2014

Background: Although intellectual disability (ID) is a common disability in Iran, there is no investigation on the spatial distribution pattern of these patients in national level and the spatial maps for recognition the areas with higher prevalence of IDs and local neighborhoods of these regions or effect of socio-demographic factor on this scattering is not still available. This proposition motivated us to assess the population with ID in our country. Methods: In a cross-sectional study, we applied Moran's Index (Moran's I) which includes information about the strength of the neighboring association between counties, as global univariate distribution assessment. A geographically weighted regression was used to explore relation between ID patient's prevalence and some socio-demographic factors (migration and illiteracy rate, physician number (PN)/10,000 people and health-care centers (HCCs)/10,000 people). Results: We found that spatial clusters of ID patients exist among Iran counties (Moran's I = 0.36, P < 0.01) and in a rural area population groups (Moran's I = 0.20, P < 0.01). Further, we detected spatial associations between ID patients and all of our investigated socio-demographic factors in national scale. In rural areas, illiteracy has high association with ID especially in the south region of Iran. Urban area has random pattern of ID patients both within and between the Iran counties (Moran's I = 0.01, P > 0.3). Conclusions: According to the results, our Initial hypothesis about the existence of spatial clusters in distribution of people with ID in Iran was proven. Spatial autocorrelation between migration and illiteracy rate and prevalence of patients with ID was shown and was in agreement with our hypothesis. However, our supposition that the prevalence should have inverse relationship with PN and HCC was rejected.


Ebrahimi A.,University of Yazd | Taheri E.,Isfahan University of Medical Sciences | Taheri E.,Student Research Center | Ehrampoush M.H.,University of Yazd | And 5 more authors.
Journal of Environmental and Public Health | Year: 2013

The treatment of municipal wastewater from Yazd city (center of Iran) by constructed wetland vegetated with Cyperus alternifolius was assessed. Two identical wetlands with a total working volume of 60 L and 10 cm sandy layer at the bottom were used. First wetland (W1) was control and had no Cyperus alternifolius plant. Second wetland (W2) had 100 Cyperus alternifolius shrubs with 40 cm height. Influent wastewater was provided from Yazd's septic tanks effluents and after a 4-day retention time in wetlands, reactors effluent was sampled for parameters analysis. Results show that chemical oxygen demand (COD), N O 3 - -N, N H 4 + -N, and P O 4 - 3 -P in W1 were reduced to 72%, 88%, 32%, and 0.8%, and in W2, these parameters were removed in values of 83%, 81%, 47%, and 10%, respectively. In both wetlands, the highest and lowest removal efficiencies were related to COD and phosphorus, respectively. Also, the removed phosphorus can be released to stream when the soil saturated or influent phosphorus decreased and when the plant died. After a 4-day-retention time, the W2 wetland showed a statistically significantly lower COD and N H 4 + -N in comparison with W2 wetland. © 2013 Asghar Ebrahimi et al.


Amin M.M.,Isfahan University of Medical Sciences | Khiadani (Hajian) M.H.,Isfahan University of Medical Sciences | Khiadani (Hajian) M.H.,Edith Cowan University | Fatehizadeh A.,Isfahan University of Medical Sciences | And 3 more authors.
Desalination | Year: 2014

Microbial characteristics and behavior were undertaken for the treatment of synthetic saline wastewater. Two sequencing batch reactor (SBR) with non-adapted and adapted inoculum (SBR1, SBR2) to saline wastewater and various initial NaCl and chemical oxygen demand (COD) concentrations were operated. In both SBRs, the initial COD of influent wastewater was gradually progressed to 3000mg/L, whereas NaCl content increased up to 10,000mg/L. The average of COD reduction in SBR1 and SBR2 was obtained 96 and 95%, respectively. The kinetic modeling showed that the experimental data from saline wastewater treatment by SBRs were fitted well to the Grau second order kinetic model (R2: 0.99). Model evaluation was then carried out by calculating the linearity between the observed data and predicted values. The result confirmed that in comparison with First and Grau second-order kinetic models, the Monod and Contois models were not suitable in solid retention time (SRT)<4d. As SBRs operated at SRT>4d, the salinity can cause lower fluctuation in SBR efficiency. Among the non-linear kinetic models, the Grau second-order model gave a better description of the substrate consumption than the typical Monod, Contois and First order model for the saline wastewater treatment in this study. © 2014 Elsevier B.V.

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