Agency: Cordis | Branch: FP7 | Program: CP-IP | Phase: NMP.2010.2.3-1 | Award Amount: 14.80M | Year: 2012
The development of functional materials for tissue regeneration is today mostly based on perceived and limited design criteria often using a single point approach with lengthy animal trials. The outcome after in-vitro and in-vivo evaluation is often disappointing resulting in a tedious iteration process. The main objective of this project is to achieve radical innovations in state-of-the-art biomaterials and to design highly performing bioinspired materials learning from natural processes. By this outcome driven project comprising first class academic and industrial participants the project will create scientific and technical excellence and through links with these SMEs will strengthen the technological capacity and their ability to operate competitively on an international market. BIODESIGN will (i) perform a careful retrospective-analysis of previous outcomes from clinical studies performed with humans through animal modelling in a reverse engineering approach applied to an in-vitro to the molecular design level, (ii) develop new strategies for a more rational design of ECM mimetic materials serving both as gels and load carrying scaffolds, (iii) link novel designs to adequate and more predictive in-vitro methods allowing significant reduction in development time and use of animals and (iv) evaluate these concepts for musculoskeletal and cardiac regeneration. By the development of safe, ethically and regulatory acceptable, and clinically applicable materials this project will promote harmonization while at the same time creating awareness in society of the benefits of these innovations as one of the key points is to improve health and quality of life of the patients. BIODESIGN will stimulate technological innovation, utilization of research results, transfer of knowledge and technologies and creation of technology based business in Europe. It will also support the development of world-class human resources, making Europe a more attractive to top researchers.
Stryker Trauma SA | Date: 2014-05-14
A system and method for pressing fragments of a fracture against each other are provided. The system includes a compression device comprising a hollow shaft, wherein an inner engagement portion for engaging an outer feature of a screw head is arranged at a distal end of the shaft, a supporting element with a contact surface adapted to abut on one of the fragments, and a joint between the supporting element and the hollow shaft. The joint is formed so as to allow a rotation of the shaft about a longitudinal axis thereof relative to the supporting element. Additionally, the joint is formed to allow a pivot movement of the supporting element relative to the shaft.
Stryker Trauma Gmbh | Date: 2014-02-18
A method and a device are provided, for measuring an actual length of a fractured bone based on 2D fluoroscopic images of proximal and distal sections of the bone, each of the images including a reference body. Based on the images, a spatial position of a first end point and a spatial position of a second end point are determined, taking into account dimensions taken from a bone model of a bone corresponding to the imaged bone and the spatial positions of the reference bodies. The actual length of the fractured bone is defined as the distance between the two end points.
Stryker Trauma GmbH | Date: 2014-12-10
A sleeve clamp is proposed comprising a body with a through bore for receiving a sleeve, and a clamping element. The clamping element includes a clamping edge and may be arranged at the body so as to be movable between two positions, i.e. a neutral position and a deflected position. In the neural position, the clamping edge protrudes laterally into a lumen which is occupied by the sleeve when the sleeve is received in the through bore. In the deflected position, the clamping element may be elastically deformed and the clamping edge does not protrude into the lumen which is occupied by the sleeve when the sleeve is received in the through bore.
Stryker Trauma AG | Date: 2014-03-12
A system for bending a surgical device is disclosed in which the system may include a bending apparatus having a housing with a series of posts received therein. In some embodiments, one of the series of posts may be selectively movable within an elongate slot in the housing, while another of the series of posts may be radially movable. Movement of the radially movable post may serve to bend a surgical device about at least one of the other remaining posts. A tool may also be provided with the system for interacting with a lever and causing the radially movable post to move radially. An alternate apparatus for bending a surgical device is also disclosed, as are methods of bending a surgical device using the aforementioned system.
Stryker Trauma GmbH | Date: 2014-02-04
In one embodiment, the present invention is a method of fusing fractures of a femoral neck using a bone plate including the steps of: placing a bone plate on the femur; inserting an assembly of a bone screw and a locking ring in an opening in the plate; simultaneously threading the locking ring and the bone screw in the femur; threading the bone screw in the femur to compress the fracture; creating a space between the locking ring and the bone screw; and allowing the bone screw to move towards the locking ring when the femur is loaded. In another embodiment, the present invention is a bone plating system including a bone plate having a plurality of openings; at least one bone screw capable of being received through the opening and into a bone; at least one end cap fixedly insertable in the opening; and a layer of polymeric material interposed between the end cap and the top of the head.
Stryker Trauma Sa | Date: 2014-01-16
A locking peg includes a head and a shaft. The head is at the proximal end of the locking peg, and a shaft extends distally from the head to a distal end of the locking peg. The shaft has a threaded proximal portion and an unthreaded distal portion. A length of the unthreaded distal portion of the shaft is greater than a length of the threaded proximal portion of the shaft. When the locking peg is inserted into a bone through a bone plate, the threaded proximal portion of the shaft extends into the bone. This extended threading provides additional axial force to help explant the locking peg during removal of the locking peg.
Stryker Trauma GmbH | Date: 2014-08-20
The present disclosure relates to software used in planning the correction of bone deformities preoperatively or postoperatively, and in particular relates to virtually manipulating rings (305, 310) and struts of an external fixation frame in order to plan the steps for making a desired correction to two or more bone portions of a patient. The software can be used prior to surgery, allowing a user to virtually define a bone deformity, and virtually add and manipulate fixation rings and struts to the bone deformity. Based on the virtual manipulations, a correction plan (510) can be generated that describes length adjustments that should be made to the plurality of model struts over a period of time to correct the bone deformity. The software can also be used after surgical fixation of the fixation frame and struts to the deformed bone.
Stryker Trauma SA | Date: 2014-09-10
An external fixation system has a planar ring (102) with an adjustable device (800, 900) having a body (802, 902) releasably mounted on the ring. The adjustable device includes a first member (806, 906) for movement in a direction generally perpendicular to the ring. A second member (808A, 908A) is mounted on the first member for movement in a direction parallel to a side wall of the planar ring. A method for treating a broken bone includes providing an external fixation system and inserting a bone fastener through a first bone piece and affixing the first bone fastener to the ring, then inserting a second bone fastener through a second bone piece and affixing the second bone fastener to the adjustable device. The pieces of bone are realigned, compressed, or distracted by adjusting at least one of the first and second adjustable members.
Stryker Trauma SA | Date: 2015-10-28
An external fixation frame for correcting a bone deformity includes a first fixation ring (101) and a second fixation ring (102). Medial and lateral adjustable length struts (103b) couple medial and lateral portions of the first fixation ring (101) to medial and lateral portions of the second fixation ring (102) respectively. The fixation frame also includes a half ring (113) hingedly coupled to the second fixation ring.