Stryker Orthopedics

Luimneach, Ireland

Stryker Orthopedics

Luimneach, Ireland

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Enterprise mobility continues to serve as a driving force in boosting company productivity and flexibility. The ubiquity of mobile devices ensures that the business apps running on them can reach large-scale audiences and address an array of organizational needs. This driving force will only increase as wearables and the Internet of Things (IoT) become more mainstream. SEE: Mobile has officially passed desktop as the top source of web traffic worldwide It's a common trend now for employees to choose the business apps they feel best meet their needs, and this in turn challenges enterprises to produce mobile apps to solve these needs. With that trend in mind, Adobe conducted a recent survey to examine the state of mobile apps in the enterprise, with a focus on the opportunities for organizations seeking to leverage apps to stoke productivity and remain competitive. The survey was based on input from managers in the HR, sales, and marketing fields across five countries (the United States, Germany, the United Kingdom, China and India). Here are some key insights from the survey: In the last year, the number of employees using enterprise mobile apps and the number of apps themselves is increasing. Investment in enterprise mobile apps is on the rise 56% of respondents expect their enterprise mobile apps investment to increase next year and 66% have the same expectation for the next three years. In addition, it's worth pointing out that companies are seeing a 35% ROI in their mobile app investments, on average. Enterprise mobile apps deliver competitive advantage, but companies haven't brought their strategies in-line to compete Employees were asked what risks their organizations faced without the use of enterprise mobile apps. 61% of respondents believe that companies risk being at a competitive disadvantage by not embracing mobile apps due to less efficient operations, looking outdated (51%) and missing out on new clients or sales (47%). However, when it comes to besting their competitors with an enterprise mobile app strategy, 62% feel this was a priority, but only 34% consider themselves they were ahead of the curve. The remaining two-thirds of respondents believe their department is just on-par, or behind their competitors. Mobile apps will become even more mission critical Messaging and collaboration systems, "customer service and support, and customer relationship management were deemed the three most critical categories for competitive advantage. All categories had a strong measure of relevance, however, with the lowest-ranked choice, employee onboarding and benefits, still picked by over a third of respondents. Expectations for change in the enterprise mobile app industry over the next year Survey respondents predicted that the mobile industry will increase its focus on security, cloud-driven apps and user experience in the next year. "Companies are increasingly equipping their employees for productivity with enterprise mobile apps. For example, global science company DuPont uses apps to deliver product content to its sales force. DuPont provides a huge amount of technical content across 130 countries, and centralized apps powered by Adobe Experience Manager (AEM) Mobile have resulted in $1 million in savings. And they're not alone in their success with apps using AEM Mobile: Hartford Funds engages its financial advisors with market-oriented app content, Stryker Orthopedics has saved $3.9 million by converting print sales enablement to apps, and Celebrity Cruises has reduced sales quote prep time by 40 percent using mobile sales tools." The depth and breadth of enterprise mobile apps will continue to grow as these programs evolve to meet business needs. Themes of security/privacy protection, cloud computing and a strong user experience (UI) will be prevalent. The strategies outlined herein can help establish the difference between a stagnant, backward-facing approach or a nimble, productive outlook in the mobile app realm. Also see: Five reasons people hate your mobile app Report: Android and iOS apps both leak private data, but one is definitely worse for the enterprise IBM Watson is coming to the iPhone, and that's big news for business users How Mendix' Smart Apps help large companies innovate like startups Apps vs. mobile websites: Which option offers users more privacy?


Pierce T.P.,Rubin Institute for Advanced Orthopedics | Jauregui J.J.,Rubin Institute for Advanced Orthopedics | Cherian J.J.,Rubin Institute for Advanced Orthopedics | Elmallah R.D.K.,Rubin Institute for Advanced Orthopedics | And 2 more authors.
HIP International | Year: 2015

Purpose: Cementless press-fit total hip arthroplasty (THA) with the Accolade stem (Stryker Accolade™TMZF, Mahwah, New Jersey) has demonstrated variable implant survivorship and outcomes. The purpose of this study was to analyse the: 1) implant survivorship; 2) complications; 3) functional outcomes; 4) overall quality of life; and 5) patient expectations and satisfaction following THA with this particular press-fit stem. Methods: A prospectively collected database of 222 patients who underwent THA at 7 institutions between 2006 and 2009 using the Accolade stem (Stryker Inc. Mahwah, New Jersey) was evaluated. Harris Hip Score (HHS) and SF-12 were used to assess the outcomes at 2- and 5-year follow-up. Kaplan-Meier survivorship was calculated at 5 years of follow-up. Results: The 5-year aseptic and all-cause survivorship rates were 99.4% (95% CI, 96.3 to 99.9%) and 97.9% (95% CI, 94.6 to 99.2%), respectively. At 2 and 5 years postoperatively, the patients demonstrated a mean HHS of approximately 89 points and 92 points, respectively. The mental and physical components of the SF-12 mean score increased with the physical component having a more marked increase. The mental and physical components of the SF-12 score increased to a mean of 46 and 45 points at 2 and 5 years, respectively. At 2-year follow-up, over 90% of patients were satisfied with their outcome in a majority of areas surveyed. Discussion: Our results suggest that the use of this press-fit construct results in tremendous improvements in functional and quality of life outcomes, along with excellent survivorship at short- and mid-term follow-up. © 2015 Wichtig Publishing.


PubMed | Sinai Hospital of Baltimore, Stryker Orthopedics and Rubin Institute for Advanced Orthopedics
Type: Evaluation Studies | Journal: Hip international : the journal of clinical and experimental research on hip pathology and therapy | Year: 2015

Cementless press-fit total hip arthroplasty (THA) with the Accolade stem (Stryker AccoladeTM TMZF, Mahwah, New Jersey) has demonstrated variable implant survivorship and outcomes. The purpose of this study was to analyse the: 1) implant survivorship; 2) complications; 3) functional outcomes; 4) overall quality of life; and 5) patient expectations and satisfaction following THA with this particular press-fit stem.A prospectively collected database of 222 patients who underwent THA at 7 institutions between 2006 and 2009 using the Accolade stem (Stryker Inc. Mahwah, New Jersey) was evaluated. Harris Hip Score (HHS) and SF-12 were used to assess the outcomes at 2- and 5-year follow-up. Kaplan-Meier survivorship was calculated at 5 years of follow-up.The 5-year aseptic and all-cause survivorship rates were 99.4% (95% CI, 96.3 to 99.9%) and 97.9% (95% CI, 94.6 to 99.2%), respectively. At 2 and 5 years postoperatively, the patients demonstrated a mean HHS of approximately 89 points and 92 points, respectively. The mental and physical components of the SF-12 mean score increased with the physical component having a more marked increase. The mental and physical components of the SF-12 score increased to a mean of 46 and 45 points at 2 and 5 years, respectively. At 2-year follow-up, over 90% of patients were satisfied with their outcome in a majority of areas surveyed.Our results suggest that the use of this press-fit construct results in tremendous improvements in functional and quality of life outcomes, along with excellent survivorship at short- and mid-term follow-up.


Swaminathan V.,Syracuse University | Swaminathan V.,Syracuse Biomaterials Institute | Zeng H.,Stryker Orthopedics | Lawrynowicz D.,Stryker Orthopedics | And 3 more authors.
Electrochimica Acta | Year: 2012

This study investigated the electrochemical behavior of chromium nano-carbide cermet coating applied on Ti-6Al-4V and Co-Cr-Mo alloys for potential application as wear and corrosion resistant bearing surfaces. The cermet coating consisted of a highly heterogeneous combination of carbides embedded in a metal matrix. The main factors studied were the effect of substrate (Ti-6Al-4V vs. Co-Cr-Mo), solution conditions (physiological vs. 1 M H 2O 2 of pH 2), time of immersion (1 vs. 24 h) and post coating treatments (passivation and gamma sterilization). The coatings were produced with high velocity oxygen fuel (HVOF) thermal spray technique at atmospheric conditions to a thickness of 250 μm then ground and polished to a finished thickness of 100 μm and gamma sterilized. Native Ti-6Al-4V and Co-Cr-Mo alloys were used as controls. The corrosion behavior was evaluated using potentiodynamic polarization, mechanical abrasion and electrochemical impedance spectroscopy under physiologically representative test solution conditions (phosphate buffered saline, pH 7.4, 37°C) as well as harsh corrosion environments (pH ∼ 2, 1 M H 2O 2, T = 65°C). Severe environmental conditions were used to assess how susceptible coatings are to conditions that derive from possible crevice-like environments, and the presence of inflammatory species like H 2O 2. SEM analysis was performed on the coating surface and cross-section. The results show that the corrosion current values of the coatings (0.4-4 μA/cm 2) were in a range similar to Co-Cr-Mo alloy. The heterogeneous microstructure of the coating influenced the corrosion performance. It was observed that the coating impedances for all groups decreased significantly in aggressive environments compared with neutral and also dropped over exposure time. The low frequency impedances of coatings were lower than controls. Among the coated samples, passivated nanocarbide coating on Co-Cr-Mo alloy displayed the least corrosion resistance. However, all the coated materials demonstrated higher corrosion resistance to mechanical abrasion compared to the native alloys. © 2011 Elsevier Ltd. All Rights Reserved.


Swaminathan V.,Syracuse Biomaterials Institute | Zeng H.,Stryker Orthopedics | Lawrynowicz D.,Stryker Orthopedics | Zhang Z.,Stryker Orthopedics | Gilbert J.L.,Syracuse Biomaterials Institute
Journal of Biomedical Materials Research - Part B Applied Biomaterials | Year: 2011

Hard coatings for articulating surfaces of total joint replacements may improve the overall wear resistance. However, any coating approach must take account of changes in corrosion behavior. This preliminary assessment analyzes the corrosion kinetics, impedance and mechanical-electrochemical stability of 100 μm thick plasma sprayed chromium oxide (Cr 2O 3) coatings on bearing surfaces in comparison to the native alloy oxide films on Co-Cr-Mo and Ti-6Al-6V. Cyclic potentiodynamic polarization, electrochemical impedance spectroscopy, and mechanical abrasion under potentiostatic conditions were performed on coated and substrate surfaces in physiological saline. SEM analysis characterized the coating morphology. The results showed that the corrosion current density values of chromium oxide coatings (0.4-1.2 μA/cm 2) were of the same order of magnitude as Ti-6Al-4V alloy. Mechanical abrasion did not increase corrosion rates of chromium oxide coatings but did for uncoated Co-Cr-Mo and Ti-6Al-4V. The impedance response of chromium oxide coatings was very different than Co-Cr-Mo and Ti-6Al-4V native oxides characterized by a defected coating model. More of a frequency-independent purely resistive response was seen in mid-frequency range for the coatings (CPE coat: 40-280 nF/cm 2 (rad/s) 1-α, α: 0.67-0.83) whereas a more capacitive character is seen for Co-Cr-Mo and Ti-6Al-4V (CPE ox around 20 μF/cm 2 (rad/s) 1-α, α around 0.9). Pores, interparticle gaps and incomplete fusion typical for thermal spray coatings were present in these oxides which could have influenced corrosion resistance. The coating microstructure could have allowed some fluid penetration. Overall, these coatings appear to have suitable corrosion properties for wear surfaces © 2011 Wiley Periodicals, Inc.


Mullen L.,University of Liverpool | Stamp R.C.,University of Liverpool | Fox P.,University of Liverpool | Jones E.,Stryker Orthopedics | And 2 more authors.
Journal of Biomedical Materials Research - Part B Applied Biomaterials | Year: 2010

In this study, the unit cell approach, which has previously been demonstrated as a method of manufacturing porous components suitable for use as orthopedic implants, has been further developed to include randomized structures. These random structures may aid the bone in-growth process because of their similarity in appearance to trabecular bone and are shown to carry legacy properties that can be related back to the original unit cell on which they are ultimately based. In addition to this, it has been shown that randomization improves the mechanical properties of regular unit cell structures, resulting in anticipated improvements to both implant functionality and longevity. The study also evaluates the effect that a post process sinter cycle has on the components, outlines the improved mechanical properties that are attainable, and also the changes in both the macro and microstructure that occur. © 2009 Wiley Periodicals, Inc.


Bhimji S.,Stryker Orthopedics
The journal of knee surgery | Year: 2010

The objective of this study was to develop a novel method to quantify rotational micromotion of modular tibial components that incorporates physiologic loading conditions, a physiologic test environment, and constraint characteristics of the articulating surface. The methodology is reviewed and data are presented on four total knee designs. Results showed the design with a rotational stabilizing island to demonstrate the most capability in resisting rotational micromotion for a given reacted torque, followed by a full peripheral capture device, then a partial peripheral capture device, and then a full peripheral capture device with a posterior lipped edge. Under walking and stair-climbing loads, the full peripheral capture device imparts more torque to the insert than the other designs due to the higher constraint of its articulating surface and thus experiences the most micromotion. The rotational stabilizing island device reveals the least amount of motion, due to a combination of its locking mechanism and a less constrained articular surface.


Lewallen E.A.,Mayo Medical School | Jones D.L.,Mayo Medical School | Dudakovic A.,Mayo Medical School | Thaler R.,Mayo Medical School | And 8 more authors.
Gene | Year: 2016

Integration of porous metal prosthetics, which restore form and function of irreversibly damaged joints, into remaining healthy bone is critical for implant success. We investigated the biological properties of adipose-tissue-derived mesenchymal stromal/stem cells (AMSCs) and addressed their potential to alter the in vitro microenvironment of implants. We employed human AMSCs as a practical source for musculoskeletal applications because these cells can be obtained in large quantities, are multipotent, and have trophic paracrine functions. AMSCs were cultured on surgical-grade porous titanium disks as a model for orthopedic implants. We monitored cell/substrate attachment, cell proliferation, multipotency, and differentiation phenotypes of AMSCs upon osteogenic induction. High-resolution scanning electron microscopy and histology revealed that AMSCs adhere to the porous metallic surface. Compared to standard tissue culture plastic, AMSCs grown in the porous titanium microenvironment showed differences in temporal expression for genes involved in cell cycle progression (CCNB2, HIST2H4), extracellular matrix production (COL1A1, COL3A1), mesenchymal lineage identity (ACTA2, CD248, CD44), osteoblastic transcription factors (DLX3, DLX5, ID3), and epigenetic regulators (EZH1, EZH2). We conclude that metal orthopedic implants can be effectively seeded with clinical-grade stem/stromal cells to create a pre-conditioned implant. © 2016 Elsevier B.V.


PubMed | Stryker Orthopedics
Type: Journal Article | Journal: The journal of knee surgery | Year: 2011

The objective of this study was to develop a novel method to quantify rotational micromotion of modular tibial components that incorporates physiologic loading conditions, a physiologic test environment, and constraint characteristics of the articulating surface. The methodology is reviewed and data are presented on four total knee designs. Results showed the design with a rotational stabilizing island to demonstrate the most capability in resisting rotational micromotion for a given reacted torque, followed by a full peripheral capture device, then a partial peripheral capture device, and then a full peripheral capture device with a posterior lipped edge. Under walking and stair-climbing loads, the full peripheral capture device imparts more torque to the insert than the other designs due to the higher constraint of its articulating surface and thus experiences the most micromotion. The rotational stabilizing island device reveals the least amount of motion, due to a combination of its locking mechanism and a less constrained articular surface.

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