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Cape Town, South Africa

Dominique J.K.,Office of Global Research | Ortiz-Osorno A.A.,Clinical Research Implementation Subject Matter Expert | Ortiz-Osorno A.A.,National Institute of Allergy and Infectious Diseases | Fitzgibbon J.,National Institute of Allergy and Infectious Diseases | And 7 more authors.
Clinical Infectious Diseases | Year: 2015

Novel diagnostics have been widely applied across human immunodeficiency virus (HIV) and tuberculosis prevention and treatment programs. To achieve the greatest impact, HIV and tuberculosis diagnostic programs must carefully plan and implement within the context of a specific healthcare system and the laboratory capacity. Methods. A workshop was convened in Cape Town in September 2014. Participants included experts from laboratory and clinical practices, officials from ministries of health, and representatives from industry. Results. The article summarizes best practices, challenges, and lessons learned from implementation experiences across sub-Saharan Africa for (1) building laboratory programs within the context of a healthcare system; (2) utilizing experience of clinicians and healthcare partners in planning and implementing the right diagnostic; and(3) evaluating the effects of new diagnostics on the healthcare system and on patient health outcomes. Conclusions. The successful implementation of HIV and tuberculosis diagnostics in resource-limited settings relies on careful consideration of each specific context. Source


Myers J.,University of Cape Town | Young T.,Strategic Evaluation | Galloway M.,Strategic Evaluation | Manyike P.,Strategic Evaluation | And 2 more authors.
South African Medical Journal | Year: 2011

Projections show that the effects of climate change in Africa will not be uniform over the region. The region is extremely vulnerable to climate change because of poverty, a high pre-existing disease burden, fragmented health services and water and food insecurity. Despite the consensus that locally relevant information is necessary to inform policy and practice related to climate change, very few studies assessing the association between climate change and health in southern Africa have been conducted. More comprehensive information is therefore urgently needed for the southern African region to estimate the health risks from projected future changes in climate. Source


Myers J.,University of Cape Town | Young T.,Strategic Evaluation | Galloway M.,Strategic Evaluation | Manyike P.,Strategic Evaluation | And 2 more authors.
South African Medical Journal | Year: 2011

Anthropogenic climate change and anticipated adverse effects on human health as outlined by the Intergovernmental Panel on Climate Change (IPCC) are taken as givens. A conceptual model for thinking about the spectrum of climate-related health risks ranging from distal and infrastructural to proximal and behavioural and their relation to the burden of disease pattern typical of sub-Saharan Africa is provided. The model provides a tool for identifying modifiable risk factors with a view to future research, specifically into the performance of interventions to reduce the impact of climate change. Source

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