Tang Y.-Q.,Shanghai Institute of Applied Mathematics and Mechanics |
Tang Y.-Q.,Shanghai Institute of Technology |
Chen L.-Q.,Shanghai Institute of Applied Mathematics and Mechanics |
Chen L.-Q.,Shanghai University |
And 2 more authors.
Nonlinear Dynamics | Year: 2012
Nonlinear forced vibrations of in-plane translating viscoelastic plates subjected to plane stresses are analytically and numerically investigated on the steady-state responses in external and internal resonances. A nonlinear partial-differential equation with the associated boundary conditions governing the transverse motion is derived from the generalized Hamilton principle and the Kelvin relation. The method of multiple scales is directly applied to establish the solvability conditions in the primary resonance and the 3:1 internal resonance. The steady-state responses are predicted in two patterns: single-mode and two-mode solutions. The Routh-Hurvitz criterion is used to determine the stabilities of the steady-state responses. The effects of the in-plane translating speed, the viscosity coefficient, and the excitation amplitude on the steady-state responses are examined. The differential quadrature scheme is developed to solve the nonlinear governing equations numerically. The numerical calculations confirm the approximate analytical results regarding the single-mode solutions of the steady-state responses. © 2011 Springer Science+Business Media B.V.
Mo J.-Q.,Anhui Normal University |
Mo J.-Q.,stitutes of Shanghai Universities
Communications in Theoretical Physics | Year: 2010
The corresponding solution for a class of disturbed KdV equation is considered using the analytic method. From the generalized variational iteration theory, the problem of solving soliton for the corresponding equation translates into the problem of variational iteration. And then the approximate solution of the soliton for the equation is obtained. © 2010 Chinese Physical Society and IOP Publishing Ltd.
Zhou T.,Shanghai JiaoTong University |
Wang L.,Shanghai JiaoTong University |
Zhu K.-Y.,Shanghai JiaoTong University |
Dong M.,Shanghai JiaoTong University |
And 7 more authors.
Blood | Year: 2011
The primitive hematopoietic stem/progenitor cells (HSPCs) during embryonic hematopoiesis are thought to be short-lived (SL) with limited self-renewal potential. The fate and consequence of these short-lived HSPCs, once reprogrammed into "long-lived" in a living animal body, remain unknown. Here we show that targeted expression of a dominant-negative C/ebpα (C/ebpαDN) in the primitive SL-HSPCs during zebrafish embryogenesis extends their life span, allowing them to survive to later developmental stage to colonize the definitive hematopoietic sites, where they undergo a proliferative expansion followed by erythropoietic dysplasia and embryonic lethality because of circulation congestion. Mechanistically, C/ebpαDN binds to a conserved C/EBP-binding motif in the promoter region of bmi1 gene, associated with a specific induction of bmi1 transcription in the transgenic embryos expressing C/ebpαDN. Targeted expression of Bmi1 in the SL-HSPCs recapitulates nearly all aberrant phenotypes induced by C/ebpαDN, whereas knockdown of bmi1 largely rescues these abnormalities. The results indicate that Bmi1 acts immediately downstream of C/ebpαDN to regulate the survival and self-renewal of HSPCs and contribute to the erythropoietic dysplasia. © 2011 by The American Society of Hematology.
Chen L.-Q.,Shanghai University |
Chen L.-Q.,stitutes of Shanghai Universities |
Tang Y.-Q.,Shanghai University |
Tang Y.-Q.,Shanghai Institute of Technology
Journal of Sound and Vibration | Year: 2011
Nonlinear parametric vibration is investigated for axially accelerating viscoelastic beams subject to parametric excitations resulting from longitudinally varying tensions and axial speed fluctuations. The effects of the longitudinally varying tension due to the axial acceleration are highlighted, while the tension was assumed to be longitudinally uniform in previous studies. The dependence of the tension on the finite axial support rigidity is also modeled. The governing equations of coupled planar vibration and the associated boundary conditions are derived from the generalized Hamilton principle and the viscoelastic constitutive relation. The equation is simplified into a governing equation of transverse nonlinear vibration in small but finite stretching problems. The governing equation of transverse vibration is a nonlinear integro-partial-differential equation with time-dependent and space-dependent coefficients. The method of multiple scales is employed to analyze the combination and the principal parametric resonances with the focus on steady-state responses. In the difference resonance, there is only trivial zero response which is always stable. In the summation and the principal resonances, the trivial responses may become unstable and bifurcate into nontrivial responses for certain excitation frequencies. Some numerical examples indicate that the longitudinal tension variation makes the instability frequency intervals of trivial responses small and the nontrivial response amplitudes large (small) in the summation (principal) resonance. It is also found that the nontrivial responses are not sensitive to the axial support rigidity. Numerical solutions are calculated via the differential quadrature to support results via the method of multiple scales. © 2011 Elsevier Ltd. All rights reserved.
Chen L.-W.,Anhui University of Science and Technology |
Wang G.-L.,Anhui University of Science and Technology |
Lu X.-Y.,Anhui University of Science and Technology |
Lu X.-Y.,stitutes of Shanghai Universities
Journal of Fluid Mechanics | Year: 2011
Numerical investigation of a sonic jet from a blunt body opposing a supersonic flow with a free stream Mach number M∞ = 2. 5 was carried out using large-eddy simulation for two total pressure ratios of the jet to the free stream, i.e. P = 0. 816 and 1.633. Results have been validated carefully against experimental data. Various fundamental mechanisms dictating the flow phenomena, including shock/jet interaction, shock/shear-layer interaction, turbulent shear-layer evolution and coherent structures, have been studied systematically. Based on the analysis of the flow structures and features, two typical flow states, i.e. unstable and stable states corresponding to the two values of P, are identified and the behaviours relevant to the flow states are discussed. Small-scale vortical structures mainly occur in the jet column, and large-scale vortices develop gradually in a recirculation region when the jet terminates through a Mach disk and reverses its orientation as a conical free shear layer. The turbulent fluctuations are enhanced by the rapid deviation of the shear layer and the interaction with shock waves. Moreover, the coherent structures of the flow motion are analysed using the proper orthogonal decomposition technique. It is found that the dominant mode in the cross-section plane exhibits an antisymmetric character for the unstable state and an axisymmetric one for the stable state, while statistical analysis of unsteady loads indicates that the side loads can be seen as a rotating vector uniformly distributed in the azimuthal direction. Further, we clarify a feedback mechanism whereby the unsteady motion is sustained by the upstream-propagating disturbance to the Mach disk through the recirculation subsonic region and downstream propagation in the conical shear layer. Feedback models are then proposed which can reasonably well predict the dominant frequencies of the two flow states. The results obtained in this study provide physical insight into the understanding of the mechanisms relevant to the opposing jet/supersonic flow interaction. © 2011 Cambridge University Press.