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Columbia, MO, United States

Stephens College is a women's college located in Columbia, Missouri. It is the second oldest female educational establishment that is still a women's college in the United States. It was founded on August 24, 1833, as the Columbia Female Academy. In 1856, David H. Hickman helped secure the college's charter under the name The Columbia Female Baptist Academy. In the late 19th century it was renamed Stephens Female College after James L. Stephens endowed the college with $20,000. The campus includes a National Historic District: Stephens College South Campus Historic District. Wikipedia.

Ecotourism shows great potential for primate conservation, but further investigation through an ethnoprimatological lens is vital to understanding species-specific variation in human-nonhuman primate interactions at ecotourism sites. This study measured the rates and types of human-monkey interactions, the participants in these encounters, and the association between tourist numbers and interaction rates with white-faced capuchin monkeys (Cebus imitator) and mantled howlers (Alouatta palliata) at the Curú Wildlife Refuge in western Costa Rica. I collected data through 15-min all-occurrence samples for human-monkey interactions between January 2006 and December 2007. I recorded and analyzed a total of 1949 discrete interactions, representing one tourist group and one non-tourist group for each species. For both species, tourist groups showed more varied and more intense-but not more frequent-human-monkey interactions than the non-tourist groups. White-faced capuchins differed from mantled howlers in their greater frequency and more variable forms of human-monkey interactions. White-faced capuchins also showed a more gregarious pattern of interactions than mantled howlers, with most capuchin interactions being initiated by the monkeys and involving multiple actors. Although mantled howler human interaction rates correlated positively with levels of human traffic, white-faced capuchins did not show this relationship. These findings demonstrate that the differences in human-monkey interactions across species are an important consideration for the management of primate tourism sites. This study suggests that species-specific guidelines for ecotourism would reduce visitor impact on nonhuman primates. © 2014 Springer Science+Business Media New York. Source

Roy L.,Indian Association for The Cultivation of Science | Mittal S.,Stephens College | Paul A.,Indian Association for The Cultivation of Science
Angewandte Chemie - International Edition | Year: 2012

Chemical hydrogen storage: Theoretical investigations showed that the dehydrogenation of chemisorbed hydrogen atoms on boron nitride nanotubes (BNNT) could be triggered by appropriate reagents through simultaneous proton and hydride transfer (see picture). The computed free-energy of the activation barrier for the reduction of formaldehyde to methanol by chemisorbed hydrogen atoms on a zigzag BNNT was predicted to be 12.7kcal mol -1 in THF. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source

Kinahan C.E.,Stephens College | Mazloom S.,Cleveland Clinic | Fernandez A.P.,Cleveland Clinic
British Journal of Dermatology | Year: 2015

Background Smoking is a well-established risk factor for developing psoriasis and is associated with development of more severe disease. Smoking cessation does not appear to result in clinical improvement of psoriasis. Whether smoking in patients with psoriasis impacts response to systemic therapy is unknown. Objectives To determine whether smokers with psoriasis with or without psoriatic arthritis respond to systemic agents as well as nonsmokers do. Methods We performed a retrospective review of patients with moderate-to-severe psoriasis with or without psoriatic arthritis seen at our institution, who were either active smokers or nonsmokers, and calculated changes in Physician's Global Assessment (PGA) scores after 3-16 months of systemic treatment. We also calculated the average number of systemic treatments tried per patient. Results Sixty-six patients (46 nonsmokers, 20 smokers) met our inclusion criteria. Changes in PGA scores between baseline and 3-16 months after initiation of systemic treatment did not significantly differ between smokers and nonsmokers, nor did the average number of systemic treatments tried per patient. We detected a borderline significant trend in the percentage of patients who had significant outcomes after treatment, with a higher percentage of patients smoking < 10 cigarettes daily achieving target PGA scores compared with those smoking > 10 cigarettes daily. Limitations of our study include its retrospective nature and the relatively small number of patients meeting our inclusion criteria. Conclusions In our retrospectively studied cohort, smoking did not affect response to systemic treatment in patients with psoriasis. A prospective study examining the complex relationship between smoking, psoriasis and response to systemic therapy is warranted to explore this association better. © 2014 British Association of Dermatologists. Source

Sridharan R.,Stephens College | Karp J.M.,Harvard University | Zhao W.,University of California at Irvine
Biochemical Society Transactions | Year: 2014

For the last decade, stem cell therapies have demonstrated enormous potential for solving some of the most tragic illnesses, diseases and tissue defects worldwide. Currently, more than 1300 clinical trials use stem cell therapy to solve a spectrum of cardiovascular, neurodegenerative and autoimmune diseases (http://www.clinicaltrials.gov, Jan 2014, search term: stem cell therapy; only currently recruiting and completed studies are included in the search). However, the efficacy of stem cell transplantation in patients has not been well established, and recent clinical trials have produced mixed results. We attribute this lack of efficacy in part to an incomplete understanding of the fate of stem cells following transplantation and the lack of control over cell fate, especially cell-homing and therapeutic functions. In the present review, we present two of our recently developed technologies that aim to address the above-mentioned bottlenecks in stem cell therapy specifically in the areas of MSCs (mesenchymal stem cells): (i) aptamer-based cell-surface sensors to study cellular microenvironments, and (ii) mRNA engineering technology to enhance the homing and immunomodulatory efficacy of transplanted stem cells. The first engineering strategy aims to elucidate the basic cellular signalling that occurs in the microenvironment of transplanted stem cells in real time. The second technique involves a simple mRNA transfection that improves the homing and anti-inflammatory capability of MSCs. Although we have specifically applied these engineering techniques to MSCs, these strategies can be incorporated for almost any cell type to determine and control the fate of transplanted stem cells. © 2014 Biochemical Society. Source

Ge Y.,Stephens College | O'Shea D.F.,Stephens College
Chemical Society Reviews | Year: 2016

Azadipyrromethenes were first described over 70 years ago as blue pigments, but now are rapidly emerging as a compound class with highly desirable near infrared photophysical properties. Since the turn of the century several routes to azadipyrromethenes have been developed and numerous post-synthesis derivatizations have allowed for their exploitation in both biological and material sciences. The relative ease of access to specifically designed derivatives is now allowing their use in multiple technological formats from real-time fluorescence imaging, to solar energy materials, to optoelectronic devices and many more. In this review we have highlighted the synthetic component of this story as it is the ability to generate the designer azadipyrromethene that opens the door to exciting applications. © 2016The Royal Society of Chemistry. Source

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