Stephen F. Austin State University is a public university located in Nacogdoches, Texas, United States. Founded as a teachers' college in 1923, the university was named after one of Texas' founding fathers, Stephen F. Austin. Its campus resides on part of the homestead of another Texas founding father, Thomas Jefferson Rusk. Stephen F. Austin is one of four independent public universities in Texas . Stephen F. Austin State University is accredited by the Southern Association of Colleges and Schools to award bachelor's, master's, and doctoral degrees. Wikipedia.
Pollock W.,Stephen F. Austin State University
Crime and Delinquency | Year: 2014
From demographics, to technology, to attitudes, the U.S. population has changes since the 1970s. Over the past 40 years, policing has also changed to include more individuals who are female and non-White. Despite all of the changes, no study has yet been conducted to determine whether predictors of police contact, including factors such as race and gender, are consistent over time. The current study used multilevel Bernoulli models and logistic regression to examine two generations of respondents from the National Youth Survey Family Study. Results indicate some consistency in predictors of police contact between the two generations, with two notable exceptions: gender and socioeconomic status. Implications for police policy and practice are discussed. © 2012 SAGE Publications.
Fritzler J.M.,Stephen F. Austin State University |
Zhu G.,Texas A&M University
Journal of Antimicrobial Chemotherapy | Year: 2012
Background: Cryptosporidium parvum causes an opportunistic infection in AIDS patients, and no effective treatments are yet available. This parasite possesses a single fatty acyl-CoA binding protein (CpACBP1) that is localized to the unique parasitophorous vacuole membrane (PVM). The major goal of this study was to identify inhibitors from known drugs against CpACBP1 as potential new anti-Cryptosporidium agents. Methods: A fluorescence assay was developed to detect CpACBP1 activity and to identify inhibitors by screening known drugs. Efficacies of top CpACBP1 inhibitors against Cryptosporidium growth in vitro were evaluated using a quantitative RT-PCR assay. Results: Nitrobenzoxadiazole-labelled palmitoyl-CoA significantly increased the fluorescent emission upon binding to CpACBP1 (excitation/emission 460/538 nm), which was quantified to determine the CpACBP1 activity and binding kinetics. The fluorescence assay was used to screen a collection of 1040 compounds containing mostly known drugs, and identified the 28 most active compounds that could inhibit CpACBP1 activity with sub-micromolar IC 50 values. Among them, four compounds displayed efficacies against parasite growth in vitro with low micromolar IC 50 values. The effective compounds were broxyquinoline (IC 50 64.9 μM), cloxyquin (IC 50 25.1 μM), cloxacillin sodium (IC 50 36.2 μM) and sodium dehydrocholate (IC 50 53.2 μM). Conclusions: The fluorescence ACBP assay can be effectively used to screen known drugs or other compound libraries. Novel anti-Cryptosporidium activity was observed in four top CpACBP1 inhibitors, which may be further investigated for their potential to be repurposed to treat cryptosporidiosis and to serve as leads for drug development. © The Author 2011. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved.
Mcdonald S.M.,Stephen F. Austin State University
International Journal of Nursing Knowledge | Year: 2012
PURPOSE: Concept analysis methodology by Walker and Avant (2005) was used to define, describe, and delimit the concept of perception. DATA SOURCE: Nursing literature in the Medline database was searched for definitions of "perception." DATA SYNTHESIS: Definitions, uses, and defining attributes of perception were identified; model and contrary cases were developed; and antecedents, consequences, and empirical referents were determined. CONCLUSIONS: An operational definition for the concept was developed. IMPLICATIONS FOR NURSING PRACTICE: Nurses need to be cognizant of how perceptual differences impact the delivery of nursing care. In research, a mixed methodology approach may yield a richer description of the phenomenon and provide useful information for clinical practice. © 2011, The Author International Journal of Nursing Knowledge © 2011, NANDA International.
Stephen F. Austin State University | Date: 2014-02-17
In some embodiments, the compositions and methods relate to compounds isolated from plants in the Salviniaceae family, pharmaceutical compositions comprising the same, and methods of using the same.
Agency: NSF | Branch: Standard Grant | Program: | Phase: S-STEM:SCHLR SCI TECH ENG&MATH | Award Amount: 623.76K | Year: 2015
This NSF Scholarships in Science, Technology, Engineering, and Mathematics (S-STEM) project at Stephen F. Austin State University (SFASU) will provide academic, social, career preparation, and scholarship support to approximately twenty (20) financially deserving mathematics and biology majors with high academic potential. The goals of the Science and Mathematics Attraction, Retention, and Training for Texas (SMART Texas) program are to: (1) increase the number of students entering and completing a mathematics or biology major; (2) prepare mathematics and biology majors for the workforce or graduate study; and (3) investigate and identify key elements of a replicable model for STEM student success with a special focus on first generation low-income and other underrepresented groups of undergraduate students.
This SMART Texas project will incorporate a combination of innovative and established best practice strategies to increase recruitment and retention, as well as improve student success and graduation rates. The scholarship students will engage in a STEM living learning community where they will be involved with STEM peers and STEM faculty in both academic and non-academic settings. S-STEM students will have access to cohort mentoring, dedicated academic mentoring by faculty in their discipline, internships and undergraduate research opportunities (including laboratory research), and a variety of networking opportunities including support to attend and participate in discipline conferences. The planned combination of strategies will be implemented and investigated to determine obstacles students face and best practices to help overcome these obstacles to increase participation, retention, graduation, and overall student success, especially for underrepresented groups. A paired longitudinal study will be conducted to examine the effects of these interventions over time when compared to nonparticipating STEM majors. Results will be disseminated throughout the STEM community.