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Real E.M.,State University of Mato Grosso do Sul
Proceedings - 2016 5th Brazilian Conference on Intelligent Systems, BRACIS 2016 | Year: 2016

The main goal of clustering algorithms is to organize a given set of data patterns into groups (clusters) and their main strategy is to group patterns based on their similarity. However, some clustering algorithms also require as an input parameter, the number of clusters the induced clustering should have, or then, a threshold value used for limiting for the number of induced clusters. Both, the number of cluster as well a threshold value are often unknown, however it is well-known that results of clustering tasks can be very sensitive to them. This work presents a method for empirically estimating both values. The method is based on multiple runs of sequential clustering algorithms, by using increasing threshold values. Results from experiments conducted using several data domains from two repositories, the UCI and the Keel, as well as a few artificially created data, are presented and a comparative analysis is carried out, as evidence of the good estimates on both values given by the method. © 2016 IEEE.

Villar L.,Industrial University of Santander | Dayan G.H.,Sanofi S.A. | Arredondo-Garcia J.L.,Instituto Nacional Of Pediatria | Rivera D.M.,Organizacion Para El Desarrollo y la Investigacion Salud en Honduras ODISH | And 16 more authors.
New England Journal of Medicine | Year: 2015

immunogenicity subgroup of 1944 children had seropositive status for one or more dengue serotypes. In the per-protocol population, there were 176 VCD cases (with 11,793 person-years at risk) in the vaccine group and 221 VCD cases (with 5809 person-years at risk) in the control group, for a vaccine efficacy of 60.8% (95% confidence interval [CI], 52.0 to 68.0). In the intention-to-treat population (those who received at least one injection), vaccine efficacy was 64.7% (95% CI, 58.7 to 69.8). Serotype-specific vaccine efficacy was 50.3% for serotype 1, 42.3% for serotype 2, 74.0% for serotype 3, and 77.7% for serotype 4. Among the severe VCD cases, 1 of 12 was in the vaccine group, for an intention-to-treat vaccine efficacy of 95.5%. Vaccine efficacy against hospitalization for dengue was 80.3%. The safety profile for the CYD-TDV vaccine was similar to that for placebo, with no marked difference in rates of adverse events. Conclusions The CYD-TDV dengue vaccine was efficacious against VCD and severe VCD and led to fewer hospitalizations for VCD in five Latin American countries where dengue is endemic. (Funded by Sanofi Pasteur; ClinicalTrials.gov number, NCT01374516.) Copyright © 2015 Massachusetts Medical Society. All rights reserved.

Anger K.,Alfred Wegener Institute for Polar and Marine Research | Hayd L.,State University of Mato Grosso do Sul
Aquatic Biology | Year: 2010

The palaemonid shrimp Macrobrachium amazonicum (Heller 1862) lives in coastal rivers and estuaries along the northern coasts of South America as well as in inland waters of the Amazon, Orinoco, and upper La Plata (Paraguay-Paraná) River systems. In an experimental investigation on a little known, hydrologically isolated population from the Pantanal (upper Paraguay basin), we studied ontogenetic changes in early larval feeding and growth. Similar to a previously studied population from the Amazon estuary, the first zoeal stage (Z I) hatched with conspicuous fat reserves remaining from the egg yolk. While Z I is a non-feeding stage, Z II is facultatively lecithotrophic, and Z III is planktotrophic, requiring food for further development. Compared to estuarine larvae, those from the Pantanal hatched with lesser amounts of lipid droplets, and they survived for significantly shorter periods in the absence of food (maximally 8-9 d versus 14-15 d, at 29°C). Both populations moulted in short intervals (ca. 2 d) through larval stages Z I to VI. Biomass increased exponentially, with a higher growth rate observed in the Pantanal larvae. These develop in lentic inland waters, where high productivity allows for fast growth of planktonic predators. By contrast, the early larval stages of the Amazon population show a higher endotrophic potential and are thus better adapted to conditions of food limitation occurring during riverine downstream transport through lotic waters, towards coastal marine habitats. Initial larval independence from food in the Pantanal clade is interpreted as a plesiomorphic trait persisting from coastal marine ancestors. © Inter-Research 2010.

Ferreira A.C.,State University of Mato Grosso do Sul
Genetics and molecular research : GMR | Year: 2012

Insects use pheromones as a means of chemical communication. Pheromones act on individual receptors and produce specific behavioral or physiological responses that are fundamental to intra- and interspecific recognition. The objective of this study was to evaluate the interspecific differences among the linear hydrocarbon profiles of the cuticles of 3 wasp species of the genus Mischocyttarus. The chemical strategy that permits an interaction among 2 of these species was also examined about their hydrocarbon profiles. The cuticular hydrocarbons present on the abdomen of each individual were extracted with hexane in an ultrasonic bath and analyzed using gas chromatography with a flame ionization detector. The results suggested that the wasp species have distinct chemical signatures as the linear hydrocarbons of their cuticles. However, these signatures are more alike in those with similar morphological and behavioral aspects. These similarities facilitate an interaction of facultative parasitism observed among these species, in which the invaders acquire parts of the chemical signature of the host colony, possibly as a chemical strategy to increase the likelihood that an invader will be accepted by the females of a host colony. Both invader and host have their own chemical signature changed by the first contact between the species.

The objective of this study was to evaluate the effect of different concentrations (0; 50; 100 and 150 mg L-1) of paclobutrazol (PBZ) on growth, side shoot emission and yield of two tomato hybrids (Jennifer and AF 7631), cultivated in open field and in protected environment. The work was conducted from April to October of 2007, at UNESP - Campus of Ilha Solteira, State of São Paulo. The PBZ was applied to seedlings 15 days after sowing, and its effects were evaluated, considering the tested concentrations, for tomato plants after the transplant. A randomized blocks design was used, in a factorial scheme, with analysis for series of experiments, in a fixed model, consisting of 4 replicates for environment and 9 plants per plot. As results, the hybrid Jennifer showed higher rates of absolute growth, resulting in higher plants than AF 7631, on the 60th day after the transplantation, but, with no differences between them regarding side shooting and crop yield. In the greenhouse, higher plants were obtained, with higher side shooting and higher yield than that observed in the open field. The use of increasing concentrations of paclobutrazol reduced the height of plants and their growth rate, decreased side shooting, and reduced the crop yield.

Narciso V.,State University of Mato Grosso do Sul
Mathematical Methods in the Applied Sciences | Year: 2015

This paper is concerned with the existence of a global attractor for the nonlinear viscoelastic beam equation with past history memory utt + kΔ2u - ∫-∞ tμ(t - τ)Δ2u(τ) dτ + f(u) + g(ut) = h, where g(ut) is a damping like |ut|rut and f(u) is a source term like |u|αu - |u|βu, by considering 0 ≤ β < α and r > 0. Copyright © 2014 John Wiley & Sons, Ltd.

Guterres Z.R.,State University of Mato Grosso do Sul
Mutation research | Year: 2013

The somatic mutation and recombination test (SMART) in wing cells of Drosophila melanogaster was used to test the mutagenic and recombinogenic activities of five aporphinoid alkaloids isolated from Ocotea acutifolia: thalicminine (1), (+)-dicentrine (2), (+)-ocoteine (3), (+)-6S-ocoteine N-oxide (4), and (+)-leucoxine (5). Third-stage larvae derived from the standard cross with wing cell markers mwh and/or flr(3) were treated chronically. The frequencies of mutant spots observed in marked heterozygous descendants revealed significant dose-dependent genotoxicity for alkaloids 1-4; compounds 1 and 2 were the most active. Alkaloids 1-4 also induced mitotic recombination. The presence of a methoxyl group at C-3 (as in compound 3) lowers its genotoxic effect relative to that of unsubstituted analogue 2, and the introduction of an N-oxide functionality (3 vs. 4) further reduces genotoxicity. The very planar conformation of oxo-aporphine alkaloid 1 may account for its higher genotoxicity vs. its less-planar analogues 3 and 4. As previously reported for (+)-dicentrine (2), alkaloids 1, 3, and 4 may also be DNA intercalating agents, interfering with the catalytic activity of topoisomerases. Copyright © 2013 Elsevier B.V. All rights reserved.

Ferreira S.M.B.,University of Cuiabá | Ignotti E.,State University of Mato Grosso do Sul | Gamba M.A.,Federal University of São Paulo
Revista de Saude Publica | Year: 2011

OBJECTIVE: To analyze factors associated with relapse of leprosy. METHODS: Retrospective case-control study including 159 patients older than 15 diagnosed with leprosy attending reference centers for leprosy in five municipalities in the state of Mato Grosso, central-western Brazil. Cases (n=53) were patients with relapsed leprosy diagnosed from 2005 to 2007 who were compared with controls (n=106) matching for gender and operational classification who were considered cured after treatment in 2005. Data was obtained from the local Notifiable Diseases Database, medical records and interviews. For the analyses conditional logistic regression and hierarchical approaches were used. RESULTS: After adjustment, the following factors were associated with relapse of leprosy: living in rental housing (OR = 4.1; 95%CI: 1.43; 12.04); living in houses constructed of wood and mud (OR = 3.2; 95%CI: 1.16;8.76); living with dwellings with more than five people (OR = 2.1; 95%CI: 1.03;4.36); alcohol use disorder (OR = 2.8; 95%CI: 1.17;6.79); irregular treatment (OR =3.8; 95%CI: 1.44; 10.02); lack of knowledge about the disease/treatment (OR = 2.6; 95%CI: 1.09;6.13); use of public transportation to get to the clinic (OR = 5.5; 95%CI: 2.36;12.63); clinical form of the disease (OR = 7.1; 95%CI:2.48;20.52), and treatment regimen (OR = 3.7; 95%CI: 1.49;9.11). CONCLUSIONS: The predictive factors of relapse are associated with housing conditions, living habits, organization of health services, clinical forms of leprosy and treatment regimen. Health services should educate patients on the disease as well as ensure consistent treatment.

Vilpoux O.F.,State University of Mato Grosso do Sul
Land Use Policy | Year: 2014

Cooperation is an important factor in improving the efficiency of agrarian reform, but hardly occurs, which is a serious problem in Brazil. This research tries to explain why cooperation is so difficult in Brazilian settlements. It focuses on the Midwest of Brazil, a region with a high concentration of land, located in the main region for production of commodities. Research combines a New Institutional approach with aspects from the economic sociology. The model developed in the paper is original and highlights factors responsible for cooperation. Research differentiates institutional arrangements according to asset specificity and sunk costs. Beside associations for representation with public authorities, where cooperation is easier, cooperative arrangements need specific investments from the settlers, who require warranties before participating. Institutions serve as warranties for adopted governances. In the case of cooperation in Brazilian settlements, these warranties should come from informal institutions, which can be a problem in some communities. Leadership of a producer can also have an important role in hierarchical networks. © 2014 Elsevier Ltd.

Da Graca C.P.M.,State University of Mato Grosso do Sul | Antonialli Jr. W.F.,State University of Mato Grosso do Sul
Sociobiology | Year: 2011

Inventories of species contribute valuable information on the ecological characteristics of a region and increase knowledge of its natural resources. Few inventories of social wasps have been made in Mato Grosso do Sul, and none on polistines. The aim of this work was carry out an inventory of social wasps in nine fragments of riparian forest of the municipality of Bataypora, Mato Grosso do Sul state Brazil, to clarify the abundance, diversity, and richness of the group and evaluate the efficiencies of different sampling methodologies. The study was performed between November 2008 and March 2009. We used both active searching and attractive traps, in which 512 individuals of 18 species of six genera were captured. Genera Polybia and Polistes comprised 78% of the species collected. The diversity index was H' = 0.7259 and richness was S' = 18 species. Regarding the efficiency of the methodologies, the active search was more efficient, capturing 83% of total number of species present in this work, the honey-baited traps 50%, and the sardine-baited traps 28%. Agelaiapallipes comprised 67% of the total individuals collected by the attractive trap, and Polybia paulista comprised 28% of the total individuals captured by active searching. Comparing the results from active searching and attractive traps illustrated the importance of the use of more than one method, in order to record the largest possible number of species.

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