State Demonstration and Training Center

Āgra, India

State Demonstration and Training Center

Āgra, India

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PubMed | World Health Organization, Employees State Insurance Corporation Medical College and Post Graduate Institute of Medical science & Research, Post Graduate Institute of Medical Education and Research, WHO Country Office for India and 3 more.
Type: Journal Article | Journal: Public health action | Year: 2015

All multidrug-resistant tuberculosis (MDR-TB) patients who had completed 6 months of treatment under the Revised National Tuberculosis Control Programme (RNTCP) in Uttar Pradesh, the largest state in northern India.To determine the proportion of MDR-TB patients with regular follow-up examinations, and underlying provider and patient perspectives of follow-up services.A retrospective cohort study was undertaken involving record reviews of 64 eligible MDR-TB patients registered during April-June 2013 in 11 districts of the state. Patients and programme personnel from the selected districts were interviewed using a semi-structured questionnaire.A total of 34 (53.1%) patients underwent follow-up sputum culture at month 3, 43 (67.2%) at month 4, 36 (56.3%) at month 5 and 37 (57.8%) at month 6. Themes associated with irregular follow-up that emerged from the interviews were multiple visits, long travel distances, shortages of equipment at the facility and lack of knowledge among patients regarding the follow-up schedule.The majority of the MDR-TB patients had irregular follow-up visits. Provider-related factors outweigh patient-related factors on the poor follow-up examinations. The programme should focus on the decentralisation of follow-up services and ensure logistics and patient-centred counselling to improve the regularisation of follow up.


Singh V.,National JALMA Institute for Leprosy and Other Mycobacterial Diseases ICMR | Gaur R.,National JALMA Institute for Leprosy and Other Mycobacterial Diseases ICMR | Mittal M.,National JALMA Institute for Leprosy and Other Mycobacterial Diseases ICMR | Biswas S.K.,National JALMA Institute for Leprosy and Other Mycobacterial Diseases ICMR | And 6 more authors.
International Journal of Immunogenetics | Year: 2012

Crohn's disease-associated NOD 2 variants (Arg702Trp and 3020insC) were found to be monomorphic (wild), and 7 subjects were heterozygous for Gly908Arg SNP in 263 patients with tuberculosis, 260 patients with leprosy and 270 healthy controls residing in northern Indian states. This is the first report to suggest the minimal role of these variants in susceptibility/resistance to TB and leprosy in this population. © 2012 Blackwell Publishing Ltd.

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