Entity

Time filter

Source Type


Cai X.-H.,State Key Laboratory of Phytochemistry and Plant Resources | Cai X.-H.,CAS Kunming Institute of Botany | Shang J.-H.,Yunnan Institute of Medical Material | Feng T.,State Key Laboratory of Phytochemistry and Plant Resources | And 3 more authors.
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences | Year: 2010

The alkaloidal fraction of Alstonia scholaris leaves shows anti-inflammatory and analgesic bioactivity in vivo. A phytochemical study on this fraction led to the isolation of two novel alkaloids, scholarisine I and (±)-scholarisine II. Their structures were elucidated on the basis of spectroscopic methods, and a possible biogenesis is proposed. (±)-Scholarisine II selectively inhibited the inducible COX-2 rather than COX-1, and also markedly inhibited 5-LOX, comparable to positive controls. © 2010 Verlag der Zeitschrift für Naturforschung, Tübingen. Source


Zhang X.-Y.,State Key Laboratory of Phytochemistry and Plant Resources | Zhang X.-Y.,CAS Kunming Institute of Botany | Zhang X.-Y.,University of Chinese Academy of Sciences | Zhang R.-T.,State Key Laboratory of Phytochemistry and Plant Resources | And 9 more authors.
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences | Year: 2010

Two new compounds, ent-8(9)-pimarene-20-hydroxy-16-nor-15-oic acid (1) and 20S,24-epoxy-25,26,27-trisnor-24-oxo-3,4-seco-dammar-4(28), 22-dien-3-oic acid (2), along with four known compounds have been isolated from the bark of Dysoxylum hainanense. The new structures were elucidated by spectroscopic techniques (NMR, MS, UV, IR and optical rotation). The known compound, ent-8(9)-pimarene-15,16-diol (3), was reported from D. hainanense for the first time. © 2010 Verlag der Zeitschrift für Naturforschung, Tübingen. Source

Discover hidden collaborations